Results 41 to 50 of about 131,797 (241)
FEBS Open Bio, EarlyView.Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei +7 more
wiley +1 more source
Cancer in Ancient Human Populations: Methods and Practice in Bioarchaeology and Paleopathology [PDF]
, 2020 Best Undergraduate Writing in Anthropology Award, 2019-2020Despite its prevalence in contemporary public health, research on the paleopathology of cancer is still extremely limited.
Gardner, Elijah
core
Aging and Cancer, EarlyView.Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley +1 more source
The Normative Nature of Risk Assessment: Features and Possibilities [PDF]
, 1997 Dr. Cranor argues that appreciating risk assessment to be permeated with normative presuppositions, in contrast with being primarily objective, opens up unforeseen possibilities for risk ...
Cranor, Carl F.
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The Regulation of Trace Metal Elements in Cancer Ferroptosis
Advanced Biology, EarlyView.The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang +5 more
wiley +1 more source
Regulating Air Toxics in Rhode Island: Policy vs. Technical Decisions [PDF]
, 1991 Dr. Roqu6 recounts her work as a doctoral candidate at Brown in developing standards for the regulation of airborne carcinogens. Based in part on this experience, she argues that care needs be taken lest those who regulate Risk bury key policy decisions ...
Roque, Julie A.
core +1 more source
, 2017 Liver fluke infections occur in people worldwide. In some low-income regions, a combination of ecological, agricultural, and culinary factors leads to a very high prevalence of infection but, in higher-income regions, infections are uncommon.
Harrington, David +2 more
core +1 more source
Multi‐Scaled Cellulosic Nanonetworks from Tunicates
Advanced Functional Materials, EarlyView.Microbial and plant nanonetworks of cellulose have enabled a wide range of high‐performance yet sustainable materials. Herein, a third class of cellulosic nanonetworks is showcased by exploiting the only animal tissue‐producing cellulose nanofibers, i.e., ascidians. An ultrastructure including spherical cells and a microvasculature with diameters of 50–
Mano Govindharaj +10 more
wiley +1 more source
Science Courts, Evidentiary Procedures and Mixed Science-Policy Decisions [PDF]
, 1993 This paper analyzes the potential for science courts to address the social need to regulate human carcinogens and concludes that, on balance, it is not high.
Cranor, Carl F.
core +1 more source
Air quality in the Industrial Heartland of Alberta, Canada and potential impacts on human health. [PDF]
, 2013 The "Industrial Heartland" of Alberta is Canada's largest hydrocarbon processing center, with more than 40 major chemical, petrochemical, and oil and gas facilities. Emissions from these industries affect local air quality and human health.
Barletta, Barbara +5 more
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