Results 51 to 60 of about 172,865 (359)

Mouse Models for Application in Colorectal Cancer: Understanding the Pathogenesis and Relevance to the Human Condition

Biomedicines, 2022
Colorectal cancer (CRC) is a malignant disease that is the second most common cancer worldwide. CRC arises from the complex interactions among a variety of genetic and environmental factors. To understand the mechanism of colon tumorigenesis, preclinical
Chuangen Li, Harry Cheuk-Hay Lau, Xiang Zhang, Jun Yu   +3 more
doaj   +1 more source

Listing Occupational Carcinogens

Environmental Health Perspectives, 2004
The occupational environment has been a most fruitful one for investigating the etiology of human cancer. Many recognized human carcinogens are occupational carcinogens. There is a large volume of epidemiologic and experimental data concerning cancer risks in different work environments.
Siemiatycki, J., Richardson, L., Straif, K., Latreille, B., Lakhani, R., Campbell, S., Rousseau, M. -C., Boffetta, P.   +7 more
openaire   +3 more sources

Tailoring the Properties of Functional Materials With N‐Oxides

Advanced Functional Materials, EarlyView.
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich, Michelle Kobus, Shirin Mesgarha, Erica Moretto, Laurens Grosche, Wolfgang Maison   +5 more
wiley   +1 more source

A Framework for Assessing the Rationality of Judgments in Carcinogenicity Hazard Identification [PDF]

, 1997
Arguing that guidelines for identifying carcinogens now lack a philosophically rigorous framework, the authors present an alternative that draws clear attention to the process of reasoning towards judgments of ...
Brown, Kenneth G., Crawford-Brown, Douglas J.   +1 more
core   +2 more sources

Beef meat promotion of dimethylhydrazine-induced colorectal carcinogenesis biomarkers is suppressed by dietary calcium [PDF]

, 2007
Red meat consumption is associated with increased risk of colorectal cancer. We have previously shown that haemin, Hb and red meat promote carcinogen-induced preneoplastic lesions: aberrant crypt foci (ACF) and mucin-depleted foci (MDF) in rats.
Corpet, Denis E., Guéraud, Françoise, Pierre, Fabrice, Santarelli, Raphaëlle L., Taché, Sylviane   +4 more
core   +3 more sources

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

Advanced Healthcare Materials, EarlyView.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk, JoAnn C. L. Schuh, Brad Bolon, Valerie S. Thomas, Jeffrey I. Everitt, Abraham Nyska, Jaime Paulin   +6 more
wiley   +1 more source

Phytochemical Profiling and Cytotoxic Potential of Musa acuminata Stem Extracts against Transformed Dysplastic Oral Keratinocytes (T-DOK): An In vitro Chemoprevention Study

Journal of Indian Academy of Oral Medicine and Radiology
Background: Oral cancers are often preceded with precancers, which paves the way for chemoprevention. Musa acuminata rich in phytochemical bioactives can serve as novel preference. Objective: To analyze the phytochemical bioactives of Musa acuminata (red
E. Gracelin Ranjitha, N. Rakesh, Angeline Deepthi, Deepu George Mathew, J. Venkatesh, Kandasamy Murugan   +5 more
doaj   +1 more source

Isolation and Identification of Pyrene-degrading Bacteria from Soils around Landfills in Shiraz and Their Growth Kinetic Assay [PDF]

Journal of Advanced Biomedical Sciences, 2011
Background & Objectives: Pyrene is a kind of carcinogen hydrocarbon in environment and one of the top 129 pollutants as ranked by the U.S.Environmental Pretection Agency (USEPA). Today's commodious method that is considered by many researchers is the use
Farshid Kafilzadeh, Fatemeh Hoshyaripour, Razieh Afrough, Hoshanq Jamali, Ghader Allahverdi   +4 more
doaj  

Do topical repellents divert mosquitoes within a community? Health equity implications of topical repellents as a mosquito bite prevention tool. [PDF]

, 2013
OBJECTIVES: Repellents do not kill mosquitoes--they simply reduce human-vector contact. Thus it is possible that individuals who do not use repellents but dwell close to repellent users experience more bites than otherwise.
DC Chavasse, Elizabeth Louise Turner, Emmanuel Titus Simfukwe, GF Killeen, JA Scott, John Vontas, LW Cohnstaedt, M Ditzen, M Rowland, Marta Ferreira Maia, Max Thele, MF Maia, N Hill, RW Steketee, Sangoro Peter Onyango, Sarah Jane Moore, SE Clarke, SJ Moore, SJ Moore, SP Carroll, SW Lindsay, TW Scott, Y Geissbühler   +22 more
core   +3 more sources

Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk

Advanced Healthcare Materials, EarlyView.
Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor, Giuseppe Longobardi, Or Kandli, Anne Krinsky, Opal Avramoff, Anshika Katyal, Koren Salomon, Adan Miari, Dana Venkert, Tania T. Barnatan, América García Alvarado, Shahar Greenberg, Ronit Satchi‐Fainaro   +12 more
wiley   +1 more source