Results 41 to 50 of about 3,679,735 (330)

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

Proceedings of the National Academy of Sciences of the United States of America, 1975
About 300 carcinogens and non-carcinogens of a wide variety of chemical types have been tested for mutagenicity in the simple Salmonella/microsome test.
J. McCann, E. Choi, E. Yamasaki, B. Ames
semanticscholar   +1 more source

Genetic Reprogramming of Human Mammary Cells by Environmental Carcinogens Released into Breast Milk

CHIMIA, 2008
Epidemiologic studies indicate that high serum levels of chlorinated pollutants such as dioxins or pesticides constitute a risk factor for breast cancer in postmenopausal women.
Ramiro Dip, Tonko Buterin, Daniela Wenger, Peter Schmid, Hanspeter Naegeli   +4 more
doaj   +1 more source

Risk-based indicators of Canadians’ exposures to environmental carcinogens

Environmental Health, 2013
BackgroundTools for estimating population exposures to environmental carcinogens are required to support evidence-based policies to reduce chronic exposures and associated cancers.
Eleanor M. Setton, P. Hystad, Karla Poplawski, Roslyn Cheasley, Alejandro Cervantes-Larios, C. P. Keller, P. Demers   +6 more
semanticscholar   +1 more source

OccIDEAS: An Innovative Tool to Assess Past Asbestos Exposure in the Australian Mesothelioma Registry

Safety and Health at Work, 2012
Malignant mesothelioma is an uncommon but rapidly fatal disease for which the principal aetiological agent is exposure to asbestos. Mesothelioma is of particular significance in Australia where asbestos use was very widespread from the 1950s until the ...
Ewan MacFarlane, Geza Benke, Malcolm R. Sim, Lin Fritschi   +3 more
doaj   +1 more source

Carcinogens and DNA damage

Biochemical Society Transactions, 2018
Humans are variously and continuously exposed to a wide range of different DNA-damaging agents, some of which are classed as carcinogens. DNA damage can arise from exposure to exogenous agents, but damage from endogenous processes is probably far more ...
Jessica L. Barnes, M. Zubair, Kaarthik John, M. Poirier, F. Martin   +4 more
semanticscholar   +1 more source

Histone deacetylases (HDACs) in XPC gene silencing and bladder cancer

Journal of Hematology & Oncology, 2011
Bladder cancer is one of the most common malignancies and causes hundreds of thousands of deaths worldwide each year. Bladder cancer is strongly associated with exposure to environmental carcinogens.
Abrams Judith, Wang Le, Xu Xiaoxin S, Wang Gan   +3 more
doaj   +1 more source

Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis

Environmental Health Perspectives, 2015
Background: A recent review by the International Agency for Research on Cancer (IARC) updated the assessments of the > 100 agents classified as Group 1, carcinogenic to humans (IARC Monographs Volume 100, parts A–F).
Martyn T. Smith, K. Guyton, C. Gibbons, Jason M Fritz, C. Portier, I. Rusyn, D. DeMarini, J. Caldwell, R. Kavlock, P. Lambert, S. Hecht, J. Bucher, B. Stewart, R. Baan, V. Cogliano, K. Straif   +15 more
semanticscholar   +1 more source

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead. [PDF]

, 2015
Lifestyle factors are responsible for a considerable portion of cancer incidence worldwide, but credible estimates from the World Health Organization and the International Agency for Research on Cancer (IARC) suggest that the fraction of cancers ...
Ab Hamid, Hasiah, Abd Hamid, Roslida, Ahmed, Nuzhat, Al-Mulla, Fahd, Al-Temaimi, Rabeah, Ali, Abdul Manaf, Amedei, Amedeo, Andrade-Vieira, Rafaela, Azqueta, Amaya, Baglole, Carolyn J., Barclay, Barry J., Bay, Sarah N., Berg, Arthur, Bisson, William H., Blanco-Aparicio, Carmen, Brooks, Samira A., Brown, Dustin G., Brunborg, Gunnar, Calaf, Gloria M., Carlin, Danielle J., Carnero, Amancio, Carpenter, David O., Casey, Stephanie C., Castellino, Robert C., Chapellier, Marion, Charles, Amelia K., Chen, Tao, Chen, Zhenbang, Cheng, Qiang (Shawn), Chiaradonna, Ferdinando, Christopher, Joseph A., Cohen-Solal, Karine A., Colacci, Annamaria, Collins, Andrew R., Corsini, Emanuela, Cruickshanks, Nichola, Curran, Colleen S., D'Abronzo, Leandro S., Darbre, Philippa, Darroudi, Firouz, de Cerain Salsamendi, Adela Lopez, Decker, William K., Dent, Paul, Di Fiore, Riccardo, Dong, Chenfang, Dormoy, Valerian, Dornetshuber-Fleiss, Rita, Eltom, Sakina, Engstrom, Wilhelm, Eriksson, Staffan, Felsher, Dean W., Fernando Martinez-Leal, Juan, Forte, Stefano, Ghosh, Paramita M., Gilbertson, Michael, Goldberg, Gary S., Gonzalez, Laetitia, Gonzalez, Michael J., Goodson, William H, Guarnieri, Tiziana, Gulliver, Linda, Harris, Shelley A., Heneberg, Petr, Hsu, Chia-Wen, Hsu, Hsue-Yin, Hu, Zhiwei, Hultman, Tove, III, Jian, Le, Karamouzis, Michalis V., Khatami, Mahin, Kirsch-Volders, Micheline, Klaunig, James E., Kleinstreuer, Nicole, Koch, Daniel C., Kondoh, Hiroshi, Koppen, Gudrun, Koturbash, Igor, Kravchenko, Julia, Krishnakumar, P. K., Krishnan, Harini, Kuemmerle, Nancy B., Laconi, Ezio, Laird, Dale W., Langie, Sabine A. S., Lasfar, Ahmed, Lee, Tae-Jin, Leung, Po Sing, Leyns, Luc, Li, Lin, Lin, Liang-Tzung, Lleonart, Matilde, Lowe, Leroy, Luanpitpong, Sudjit, Luqmani, Yunus, Lyerly, H. Kim, Maguer-Satta, Veronique, Manjili, Masoud H., Marignani, Paola A., Marongiu, Fabio, Martin, Francis L., Massfelder, Thierry, McCawley, Lisa J., Mehta, Rekha, Memeo, Lorenzo, Miousse, Isabelle R., Mondello, Chiara, Moon, Eun-Yi, Moorwood, Kim, Nahta, Rita, Nangami, Gladys, Nangia-Makker, Pratima, Narayanan, Kannan Badri, Naus, Christian C., Ochieng, Josiah, Odero-Marah, Valerie, Ogunkua, Olugbemiga, Olsen, Ann-Karin, Ostrosky-Wegman, Patricia, Otsuki, Takemi, Palorini, Roberta, Papagerakis, Silvana, Park, Hyun Ho, Pavanello, Sofia, Ponce-Cusi, Richard, Prudhomme, Kalan R., Raju, Jayadev, Rathmell, W. Kimryn, Ratovitski, Edward, Robey, R. Brooks, Rojanasakul, Yon, Rojas, Emilio, Roman, Jesse, Romano, Maria Fiammetta, Romano, Simona, Roy, Debasish, Roy, Rabindra, Ryan, Elizabeth P., Ryeom, Sandra, Sabbisetti, Venkata, Salem, Hosni K., Salzberg, Anna C., Sanderson, Thomas, Scovassi, A. Ivana, Singh, Neetu, Sinha, Ranjeet K., Sone, Hideko, Soucek, Laura, Sun, Jun, Thompson, Patricia, Vaccari, Monica, Vadgama, Pankaj, Valverde, Mahara, van Larebeke, Nik, Van Schooten, Frederik J., Vento, Renza, Vermeulen, Louis, Vondracek, Jan, Wade, Mark, Wagemaker, Gerard, Ward, Andrew, Weisz, Judith, Whitfield, Jonathan R., Williams, Graeme, Williams, Marc A., Wise, John Pierce, Sr., Wise, Sandra S., Wolf, Gregory T., Woodrick, Jordan, Xia, Menghang, Yasaei, Hemad, Yedjou, Clement, Zhang, Luoping, Zhou, Binhua P.   +173 more
core   +11 more sources

Cytochrome P450 CYP1A1: wider roles in cancer progression and prevention

BMC Cancer, 2009
CYP1A1 is one of the main cytochrome P450 enzymes, examined extensively for its capacity to activate compounds with carcinogenic properties. Continuous exposure to inhalation chemicals and environmental carcinogens is thought to increase the level of ...
Tsatsakis Aristidis M, Androutsopoulos Vasilis P, Spandidos Demetrios A   +2 more
doaj   +1 more source

Mutations in pathways depending on BRCA1 and BRCA2 may increase cancer risks from an environmental carcinogen [PDF]

, 2011
Recently, the President’s Cancer Panel [2008-2009] protested that preventive action is not taken when uncertainty exists about potential harm from a chemical, because the US regulatory approach demands that a hazard be incontrovertibly ...
Bernard Friedenson
core   +2 more sources