Results 21 to 30 of about 34,758 (354)

Safety assessment of the substance phosphorous acid, mixed 2,4-bis(1,1-dimethylpropyl)phenyl and 4-(1,1-dimethylpropyl)phenyl triesters for use in food contact materials [PDF]

, 2017
Publisher ...
Barthélémy, Eric, Bolognesi, Claudia, Castle, Laurence, Cravedi, Jean-Pierre, EFSA Panel on Food Contact Materials Enzymes, Flavourings and Processing Aids (CEF), Engel, Karl-Heinz, Fowler, Paul, Franz, Roland, Grob, Konrad, Gürtler, Rainer, Husøy, Trine, Kolf-Clauw, Martine, Kärenlampi, Sirpa, Lampi, Eugenia, Mennes, Wim, Milana, Maria Rosaria, Penninks, André, Silano, Vittorio, Smith, Andrew, Svensson, Kettil, Tavares Poças, Maria de Fátima, Tlustos, Christina, Wölfle, Detlef, Zorn, Holger, Zugravu, Corina-Aurelia   +24 more
core   +3 more sources

Chronic ethanol consumption in mice does not induce DNA damage in somatic or germ cells, evaluated by the bone marrow micronucleous assay and the dominant lethal mutation assay [PDF]

, 2012
Indexación: Web of Science; ScieloAlthough alcohol is known to be a carcinogen for humans, ethanol-genotoxicity studies are incomplete. Ethanol seems not to be a bacterial mutagen, but the results are conflicting in rodent assays.
Ellahueñe, Manuel, Olmedo, María Isabel, Perez-Alzola, Patricia   +2 more
core   +1 more source

Degradation of Aflatoxin B₁ in Moldy Maize by Pseudomonas aeruginosa and Safety Evaluation of the Degradation Products

Foods, 2023
Aflatoxin B1 (AFB1) is the most harmful mycotoxin commonly found in food and feed. Pollution from AFB1 causes serious economic and health issues worldwide because it causes strong mutagenicity and carcinogenicity in humans and animals.
Yanhua Xu, Renyong Zhao, Chenxi Liu
doaj   +1 more source

Permitted daily exposure for diisopropyl ether as a residual solvent in pharmaceuticals [PDF]

, 2018
Solvents can be used in the manufacture of medicinal products provided their residual levels in the final product comply with the acceptable limits based on safety data.
Evandri, Maria Grazia, Romanelli, Luca
core   +1 more source

Study on the chronic toxicity and carcinogenicity of iron-based bioabsorbable stents

Nanotechnology Reviews, 2023
Fe-based stents have been made a figure in biodegradable stents by their good mechanical capacity and biocompatibility, appropriate strength–ductility combination. Although the iron corrosion rate was not ideal, which had been optimized by iron alloy and
Shi Xiaoli, Zhang Lu, Liu Yanfen, Wang Jinyu, Zhang Gui, Qi Haiping, Zhang Wanqian, Zhang Deyuan, Wang Jin   +8 more
doaj   +1 more source

Risk assessment of di(2-ethylhexyl) phthalate in the workplace [PDF]

Environmental Health and Toxicology, 2016
Objectives A hazard assessment of di(2-ethylhexyl) phthalate (DEHP), a commonly used workplace chemical, was conducted in order to protect the occupational health of workers.
Hyeon-Yeong Kim
doaj   +1 more source

Predicting Dose-Dependent Carcinogenicity of Chemical Mixtures Using a Novel Hybrid Neural Network Framework and Mathematical Approach

Toxics, 2023
This study addresses the challenge of assessing the carcinogenic potential of hazardous chemical mixtures, such as per- and polyfluorinated substances (PFASs), which are known to contribute significantly to cancer development.
Sarita Limbu, Sivanesan Dakshanamurthy
doaj   +1 more source

An Ensemble Model of QSAR Tools for Regulatory Risk Assessment [PDF]

, 2016
Quantitative structure activity relationships (QSARs) are theoretical models that relate a quantitative measure of chemical structure to a physical property or a biological effect.
Merrill, Stephen, Povinelli, Richard J., Pradeep, Prachi, White, Shannon   +3 more
core   +4 more sources

Two-year intermittent exposure of a multiwalled carbon nanotube by intratracheal instillation induces lung tumors and pleural mesotheliomas in F344 rats

Particle and Fibre Toxicology, 2022
Background A mounting number of studies have been documenting the carcinogenic potential of multiwalled carbon nanotubes (MWCNTs); however, only a few studies have evaluated the pulmonary carcinogenicity of MWCNTs in vivo.
Motoki Hojo, Ai Maeno, Yoshimitsu Sakamoto, Aya Ohnuki, Yukie Tada, Yukio Yamamoto, Kiyomi Ikushima, Ryota Inaba, Jin Suzuki, Yuhji Taquahashi, Satoshi Yokota, Norihiro Kobayashi, Makoto Ohnishi, Yuko Goto, Takamasa Numano, Hiroyuki Tsuda, David B. Alexander, Jun Kanno, Akihiko Hirose, Akiko Inomata, Dai Nakae   +20 more
doaj   +1 more source

Alternative Models for Carcinogenicity Testing [PDF]

Toxicological Sciences, 2001
The International Conference on Harmonisation Expert Working Group on Safety suggested that under certain circumstances, data from alternative assays could be used in safety evaluation in place of a second bioassay. Several alternatives were discussed.
S M, Cohen, D, Robinson, J, MacDonald
openaire   +2 more sources