Results 71 to 80 of about 1,109,000 (367)

The Carcinoembryonic Antigen Gene Family [PDF]

, 1988
The molecular cloning of carcinoembryonic antigen (CEA) and several cross-reacting antigens reveals a basic domain structure for the whole family, which shows structural similarities to the immunoglobulin superfamily.
Thompson, John A., Zimmermann, Wolfgang
core  

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Reactive oxygen species modulator 1, a novel protein, combined with carcinoembryonic antigen in differentiating malignant from benign pleural effusion

Tumor Biology, 2017
The differential diagnosis of malignant pleural effusion and benign pleural effusion remains a clinical problem. Reactive oxygen species modulator 1 is a novel protein overexpressed in various human tumors. The objective of this study was to evaluate the
Xianmeng Chen, Na Zhang, Jiahui Dong, Gengyun Sun   +3 more
doaj   +1 more source

Cloning of the Complete Gene for Carcinoembryonic Antigen [PDF]

, 1990
Carcinoembryonic antigen (CEA) is a widely used tumor marker, especially in the surveillance of colonic cancer patients. Although CEA is also present in some normal tissues, it is apparently expressed at higher levels in tumorous tissues than in ...
Bona, Marion, Hassauer, Martin, Hefta, Laura J. F., Kleist, Sabine von, Maruya, Aiko, Schrewe, Heinrich, Shively, John E., Thompson, John A., Zimmermann, Wolfgang   +8 more
core  

Personalized Risk Assessment in Never, Light, and Heavy Smokers in a prospective cohort in Taiwan. [PDF]

, 2016
The objective of this study was to develop markedly improved risk prediction models for lung cancer using a prospective cohort of 395,875 participants in Taiwan.
Chow, Wong-Ho, Cunningham, Sonia, Gu, Jian, Huang, Maosheng, Huff, Chad, Lippman, Scott M, Pu, Xia, Roth, Jack A, Tsai, MinKwang, Tsao, Chwen Keng, Wen, Chi Pang, Wen, Christopher, Wu, Shuanbei, Wu, Xifeng, Ye, Yuanqing   +14 more
core   +1 more source

Deep Learning‐Powered Nanoplasmonic Biosensing Approach Enables Ultrasensitive Extracellular Vesicles Profiling for Cancer Screening

Advanced Science, EarlyView.
This study presents a Kolmogorov–Arnold network (KAN)‐powered nanoplasmonic biosensing platform for ultrasensitive detection of small extracellular vesicles in serum, enabling highly accurate pancreatic cancer screening. The method achieves an area under the curve (AUC) of 0.99 in a large clinical cohort, offering a robust and interpretable deep ...
Jiaheng Zhu, Yingqi Xiao, Xinyue Huang, Qiang Niu, Lihuang Zeng, Shaowei Lin, Mengqi Jiang, Tianhao Huang, Hanyang Chen, Yinong Xie, Yuan Gao, Wei Chen, Yiming Yan, Jiaqing Shen, Kaibin Chen, Yurong Dai, Zhipeng Zhang, Lijun Zeng, Yahong Chen, Boan Li, Jinfeng Zhu, Bo Li   +21 more
wiley   +1 more source

On-Site Detection of Carcinoembryonic Antigen in Human Serum

Biosensors, 2021
Real-time connectivity and employment of sustainable materials empowers point-of-care diagnostics with the capability to send clinically relevant data to health care providers even in low-resource settings. In this study, we developed an advantageous kit
Tohid Mahmoudi, Mohammad Pourhassan-Moghaddam, Behnaz Shirdel, Behzad Baradaran, Eden Morales-Narváez, Hamed Golmohammadi   +5 more
doaj   +1 more source

Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies

Advanced Science, EarlyView.
ARID1A, a SWI/SNF complex component, is frequently mutated in colorectal cancer (CRC). CRC with ARID1A/TP53 concurrent mutations shows marked sensitivity to WEE1 inhibition. ARID1A loss induces R‐loop‐mediated replication stress, impairs ATF3 transcription, and amplifies WEE1i‐induced DNA damage, suggesting a promising therapeutic vulnerability ...
Chi Zhang, Yanjing Zhu, Luoyan Ai, Jingyuan Wang, Shan Yu, Yichen Wang, Xiaojing Xu, Mengling Liu, Yiyi Yu, Mengxuan Zhu, Yutong Liu, Zhenghang Xu, Haojie Zhou, Huishan Li, Qihong Huang, Qing Liu, Ke Peng, Tianshu Liu   +17 more
wiley   +1 more source

Long-Range Chromosomal Mapping of the Carcinoembryonic Antigen (CEA) Gene Family Cluster [PDF]

, 1992
A long-range physical map of the carcinoembryonic antigen (CEA) gene family cluster, which is located on the long arm of chromosome 19, has been constructed.
Arakawa, Barnett, Barnett, Barnett, Benchimol, Berling, Bird, Bischoff-Delaloye, Bohn, Bordes, Brandriff, Branscomb, Brook, Brook, Brook, Carrano, Carrano, Chomczynski, Church, de Jong, Efstratiadis, Feinberg, Fritsch, Gold, Gold, Hinoda, Hinoda, Holland, Huang, Kamarck, Kodelja, Kuroki, Leusch, Lin, Mach, Maniatis, Nap, Niemann, Oikawa, Paxton, Pignatelli, Ropers, Sambrook, Sanger, Schonk, Schrewe, Schwartz, Sharkey, Shively, Slightom, Stallings, Steinmetz, Streydio, Svenberg, Tatarinov, Tatarinov, Thompson, Thompson, Thompson, Thompson, Thompson, Tonegawa, von Kleist, von Kleist, Willcocks, Willcocks, Willcocks, Zimmermann, Zimmermann, Zimmermann   +69 more
core   +1 more source

Non‐Destructively Quantifying the Whole‐Course Growth and Drug‐Response of PDOs by an Automatic Microfluidic System Utilizing Chemiluminescence Detection

Advanced Science, EarlyView.
The detection of secreted biomarkers enables molecular variations monitoring of organoid status. In this study, the non‐destructive quantification for the whole‐course growth and drug‐response of PDOs is first realized using a multifunctional microfluidic chip‐based system(ASMO) that integrates culturing, drug incubation, and biomarker detection ...
Yu Zhang, Daoyun Wang, Zhicheng Huang, Nan Zhang, Zhina Wang, Xin Wu, Anlan Zhang, Runzhi Yang, Tong Li, Zhibo Zheng, Yuxiao Lin, Naixin Liang, Zewen Wei   +12 more
wiley   +1 more source