Results 61 to 70 of about 385,377 (294)

Extracellular gamma-synuclein promotes tumor cell motility by activating β1 integrin-focal adhesion kinase signaling pathway and increasing matrix metalloproteinase-24, -2 protein secretion

open access: yesJournal of Experimental & Clinical Cancer Research, 2018
Background Increasing evidence reveals a significant correlation between gamma-synuclein (SNCG) level and tumor invasion and metastasis in various human cancers. Our previous investigation showed that SNCG could secrete into extracellular environment and
Caiyun Liu   +3 more
doaj   +1 more source

Circulating trans fatty acids are associated with prostate cancer in Ghanaian and American men

open access: yesNature Communications, 2023
The association between fatty acids and prostate cancer remains poorly explored in African-descent populations. Here, we analyze 24 circulating fatty acids in 2934 men, including 1431 prostate cancer cases and 1503 population controls from Ghana and the ...
Tsion Zewdu Minas   +22 more
doaj   +1 more source

Molecular Carcinogenesis

open access: yesDefinitions, 2020
Postgraduate Program in Health Science, Federal University of Maranhão, São Luís, Maranhão, Brazil Laboratory of Genetics and Molecular Biology, Department of Biology, Federal University of Maranhão, São Luís, Maranhão, Brazil Aldenora Bello Cancer ...
Chung S. Yang   +5 more
semanticscholar   +1 more source

Endothelins and carcinogenesis

open access: yesPostępy Higieny i Medycyny Doświadczalnej, 2016
Endothelins are a family of four endogenous peptides (ET-1, ET-2, ET-3, ET-4) secreted primarily in an inactive form by the endothelium. They are activated with the participation of converting enzyme. Numerous studies have described their pleiotropic biological activity.
Jacek Olender   +3 more
openaire   +3 more sources

The tumor–microbe connection

open access: yesMolecular Oncology, EarlyView.
Tumor‐associated bacteria (TAB) dynamically influence cancer biology by modulating tumor progression, metastatic spread, and therapeutic efficacy. Their presence redefines the tumor microenvironment (TME) as a microbial–host interface, yet mechanistic insights remain limited. Understanding TAB colonization routes, functional impacts, and crosstalk with
Gerlanda Vella, Maria Rescigno
wiley   +1 more source

Ancient variants of the Epstein–Barr virus (Herpesviridae, Lymphocryptovirus, HHV-4): hypotheses and facts

open access: yesВопросы вирусологии, 2020
Introduction. Molecular studies have shown that viruses appeared in the early stages of the evolution of life. For millions of years, viruses have evolved by changing old and acquiring new sequences in their RNA or DNA.
Kseniya V. Smirnova   +4 more
doaj   +1 more source

Critical role of FOXO3a in carcinogenesis

open access: yesMolecular Cancer, 2018
FOXO3a is a member of the FOXO subfamily of forkhead transcription factors that mediate a variety of cellular processes including apoptosis, proliferation, cell cycle progression, DNA damage and tumorigenesis.
Y. Liu   +9 more
semanticscholar   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf   +10 more
wiley   +1 more source

Intestinal microbiota enhances pancreatic carcinogenesis in preclinical models

open access: yesCarcinogenesis, 2018
Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer death in the United States yet data are scant regarding host factors influencing pancreatic carcinogenesis.
Ryan M. Thomas   +16 more
semanticscholar   +1 more source

Research progress on the metabolic transformation of Shenling Baizhu San under the influence of the gut microbiota

open access: yesAdvanced Chinese Medicine, EarlyView.
Abstract The gut microbiota plays a pivotal role in maintaining host metabolic homeostasis and overall physiological functions. Shenling Baizhu San (SLBZS), a time‐honored classical prescription for tonifying Qi, strengthening the spleen, removing dampness, and arresting diarrhea, has shown broad clinical efficacy in digestive disorders.
Jinlan Di, Xiaochun Zhang
wiley   +1 more source

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