Medium-Term Bioassay System for Detection of Carcinogens and Modifiers of Hepatocarcinogenesis Utilizing the GST-P Positive Liver Cell Focus as an Endpoint Marker [PDF]
, 1989 Nobuyuki Ito +3 more
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Environmental and Molecular Mutagenesis, EarlyView.Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl +14 more
wiley +1 more source
Beyond computational predictions: toward mechanistic validation and systemic profiling of PFOA carcinogenicity. [PDF]
Int J SurgXie L, Chen T.
europepmc +1 more source
Action of Caffeine in Altering the Carcinogen-Activating and -Detoxifying Enzymes in Mice.
, 1992 Rajinder Kaur GANDHI, K.L. Khanduja
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Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines
Environmental and Molecular Mutagenesis, EarlyView.ABSTRACT The current genotoxicity testing paradigm provides little mechanistic information, has poor specificity in predicting carcinogenicity in humans, and is not suited to assessing a large number of chemicals. Genomic technologies enable the characterization of genome‐wide transcriptional changes in response to chemical treatments that can inform ...
Heng‐Hong Li +7 more
wiley +1 more source
Pollenkitt From Narcissus tazetta: Evaluation of Its UV-Protective Potential as a Plant-Based Biomaterial Source. [PDF]
Chem BiodiversÇetinbaş-Genç A +4 more
europepmc +1 more source
A multi‐level approach for multi‐objective optimization in process eco‐design
Environmental Progress &Sustainable Energy, EarlyView.Abstract This work addresses a central challenge in process eco‐design: how to efficiently integrate environmental and economic criteria—often conflicting—into early design stages while managing the high dimensionality of Life Cycle Assessment (LCA) indicators.
Luis Fernando Morales‐Mendoza +3 more
wiley +1 more source
Analysis of the Toxicological Profile of <i>Heracleum sosnowskyi</i> Manden. Metabolites Using <i>In Silico</i> Methods. [PDF]
Plants (Basel)Rassabina AE, Fedorov MV.
europepmc +1 more source
Cytogenetic and Carcinogenic Effects of Exposure to Radiofrequency Radiation
, 2007 James P. McNamee, Pascale V. Bellier
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