Results 1 to 10 of about 113,709 (339)
Molecules, 2022 Nickel is toxic to humans. Its compounds are carcinogenic. Furthermore, nickel allergy is a severe health problem that affects approximately 10–20% of humans.
Nina E. Wezynfeld +4 more
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Nanomaterials, 2022 Iron-tannic acid nanoparticles (Fe-TA NPs) presented MRI contrast enhancement in both liver cancer cells and preneoplastic rat livers, while also exhibiting an anti-proliferative effect via enhanced autophagic death of liver cancer cells.
Chi Be Hlaing +5 more
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Cadmium, carcinogen, co-carcinogen and anti carcinogen [PDF]
Indian Journal of Clinical Biochemistry, 2001 As a stress agent, inducing apoptosis and blocking it, Cd can have both helpful and harmful effects. The atmosphere is a thin envelope which makes the worid a global village. Cd is the most toxic metal in air. As both the first and second messenger of the stress response, it is synergistically toxic with all other stressors, including many other ...
R, Chandra +3 more
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Toxicological Properties of 7-Methylguanine, and Preliminary Data on its Anticancer Activity
Frontiers in Pharmacology, 2022 7-Methylguanine (7-MG) competitively inhibits the DNA repair enzyme poly(ADP-ribose) polymerase (PARP) and RNA-modifying enzyme tRNA-guanine transglycosylase (TGT) and represents a potential anticancer drug candidate.
Kirill Kirsanov +16 more
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Final review of the Séralini <em>et al</em>. (2012a) publication on a 2-year rodent feeding study with glyphosate formulations and GM maize NK603 as published online on 19 September 2012 in Food and Chemical Toxicology [PDF]
EFSA Journal, 2012 On 19 September 2012, Séralini et al. published online in the scientific journal Food and Chemical Toxicology a publication describing a 2-year feeding study in rats investigating the health effects of genetically modified maize NK603 with and without ...
European Food Safety Authority
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Effects of Prenatal Exposure to Aflatoxin B1: A Review
Molecules, 2021 Aflatoxins are mycotoxins produced as secondary fungal metabolites. Among them, aflatoxin B1 (AFB1) stands out due to its genotoxic and mutagenic potential, being a potent initiator of carcinogenesis.
João Victor Batista da Silva +2 more
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International Journal of Occupational Medicine and Environmental Health, 2021 Objectives The aim of this study is to conduct a quantitative assessment of the risk related to occupational exposure to wood dust and the occurrence of sinonasal epithelial cancer (SNEC) by histotype, depending on the duration of exposure, using ...
Renata Soćko
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Frontiers in Public Health, 2017 Genotoxicity and carcinogenicity testing of pharmaceuticals prior to commercialization is requested by regulatory agencies. The bacterial mutagenicity test was considered having the highest accuracy of carcinogenic prediction.
Qianying Liu +7 more
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Molecules, 2022 Read-across applies the principle of similarity to identify the most similar substances to represent a given target substance in data-poor situations. However, differences between the target and the source substances exist.
Edoardo Luca Viganò +6 more
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Considerations on the applicability of OECD TG 453 to whole food/feed testing [PDF]
EFSA Journal, 2013 Upon request from the European Commission, the European Food Safety Authority prepared a scientific report that would aid the future establishment of protocols for chronic toxicity and/or carcinogenicity studies in rodents with whole food/feed.
European Food Safety Authority
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