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The carcinogenicity of ciclosporin
Toxicology, 1992Experimental data relevant for the evaluation of the carcinogenic potential of the immunosuppressant ciclosporin are reviewed: Firstly, the mode of action of ciclosporin at the level of lymphocyte gene transcription, secondly, the main adverse effects especially nephrotoxicity and thirdly, the results of the chronic bioassays. The experimental data are
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The carcinogenicity of pesticides
1973The growing public concern in this country regarding the widespread existence of pesticides in the environment has reached an unprecedented level in recent years. This concern relates to (1) the possible damaging effects of pesticides on human health and (2) the problems of environmental contamination.
W W, Kilgore, M Y, Li
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The carcinogenicity of acrylamide
Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2005Acrylamide is carcinogenic to experimental mice and rats, causing tumors at multiple organ sites in both species when given in drinking water or by other means. In mice, acrylamide increases the incidence of alveologenic lung tumors and initiates skin tumors after dermal exposures.
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Journal of Agricultural and Food Chemistry, 2008
The induction of cancer by chemicals is a multiple-stage process. Acrylamide is carcinogenic to experimental mice and rats, causing tumors at multiple organ sites in both species when given in drinking water or by other means. In mice, acrylamide increased the incidence and multiplicity of lung tumors and skin tumors.
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The induction of cancer by chemicals is a multiple-stage process. Acrylamide is carcinogenic to experimental mice and rats, causing tumors at multiple organ sites in both species when given in drinking water or by other means. In mice, acrylamide increased the incidence and multiplicity of lung tumors and skin tumors.
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