Results 91 to 100 of about 172,865 (359)

Cyclic Strain and Macrophage‐Mediated Transport Govern Micron‐Sized PM2.5 Translocation across the Air–Blood Barrier

open access: yesAdvanced Science, EarlyView.
Using a dynamic, tri‐culture air‐blood barrier model, this study reveals that macrophage‐mediated transport governs micron‐sized particle translocation under cyclic strain. The process is highly size‐dependent that 2 µm particles are transported by macrophages, 0.2 µm particles diffuse passively, and 5 µm particles are effectively blocked.
Yongjian Li   +3 more
wiley   +1 more source

Health Damage and Repair Mechanism Related to Formaldehyde Released from Wood-based Panels

open access: yesBioResources, 2023
Wood-based panels, which contain wood raw materials along with urea-formaldehyde (UF) or phenol-formaldehyde (PF) resins, can increase the indoor air concentration of formaldehyde. Formaldehyde can stimulate the upper respiratory mucosa and cross-linking
Fan Gao   +6 more
doaj   +2 more sources

Hygiene and legal aspects of occupational exposure assessment to cytostatics

open access: yesMedycyna Pracy, 2018
The employers responsibilities for the assessment of occupational exposure to cytostatics in the workplace were analyzed in the light of existing legal regulations.
Małgorzata Kupczewska-Dobecka   +3 more
doaj   +1 more source

Identification and characterization of dysregulated P-element induced wimpy testis-interacting RNAs in head and neck squamous cell carcinoma. [PDF]

open access: yes, 2019
It is clear that alcohol consumption is a major risk factor in the pathogenesis of head and neck squamous cell carcinoma (HNSCC); however, the molecular mechanism underlying the pathogenesis of alcohol-associated HNSCC remains poorly understood.
Ku, Jonjei   +7 more
core  

Folic Acid‐Modified Ginger‐Derived Exosome‐Like Nanoparticles Co‐Delivering Sunitinib Suppress Renal Cell Carcinoma via PI3K‐Akt Pathway Inhibition, P‐gp Downregulation, and Macrophage Reprogramming

open access: yesAdvanced Science, EarlyView.
FPD‐GELNs co‐deliver Su and bioactive components. This active‐passive dual‐targeting strategy suppresses the progression of RCC through the following mechanisms: 1) inhibition of the PI3K‐Akt signaling pathway; 2) downregulation of ABCB1/P‐gp to enhance the chemosensitivity of RCC to Su; and 3) reprogramming of macrophages toward M1 polarization and ...
Haoyu Xu   +8 more
wiley   +1 more source

Binding occupational exposure limits for carcinogens in the EU – necessary but not sufficient to reduce risk

open access: yesScandinavian Journal of Work, Environment & Health, 2019
Johanson & Tinnerberg (1) discuss the role of binding occupational exposure limit values (BOELV) in the European Union and whether these are “good” or “bad”.
John W Cherrie
doaj   +1 more source

Dietary acrylamide intake by potato crisps consumers: A case of Nairobi County

open access: yesOpen Agriculture, 2020
The levels of acrylamide intake because of potato crisps consumption remains unknown in Kenyan context. This study assessed the exposure to acrylamide because of consumption of potato crisps in Nairobi, Kenya.
Abong George Ooko   +6 more
doaj   +1 more source

Point: From animal models to prevention of colon cancer. Systematic review of chemoprevention in min mice and choice of the model system. [PDF]

open access: yes, 2003
The Apc(Min/+) mouse model and the azoxymethane (AOM) rat model are the main animal models used to study the effect of dietary agents on colorectal cancer. We reviewed recently the potency of chemopreventive agents in the AOM rat model (D. E.
Corpet, Denis E., Pierre, Fabrice
core   +2 more sources

Atrazine and cancer incidence among pesticide applicators in the agricultural health study (1994-2007). [PDF]

open access: yes, 2011
Atrazine is a triazine herbicide used widely in the United States. Although it is an animal carcinogen, the mechanism in rodents does not appear to operate in humans.
Aaron Blair   +23 more
core   +1 more source

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