Results 21 to 30 of about 113,709 (339)

Prediction of ADME-Tox properties and toxicological endpoints of triazole fungicides used for cereals protection

open access: yesADMET and DMPK, 2019
Within this study we have considered 9 triazole fungicides that are approved to be used in European Union for protecting cereals: cyproconazole, epoxiconazole, flutriafol, metconazole, paclobutrazole, tebuconazole, tetraconazole, triadimenol and ...
Ionut Mădălin Gridan   +2 more
doaj   +1 more source

Relevant Aspects of Drug Genetic Toxicology

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2022
Genotoxic lesions are not only a cause of genetic pathologies and cancer, but also the most common and significant factor of the etiopathology of cardiovascular and neurodegenerative disorders, reproductive losses, infertility, and aging.
A. D. Durnev, A. K. Zhanataev
doaj   +1 more source

Mycotoxin exposure and human cancer risk : a systematic review of epidemiological studies

open access: yes, 2020
In recent years, there has been an increasing interest in investigating the carcinogenicity of mycotoxins in humans. This systematic review aims to provide an overview of data linking exposure to different mycotoxins with human cancer risk. Publications (
Castegnaro M.   +16 more
core   +2 more sources

Study on the chronic toxicity and carcinogenicity of iron-based bioabsorbable stents

open access: yesNanotechnology Reviews, 2023
Fe-based stents have been made a figure in biodegradable stents by their good mechanical capacity and biocompatibility, appropriate strength–ductility combination. Although the iron corrosion rate was not ideal, which had been optimized by iron alloy and
Shi Xiaoli   +8 more
doaj   +1 more source

Low doses of ochratoxin A induce micronucleus formation and delay DNA repair in human lymphocytes [PDF]

open access: yes, 2014
The contamination of food commodities by fungal toxins has attracted great interest because many of these mycotoxins are responsible for different diseases, including cancer and other chronic illnesses. Ochratoxin A (OTA) is a mycotoxin naturally present
Barrón-Vivanco, Briscia S.   +9 more
core   +2 more sources

Scientific Ignorance and Reliable Patterns of Evidence in Toxic Tort Causation: Is There a Need for Liability Reform? [PDF]

open access: yes, 2001
As a first step to preserving the central aims of tort law, courts will need to recognize the wide variety of respectable, reliable patterns of evidence on which scientists themselves rely for drawing inferences about the toxicity of substances.
Cranor, Carl F., Eastmond, David A.
core   +2 more sources

Application of a developed triple-classification machine learning model for carcinogenic prediction of hazardous organic chemicals to the US, EU, and WHO based on Chinese database

open access: yesEcotoxicology and Environmental Safety, 2023
Cancer, the second largest human disease, has become a major public health problem. The prediction of chemicals’ carcinogenicity before their synthesis is crucial.
Ning Hao   +3 more
doaj   +1 more source

Chronic ethanol consumption in mice does not induce DNA damage in somatic or germ cells, evaluated by the bone marrow micronucleous assay and the dominant lethal mutation assay [PDF]

open access: yes, 2012
Indexación: Web of Science; ScieloAlthough alcohol is known to be a carcinogen for humans, ethanol-genotoxicity studies are incomplete. Ethanol seems not to be a bacterial mutagen, but the results are conflicting in rodent assays.
Ellahueñe, Manuel   +2 more
core   +1 more source

Carcinogenic Mycotoxins*

open access: yes, 2010
Mycotoxins are metabolites of molds considered to be a major risk factor affecting human and animal health. It is estimated that 25% of the world’s crop production is contaminated with mycotoxins. Mold contamination occurs extensively in fields and is particularly severe in tropical countries.
Peraica, Maja, Domijan, Ana-Marija
openaire   +2 more sources

Data Quality in Predictive Toxicology: Identification of Chemical Structures and Calculation of Chemical Descriptors [PDF]

open access: yes, 2000
Every technique for toxicity prediction and for the detection of structure–activity relationships relies on the accurate estimation and representation of chemical and toxicologic properties.
Gottmann, Eva   +3 more
core   +3 more sources

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