Results 31 to 40 of about 113,709 (339)

Dioxin levels in cattle hide processed using different fuel sources for human consumption in Sokoto Central Abattoir, Sokoto State, Nigeria

open access: yesJournal of Interventional Epidemiology and Public Health
Introduction: The practice of using tyres to singed hide has been a daily occurrence in most of the abattoirs in Nigeria including Sokoto. This practice exposes meat/hide to hazardous toxic compounds such as heavy metals, polyaromatic hydrocarbons ...
Umar Zakariyau   +5 more
doaj   +1 more source

Early and Late Onset Side Effects of Photodynamic Therapy

open access: yesBiomedicines, 2018
Photodynamic Therapy (PDT) is a non-invasive treatment successfully used for neoplastic, inflammatory and infectious skin diseases. One of its strengths is represented by the high safety profile, even in elderly and/or immuno-depressed subjects.
Francesco Borgia   +5 more
doaj   +1 more source

Carcinogenic Effects of Areca Nut and Its Metabolites: A Review of the Experimental Evidence

open access: yesClinics and Practice, 2023
Oral cancers (OC) are among the most frequent malignancies encountered in Southeast Asia, primarily due to the prevalent habit of betel quid (BQ) and smokeless tobacco use in this region.
Kalpani Senevirathna   +6 more
doaj   +1 more source

Opium Carcinogenicity: A Systematic Review of Experimental Studies

open access: yesBasic & Clinical Cancer Research, 2020
Several epidemiological studies have reported that regular use of opium can be associated with an increased risk of developing cancers, including oesophageal, laryngeal, bladder, lung, and gastric cancer.
Haniyeh Rafipour   +9 more
doaj   +1 more source

A Framework for Assessing the Rationality of Judgments in Carcinogenicity Hazard Identification [PDF]

open access: yes, 1997
Arguing that guidelines for identifying carcinogens now lack a philosophically rigorous framework, the authors present an alternative that draws clear attention to the process of reasoning towards judgments of ...
Brown, Kenneth G.   +1 more
core   +2 more sources

Cell transformation assays for prediction of carcinogenic potential: State of the science and future research needs [PDF]

open access: yes, 2011
Copyright @ 2011 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use ...
A. D. Scott   +65 more
core   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

DeepCarc: Deep Learning-Powered Carcinogenicity Prediction Using Model-Level Representation

open access: yesFrontiers in Artificial Intelligence, 2021
Carcinogenicity testing plays an essential role in identifying carcinogens in environmental chemistry and drug development. However, it is a time-consuming and label-intensive process to evaluate the carcinogenic potency with conventional 2-years rodent ...
Ting Li   +6 more
doaj   +1 more source

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead. [PDF]

open access: yes, 2015
Lifestyle factors are responsible for a considerable portion of cancer incidence worldwide, but credible estimates from the World Health Organization and the International Agency for Research on Cancer (IARC) suggest that the fraction of cancers ...
Ab Hamid, Hasiah   +173 more
core   +11 more sources

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

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