Results 71 to 80 of about 540,444 (291)
Environment International, 2020 Fine particulate matter (PM2.5) is one of the most important components of environmental pollutants, and is associated with pulmonary injury. However, the biological mechanisms of pulmonary damage caused by PM2.5 are poorly defined, especially the ...
Meizhen Li +12 more
doaj +1 more source
Emerging role of the pentose phosphate pathway in hepatocellular carcinoma [PDF]
, 2017 In recent years, there has been a revival of interest in metabolic changes of cancer cells as it has been noticed that malignant transformation and metabolic reprogramming are closely intertwined.
Columbano, Amedeo +2 more
core +2 more sources
Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk
Advanced Healthcare Materials, EarlyView.Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor +12 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen +13 more
wiley +1 more source
Journal of Translational Medicine, 2018 Background It has been reported mesenchymal stem cells (MSCs) are recruited to and become integral parts of the tumor microenvironment. MSCs might have an active role in solid tumor progression, especially cancer metastasis.
Jing-Huan Li +4 more
doaj +1 more source
Lymphoma caused by intestinal microbiota. [PDF]
, 2014 The intestinal microbiota and gut immune system must constantly communicate to maintain a balance between tolerance and activation: on the one hand, our immune system should protect us from pathogenic microbes and on the other hand, most of the millions ...
Schiestl, Robert H, Yamamoto, Mitsuko L
core +2 more sources
The Vegan Villain Sets Out to The End of Summer: Functionalized Coatings as Biohybrid UV‐Sensors
Advanced Materials Interfaces, EarlyView.This study introduces biohybrid coatings incorporating E. coli biomass expressing photoconvertible fluorescent proteins as UV‐A responsive elements. Upon irradiation at 400 nm, the coatings exhibit an irreversible fluorescence shift from green to red within 15 min. Notably, the photoconversion capability is retained after >1 year of storage.
Amelie Skopp +3 more
wiley +1 more source
Advanced Science, EarlyView.This study has characterized a functionally distinct macrophage subset, termed CCL5hi macrophages, and elucidated the underlying mechanisms of a regulatory feedback loop that interconnects IFN‐γ, CCL5hi macrophages, and CD8+ T cells within the TME of ESCC undergoing immunochemotherapy.
Yuanzhen Ma +10 more
wiley +1 more source
De novo identification of essential protein domains from CRISPR-Cas9 tiling-sgRNA knockout screens
Nature Communications, 2019 Tiling-sgRNA designs allow the in situ evaluation of protein domain functions. Here the authors present ProTiler - a computational method to predict CRISPR knockout hyper-sensitive regions, revealing previously unannotated domains.
Wei He +11 more
doaj +1 more source
, 2015 Mechanistic multi-stage models are used to analyze lung-cancer mortality after Plutonium exposure in the Mayak-workers cohort, with follow-up until 2008.
Eidemüller, Markus +2 more
core +2 more sources