Results 81 to 90 of about 113,709 (339)

Oxidation and reduction of carcinogenic organic pollutants using ethylene glycol intercalated Fe:Cu LDH and its magnetic property [PDF]

, 2022
Sonika Panghal, Pankaj Gupta, Richa Tomar   +2 more
openalex   +1 more source

Improved Synthesis of 5-methylbenz(a)anthracene [PDF]

, 1987
A revised synthesis of 5-methylbenz(a)anthracene is reported. It involves only three simple and convenient steps starting from a commercially available compound, and gives a 82% overall yield.
Che, Jia, Yang, Dominic T.C.
core   +2 more sources

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

Identifying and Prioritizing Chemicals with Uncertain Burden of Exposure: Opportunities for Biomonitoring and Health-Related Research. [PDF]

, 2019
BackgroundThe National Institutes of Health's Environmental influences on Child Health Outcomes (ECHO) initiative aims to understand the impact of environmental factors on childhood disease. Over 40,000 chemicals are approved for commercial use.
(Environmental influences on Child Health Outcomes), Beamer, Paloma I, Bennett, Deborah H, Boyles, Rebecca R, Buckley, Jessie P, Kannan, Kurunthachalam, Pellizzari, Edo D, Wang, Aolin, Woodruff, Tracey J, Zhu, Yeyi   +9 more
core  

Hexabromocyclododecane and hexachlorocyclohexane: How lessons learnt have led to improved regulation [PDF]

, 2014
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2014 Taylor & Francis.The use of chemicals by society has many benefits but contamination of the environment is an unintended consequence.
BSEF, Cyril O. Onogbosele, Desjardins D., Drottar K.R., Drottar K.R., EC, Hunziker R.W., IPCS, IPCS, Law K., Mackay D., Mark D. Scrimshaw, Roberts C.A., Swedish Chemicals Agency, WHO   +14 more
core   +1 more source

Machine Learning for Green Solvents: Assessment, Selection and Substitution

Advanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta, Janhavi Nistane, Abhishek Sose, Harikrishna Sahu, Rampi Ramprasad   +4 more
wiley   +1 more source

Assessment of potentially toxic elements’ contamination in soil around Mohammadabad landfill, Qazvin Province [PDF]

علوم زمین خوارزمی
The aim of this study was to monitor the pollution of potentially toxic elements in the soils surrounding the Mohammadabad landfill, determine their sources, and assess health risks. 19 soil samples were collected from 11 sampling stations (including sub-
Meisam Rastegari Mehr, Fatemeh Najafi, Ata Shakeri, Leyla Abdollahbeglou   +3 more
doaj  

Prediction of the carcinogenic potential of human pharmaceuticals using repeated dose toxicity data and their pharmacological properties

Frontiers in Medicine, 2016
In an exercise designed to reduce animal use, we analysed the results of rat sub-chronic toxicity studies from 289 pharmaceutical compounds with the aim to predict the tumour outcome of carcinogenicity studies in this species.
Jan Willem Van Der Laan, Jan Willem Van Der Laan, Wenny Buitenhuis, Laura Wagenaar, Ans Soffers, Eugene van Someren, Cyrille Krul, Ruud Woutersen, Ruud Woutersen   +8 more
doaj   +1 more source

Dehydroalanine and Lysinoalanine in Thermolyzed Casein do not Promote Colon Cancer in the Rat [PDF]

, 2008
Thermolysis of proteins produces xenobiotic amino-acids such as the potentially toxic lysinoalanine, and the alkylating agent, dehydro¬alanine, which have been considered possible health hazards.
AIN, Bachmeier, Bartone, Bird, Cattaneo, Cheftel, Corpet, Corpet, Corpet, Corpet, Corpet, Corpet, Corpet, De Groot, Deng, Denis E. Corpet, D’Agostina, Finley, Friedman, Gerb er, Kleyn, Kumar, Lutz, Maga, Masri, Michael C. Archer, Parnaud, Pintauro, Sternberg, Struthers, Sugimura, Sylviane Taché, Vlassara, Vo, W. Robert Bruce, Wenzel, Zhang   +36 more
core   +3 more sources

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

Advanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang   +20 more
wiley   +1 more source