Results 71 to 80 of about 547,981 (341)
Signalling Pathways Implicated in Obesity Associated Cancers [PDF]
, 2014 Grant support: The Scottish Government's Rural and Environment Science and Analytical Services Division. Declaration of interest: The author declares that there is no conflict of interest.Peer reviewedPublisher ...
Drew, Janice E.
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FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Discover OncologyHepatocellular carcinoma (HCC) remains a global health challenge owing to its widespread incidence and high mortality. HCC has a specific immune tolerance function because of its unique physiological structure, which limits the efficacy of chemotherapy ...
Minni Zhang +5 more
doaj +1 more source
Systematic evaluation of RNA-Seq preparation protocol performance
BMC Genomics, 2019 Background RNA-Seq is currently the most widely used tool to analyze whole-transcriptome profiles. There are numerous commercial kits available to facilitate preparing RNA-Seq libraries; however, it is still not clear how some of these kits perform in ...
Hsueh-Ping Chao +13 more
doaj +1 more source
FUKUSHIMA JOURNAL OF MEDICAL SCIENCE, 2001 Colorectal carcinogenesis is a multi-step process during which genetic and epigenetic events determine the transition from a normal cell to a malignant cell. In the past decade, intensive research led to the identification of two types of colorectal cancers that are distinct by their carcinogenesis process.
T, Fukushima, S, Takenoshita
openaire +3 more sources
Lymphoma caused by intestinal microbiota. [PDF]
, 2014 The intestinal microbiota and gut immune system must constantly communicate to maintain a balance between tolerance and activation: on the one hand, our immune system should protect us from pathogenic microbes and on the other hand, most of the millions ...
Schiestl, Robert H, Yamamoto, Mitsuko L
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Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt +5 more
wiley +1 more source
Fos co-operation with PTEN loss elicits keratoacanthoma not carcinoma due to p53/p21WAF-induced differentiation triggered by GSK3b inactivation and reduced AKT activity [PDF]
, 2008 To investigate gene synergism in multistage skin carcinogenesis, the RU486-inducible cre/lox system was employed to ablate PTEN function [K14.cre/D5PTENflx] in mouse epidermis expressing activated v-fos [HK1.fos].
Alexander, C.L. +5 more
core +1 more source
Advanced Healthcare Materials, EarlyView.This study develops a dual‐bioinspired hydrogel, MSA@PGel (macrophage membrane‐coated and salvianolic acid B/5‐aminolevulinic acid co‐loaded liposomes embedded in a polydopamine‐based gel), that integrates macrophage membrane‐mediated active targeting and mussel‐inspired wet adhesion for programmed intervention in oral precancerous lesions.
Xiaoxian Zhao +8 more
wiley +1 more source
Molecular mechanisms of nickel carcinogenesis: nickel binding to histone H4 and Cap43 protein [PDF]
, 2005 The carcinogenicity of nickel compounds has been confirmed and corroborated by numerous epidemiological studies in humans and carcinogenesis bioassays in animals.
Medici, Serenella +2 more
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