Results 41 to 50 of about 352,926 (358)

Biological Water Dynamics and Entropy: A Biophysical Origin of Cancer and Other Diseases

open access: yesEntropy, 2013
This paper postulates that water structure is altered by biomolecules as well as by disease-enabling entities such as certain solvated ions, and in turn water dynamics and structure affect the function of biomolecular interactions.
Stephanie Seneff   +2 more
doaj   +1 more source

Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?

open access: yesMolecular Oncology, EarlyView.
 
Chen‐xi Li, Zhong‐cheng Gong
wiley   +1 more source

Arsenic Methyltransferase and Methylation of Inorganic Arsenic

open access: yesBiomolecules, 2020
Arsenic occurs naturally in the environment, and exists predominantly as inorganic arsenite (As (III) and arsenate As (V)). Arsenic contamination of drinking water has long been recognized as a major global health concern. Arsenic exposure causes changes
Nirmal K. Roy, Anthony Murphy, Max Costa
doaj   +1 more source

A Framework for Assessing the Rationality of Judgments in Carcinogenicity Hazard Identification [PDF]

open access: yes, 1997
Arguing that guidelines for identifying carcinogens now lack a philosophically rigorous framework, the authors present an alternative that draws clear attention to the process of reasoning towards judgments of ...
Brown, Kenneth G.   +1 more
core   +2 more sources

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

Processed Meat and Colorectal Cancer: A Review of Epidemiologic and Experimental Evidence [PDF]

open access: yes, 2008
Processed meat intake may be involved in the etiology of colorectal cancer, a major cause of death in affluent countries. The epidemiologic studies published to date conclude that the excess risk in the highest category of processed meat-eaters is ...
Corpet, Denis E.   +2 more
core   +4 more sources

Environmental Exposures during Puberty: Window of Breast Cancer Risk and Epigenetic Damage. [PDF]

open access: yes, 2020
During puberty, a woman's breasts are vulnerable to environmental damage ("window of vulnerability"). Early exposure to environmental carcinogens, endocrine disruptors, and unhealthy foods (refined sugar, processed fats, food additives) are hypothesized ...
Aljaber, Dana   +19 more
core   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

open access: yesAdvanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang   +5 more
wiley   +1 more source

Hygienic assessment of carcinogenic health risks associated with contamination of depositing media with heavy metals

open access: yesAnaliz Riska Zdorovʹû, 2022
In nature there are depositing media which are relatively stable macrosystems. Their contamination that occurs due to long-term exposure to contaminants influences population health and this is especially vital for urbanized territories with large city ...
V.M. Boev   +4 more
doaj   +1 more source

Retrospective on U.S. Health Risk Assessment: How Others Can Benefit [PDF]

open access: yes, 1995
Dr. Paustenbach reviews the scientific underpinnings of about twenty years of health risk assessment practice and their implications for environmental policy.
Paustenbach, Dennis J.
core   +1 more source

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