Results 81 to 90 of about 352,926 (358)

Life Cycle Assessment of Magnesium‐Impregnated Biochar Production and its Application for Nutrient Removal and Soil Improvement in Rice Cultivation

open access: yesAdvanced Sustainable Systems, EarlyView.
This study evaluates the environmental trade‐offs of different rice husk management strategies using a life cycle assessment (LCA) approach. It compares biochar production for water treatment and soil improvement with direct incineration for energy generation.
José Lugo‐Arias   +7 more
wiley   +1 more source

Understanding miR‐200c: an Important Player in Resistance to Cancer Treatment

open access: yesAdvanced Therapeutics, EarlyView.
How can one microRNA alter cancer's response to therapy? miR‐200c plays a central role in therapeutic resistance by modulating epithelial‐mesenchymal transition, apoptosis, cancer stemness features, and drug efflux. This review outlines the context‐dependent functions of miR‐200c in various cancers and highlights its potential as both a biomarker and a
Fatma Sanli, Omer Faruk Karatas
wiley   +1 more source

Exploring AAV‐Mediated Gene Therapy for Inner Ear Diseases: from Preclinical Success to Clinical Potential

open access: yesAdvanced Science, EarlyView.
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu   +7 more
wiley   +1 more source

A population-based study of glutathione-S-transferase M1, T1 and P1 genotypes [PDF]

open access: yes, 2008
A retrospective study on healthy, unrelated subjects was conducted in order to estimate population glutathione-S-transferases (GST) genotype frequencies in Slovak population of men and compare our results with already published data (GSEC project)^1^.
Duš   +6 more
core   +1 more source

The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges

open access: yesAdvanced Science, EarlyView.
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li   +3 more
wiley   +1 more source

Real‐Time Evolutionary Landscape of the Bronchial Epithelium and Corresponding Dynamic Immune Cell Alterations in Lung Squamous Cell Carcinogenesis

open access: yesAdvanced Science, EarlyView.
Lung squamous cell carcinoma (LUSC) is often preceded by sequential premalignant lesions with an increasing probability of malignant progression. Using single‐cell RNA sequencing, the dynamic cellular evolution from normal lung to LUSC tissues is delineated; clonal structure of premalignant and malignant epithelium is reveled; the conversion of immune ...
Baohong Luo   +16 more
wiley   +1 more source

Science Courts, Evidentiary Procedures and Mixed Science-Policy Decisions [PDF]

open access: yes, 1993
This paper analyzes the potential for science courts to address the social need to regulate human carcinogens and concludes that, on balance, it is not high.
Cranor, Carl F.
core   +1 more source

The Carcinogenic Example

open access: yesLogic Journal of IGPL, 1997
A new kind of models for propositional linear logic (IE-models) based on commutative monoids is defined. In the author's opinion they reflect the resource interpretation better than other type of models. IE-models are sound but not complete, since they verify distributivity of \(\&\) over \(\oplus\).
openaire   +4 more sources

An integrated in vitro carcinogenicity test that distinguishes between genotoxic carcinogens, non-genotoxic carcinogens, and non-carcinogens [PDF]

open access: yesMutagenesis
Abstract Chemical safety testing plays a crucial role in product and pharmacological development, as well as chemoprevention; however, in vitro genotoxicity safety tests do not always accurately predict the chemicals that will be in vivo carcinogens.
Katherine E Chapman   +5 more
openaire   +3 more sources

PROS1‐MERTK Axis Drives Tumor Microenvironment Crosstalk and Progression in Papillary Thyroid Microcarcinoma

open access: yesAdvanced Science, EarlyView.
Identifying biomarkers associated with PTC, particularly those related to PTMC progression, is crucial for precise risk stratification and treatment planning. This study utilized single‐cell RNA sequencing on 19 surgical tissue specimens, confirmed PROS1/MERTK axis as a critical component of the cellular microenvironment and a key regulatory mechanism ...
Wenqian Zhang   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy