Using the Key Characteristics of Carcinogens to Develop Research on Chemical Mixtures and Cancer
Background: People are exposed to numerous chemicals throughout their lifetimes. Many of these chemicals display one or more of the key characteristics of carcinogens or interact with processes described in the hallmarks of cancer.
C. Rider+9 more
semanticscholar +1 more source
Application of the Key Characteristics of Carcinogens to Per and Polyfluoroalkyl Substances
Per- and polyfluoroalkyl substances (PFAS) constitute a large class of environmentally persistent chemicals used in industrial and consumer products. Human exposure to PFAS is extensive, and PFAS contamination has been reported in drinking water and food
A. Temkin+4 more
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Supervised mutational signatures for obesity and other tissue-specific etiological factors in cancer
Determining the etiologic basis of the mutations that are responsible for cancer is one of the fundamental challenges in modern cancer research. Different mutational processes induce different types of DNA mutations, providing ‘mutational signatures ...
Bahman Afsari+12 more
doaj +1 more source
Cell transformation assays for prediction of carcinogenic potential: State of the science and future research needs [PDF]
Copyright @ 2011 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use ...
A. D. Scott+65 more
core +2 more sources
Objectives This study provides a detailed analysis of the global and regional burden of cancer due to occupational carcinogens from the Global Burden of Disease 2016 study.
Tim Lesley Kyle Sally Kurt Degu Omar Dilaram Mohsen Fa Driscoll Rushton Steenland Hutchings Straif Abate
semanticscholar +1 more source
Inequalities in Environmental Cancer Risk and Carcinogen Exposures: A Scoping Review
Background: Cancer is the leading cause of death in Canada and a major cause of death worldwide. Environmental exposure to carcinogens and environments that may relate to health behaviors are important to examine as they can be modified to lower cancer ...
Kristian Larsen+2 more
semanticscholar +1 more source
Risk assessment, and carcinogen mutagen for workers potentially exposed in the research laboratories of “Sapienza” University of Rome for Health Surveillance [PDF]
The following work is meant to represent the evaluation of risk factors for the health of exposed workers, arising from the management of carcinogenic and mutagenic substances, through the use of algorithms.
Altrudo, Paola+4 more
core +2 more sources
Introduction Although myelodysplastic syndrome (MDS), acute myeloid leukemia (AML), myeloproliferative neoplasms (MPN) – including chronic myeloid leukemia (CML) – and myelodysplastic/myeloproliferative neoplasms (MDS/MPN) are largely clinically distinct
K. A. Mundt+7 more
doaj +1 more source
The Failure of Agency-Forcing: The Regulation of Airborne Carcinogens Under Section 112 of the Clean Air Act [PDF]
Professor Graham analyzes section 112 of the Clean Air Act, a provision intended by Congress to achieve ambitious regulatory ends by constraining agency discretion.
Graham, John D.
core +2 more sources
Updated fraction of cancer attributable to lifestyle and environmental factors in Denmark in 2018
Environmental exposures and avoidable risk factors account for a large proportion of cancer burden. Exposures and lifestyle vary over time and between populations, which calls for updated and population-specific quantification of how various avoidable ...
Anne Julie Tybjerg+5 more
doaj +1 more source