Results 71 to 80 of about 1,065,405 (318)

A Wearable In‐Pad Diagnostic for the Detection of Disease Biomarkers in Menstruation Blood

Advanced Science, EarlyView.
MenstruAI integrates a paper‐based biosensor into sanitary pads to detect biomarkers in menstrual blood, enabling accessible, lab‐free diagnostics health. The platform supports early disease detection, especially in underserved communities, while challenging menstrual stigma and opening pathways for scalable, inclusive, and sustainable population ...
Lucas Dosnon, Thomas Rduch, Charlotte Meyer, Inge K. Herrmann   +3 more
wiley   +1 more source

Multiple myeloma presenting as CEA-producing rectal cancer

Rare Tumors, 2010
We report the case of a 57-year old patient with multiple myeloma, characterized by extramedullary involvement of the rectum at presentation. Malignant plasma cells were found to produce carcinoembryonic antigen (CEA), a tumor antigen more commonly ...
Giampaolo Talamo
doaj   +1 more source

Developing Biomaterial‐Based mRNA Delivery System for Lung Disease Treatment

Advanced Science, EarlyView.
Schematic illustration of biomaterial delivery mRNA for the treatment of lung diseases. Abstract Lung disease remains a persistent global health challenge. Advances in medical research have led to innovative strategies to combat these conditions, with biomaterials emerging as a promising platform for targeted drug delivery.
Qiancheng Gu, Huaqian Xue, Zhiyun Liu, Jiameng Rao, Lingyao Zeng, Chen Zhang, Lanjie Lei, Liyun Shi   +7 more
wiley   +1 more source

Single‐Droplet Dual‐Target Quantification of circRNA Biomarkers for Colorectal Cancer Screening

Advanced Science, EarlyView.
Circular RNAs are crucial in tumorigenesis. This study identifies circCK1γ3 and circWDR37 as dual plasma biomarkers for colorectal cancer (CRC) screening. It is developed Casµchip, a droplet microfluidic chip using Cas13a/b technology to quantify these biomarkers.
Jingsong Xu, Yu Liu, Junheng Zhang, Shuang Yang, Tianming Li, Haiqian Huang, Qian Liu, Hengliang Wang, Li Cao, Zhenghua An, Min Li, Hua Wang   +11 more
wiley   +1 more source

Does surgical intervention contribute to survival for patients with para‐aortic lymph node metastasis from colorectal cancer?

Annals of Gastroenterological Surgery, EarlyView.
Overall survival of patients who underwent surgical resection was significantly better compared to that of patients who underwent chemotherapy without surgical resection. These results highlight the benefit of surgical intervention to survival for patients with isolated para‐aortic lymph node metastasis or with resectable liver metastasis.
Akira Ouchi, Koji Komori, Sono Ito, Yusuke Kinugasa, Soichiro Ishihara, Akio Shiomi, Yukihide Kanemitsu, Takeshi Suto, Hiroki Takahashi, Yoichi Ajioka, on behalf of the study group for PALNM projected by JSCCR, Akinobu Furutani, Akira Hirata, Atsushi Ishibe, Eiji Sunami, Heita Ozawa, Hideki Ueno, Hideyuki Ishida, Hiroyuki Egi, Ichiro Takemasa, Jun Watanabe, Junichiro Hiro, Kay Uehara, Kazushige Kawai, Koya Hida, Manabu Shiozawa, Masaaki Ito, Masakatsu Numata, Masanori Hotchi, Masaya Hiyoshi, Masayuki Ohue, Michio Itabashi, Ryo Inada, Shuntaro Nagai, Takaya Kobatake, Takeshi Kato, Tomohiro Yamaguchi, Yasumasa Takii, Yasumitsu Hirano, Yoshihiro Kakeji   +39 more
wiley   +1 more source

Significance of Intraoperative Lavage Cytology in Perihilar Cholangiocarcinoma

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Perihilar cholangiocarcinoma (PHC) has a poor prognosis, with frequent early metastatic recurrence after curative resection. Peritoneal metastasis (PM) is particularly difficult to diagnose and predict. While intraoperative lavage cytology (CY) is a standard method to detect PM, its utility remains unclear in PHC.
Kentaro Miyake, Ryusei Matsuyama, Yusuke Nakazaki, Kota Sahara, Tomoaki Takahashi, Yutaro Kikuchi, Yasuhiro Yabushita, Yu Sawada, Yuki Homma, Itaru Endo   +9 more
wiley   +1 more source

Prognostic Significance of GLIM‐Defined Malnutrition in Patients With Resectable Pancreatic Adenocarcinoma Following Upfront Surgery

Annals of Gastroenterological Surgery, EarlyView.
The GLIM criteria are effective prognostic predictors in patients with resectable PDAC undergoing upfront surgery. Preoperative nutritional assessment using these criteria may contribute to determining treatment plans for resectable PDAC. ABSTRACT Aim Regarding the resectability of pancreatic adenocarcinoma (PDAC), not only anatomical factors but also ...
Takuya Mizumoto, Yoshihide Nanno, Jun Ishida, Dongha Lee, Kenji Fukushima, Shohei Komatsu, Hiroaki Yanagimoto, Sadaki Asari, Masahiro Kido, Takumi Fukumoto   +9 more
wiley   +1 more source

A Novel Magnetoelastic Immunosensor for Ultrasensitively Detecting Carcinoembryonic Antigen

Nanoscale Research Letters, 2018
A novel wireless immunosensor is developed for the ultra-sensitive detection of carcinoembryonic antigen. The optimum dimension of the microchips, as magnetoelastic sensitive units, was evaluated by simulation and experiments.
Yixia Zhang, Xing Guo, Lu Fan, Qiang Zhang, Shengbo Sang   +4 more
doaj   +1 more source

Patient‐Reported Outcomes and Surgical Results of Hand‐Sewn Versus Stapled Anastomosis for Lower Rectal Cancer Located 4–5 cm From the Anal Verge: A Subanalysis of the Ultimate Study

Annals of Gastroenterological Surgery, EarlyView.
Preserving anorectal function while ensuring oncological success is critical in lower rectal cancer surgery. This multicenter prospective study compared hand‐sewn and stapled anastomosis in 135 patients with tumors 4–5 cm from the anal verge. Although post‐operative complications and oncological outcomes were similar, stapled anastomosis consistently ...
Masakatsu Numata, Jun Watanabe, Yuichiro Tsukada, Yusuke Suwa, Yosuke Fukunaga, Yasumitsu Hirano, Kazuhiro Sakamoto, Hiroki Hamamoto, Masanori Yoshimitsu, Hisanaga Horie, Nobuhisa Matsuhashi, Yoshiaki Kuriu, Shuntaro Nagai, Madoka Hamada, Shinichi Yoshioka, Shinobu Ohnuma, Tamuro Hayama, Koki Otsuka, Yusuke Inoue, Kazuki Ueda, Yuji Toiyama, Satoshi Maruyama, Shigeki Yamaguchi, Keitaro Tanaka, Takeshi Naitoh, Masahiko Watanabe, Motoko Suzuki, Toshihiro Misumi, Masaaki Ito, Ultimate Trial Group in Japan Society of Laparoscopic Colorectal Surgery   +29 more
wiley   +1 more source

Occult mucin-producing urothelial-type adenocarcinoma of the prostate with elevated serum levels of carcinoembryonic antigen and carbohydrate antigen 19-9: Report of an autopsy-proven case

Urology Case Reports, 2019
Mucin-producing urothelial-type adenocarcinoma of the prostate (MPUAP) is a rare, aggressive neoplasm thought to originate from the prostatic urethral urothelium.
Keisuke Nonaka, Yoko Matsuda, Mototsune Kakizaki, Shoichiro Takakuma, Tomoyasu Matsubara, Shigeo Murayama, Toshiyuki Ishiwata, Masashi Kameyama, Kazuto Ogura, Sumiko Kobayashi, Tomio Arai   +10 more
doaj