Results 51 to 60 of about 238,323 (340)
Journal of Clinical Investigation, 2003 Tobacco-related diseases such as lung cancer cause over 4.2 million deaths annually, with approximately 400,000 deaths per year occurring in the US. Genotoxic effects of tobacco components have been described, but effects on signaling pathways in normal ...
K. West +8 more
semanticscholar +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo
Cells, 2019 In most cancers, cellular origin and the contribution of intrinsic and extrinsic factors toward transformation remain elusive. Cell specific carcinogenesis models are currently unavailable. To investigate cellular origin in carcinogenesis, we developed a
Yu-Ting Yen +6 more
doaj +1 more source
The Influence of Electromagnetic Field Pollution on Human Health: A Systematic Review
Siriraj Medical Journal, 2021 Objective: Recent technological advances have exponentially expanded globally; harbouring upon Electromagnetic fields (EMF). The utilization of Electromagnetic field has become universal from everyday usage of electronic appliances such as micro wave ...
Monalisha Sahu +2 more
doaj +1 more source
The Regulation of Trace Metal Elements in Cancer Ferroptosis
Advanced Biology, EarlyView.The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang +5 more
wiley +1 more source
Dietary acrylamide intake by potato crisps consumers: A case of Nairobi County
Open Agriculture, 2020 The levels of acrylamide intake because of potato crisps consumption remains unknown in Kenyan context. This study assessed the exposure to acrylamide because of consumption of potato crisps in Nairobi, Kenya.
Abong George Ooko +6 more
doaj +1 more source
Phytochemicals from cruciferous plants protect against cancer by modulating carcinogen metabolism.
Journal of NutriLife, 2001 Several epidemiologic studies suggest that consumption of cruciferous vegetables may be particularly effective (compared with total fruit and vegetable consumption) in reducing cancer risk at several organ sites.
P. Talalay, J. Fahey
semanticscholar +1 more source
Head and neck squamous cell carcinoma
Nature Reviews Disease Primers, 2020 Head and neck squamous cell carcinomas (HNSCCs) originate from the mucosal epithelium in the oral cavity, pharynx and larynx, and are caused by viral infection or carcinogen exposure.
semanticscholar +1 more source
Multi‐Scaled Cellulosic Nanonetworks from Tunicates
Advanced Functional Materials, EarlyView.Microbial and plant nanonetworks of cellulose have enabled a wide range of high‐performance yet sustainable materials. Herein, a third class of cellulosic nanonetworks is showcased by exploiting the only animal tissue‐producing cellulose nanofibers, i.e., ascidians. An ultrastructure including spherical cells and a microvasculature with diameters of 50–
Mano Govindharaj +10 more
wiley +1 more source
口腔疾病防治, 2020 Oral potentially malignant disorders (OPMDs) refer to all epithelial lesions and conditions with an increased risk for malignant transformation, including oral leukoplakia, oral submucous fibrosis, oral lichen planus, erythroplakia, etc.
TONG Ting, CHENG Lei, REN Biao
doaj +1 more source