Results 281 to 290 of about 352,926 (358)

Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The current genotoxicity testing paradigm provides little mechanistic information, has poor specificity in predicting carcinogenicity in humans, and is not suited to assessing a large number of chemicals. Genomic technologies enable the characterization of genome‐wide transcriptional changes in response to chemical treatments that can inform ...
Heng‐Hong Li   +7 more
wiley   +1 more source

Probiotics and Cancer: Mechanistic Insights and Organ-Specific Impact. [PDF]

open access: yesBiomolecules
Ahmad MF   +10 more
europepmc   +1 more source

Transferability, Reproducibility and Sensitivity of Mutation Quantification by Duplex Sequencing

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
ABSTRACT Duplex Sequencing (DS) is an ultra‐accurate, error‐corrected next generation sequencing (ecNGS) technology for mutation analysis. A working group (WG) within Health and Environmental Sciences Institute's Genetic Toxicology Technical Committee is investigating the suitability of ecNGS for regulatory mutagenicity testing, using DS as a model ...
Shaofei Zhang   +23 more
wiley   +1 more source

Critical Evaluation of Methods for the Identification of Aneugens

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The genotoxic potential of chemicals must be evaluated in regulatory safety assessment settings, including but not limited to, the development of new pharmaceuticals, industrial chemicals, food and cosmetic ingredients, and agrochemicals. Initial assessment of the chromosome‐damaging potential of chemicals is often conducted in mammalian cells
Xiaowen Sun   +8 more
wiley   +1 more source

Photo‐Electrodialysis for Brackish Water Desalination: A Life Cycle Sustainability Assessment from Experimental Insights

open access: yesEnergy Technology, EarlyView.
This study explores the integration of solar energy with electrodialysis (ED) for sustainable freshwater generation. A photoactive electrode enhances ion transport, reducing external energy inputs and environmental impacts compared to conventional ED.
Namra Mir, Burak Yuzer, Yusuf Bicer
wiley   +1 more source

Does Occupational Exposure to Chemicals/Carcinogens Affect the Hematological Parameters of Workers? [PDF]

open access: yesJ Clin Med
La Torre G   +10 more
europepmc   +1 more source

Fabrication of Organic Solar Cells from Surfactant‐Free Aqueous Nanoparticle Dispersions

open access: yesEnergy Technology, EarlyView.
This study develops water‐based nanoparticle dispersions of P3HT:PC71BM for the fabrication of organic bulk‐heterojunction solar cells, eliminating toxic solvents and stabilizing surfactants. Co‐solvents are used to improve wetting. The resulting solar cells achieve power conversion efficiencies of 2.7% and demonstrate excellent long‐term stability ...
Karen Fischer   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy