Results 81 to 90 of about 372,123 (339)

Genotype identification of the Human Papilloma Virus in cervicouterine lesions carrier patients

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2016
Background: during the last years there has been a high prevalence of women infected with genotypes of the human papilloma virus, considered as a high risk because of its high oncogenicity.Objective: to identify the genotypes of the human papilloma virus
Alexander Morales Fontaine   +3 more
doaj  

Book Reviews [PDF]

open access: yes, 1990
Reviews of the following books prepared by the editors of Risk on the topic of toxic tort litigation and/or public regulation of toxic substances: Frank B.
RISK Editorial Board
core   +1 more source

Cell transformation assays for prediction of carcinogenic potential: State of the science and future research needs [PDF]

open access: yes, 2011
Copyright @ 2011 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use ...
A. D. Scott   +65 more
core   +2 more sources

Lactylation Enhances the Activity of Lactate Dehydrogenase A and Promotes the Chemoresistance to Cisplatin Through Facilitating DNA Nonhomologous End Junction in Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Lactylation, linked to glycolysis, is poorly understood in regulation. It is found that LDHA is lactylated at Lys81/Lys318 by AARS1, boosting its activity and cellular lactylation via positive feedback in LUAD. Lactylation regulates NHEJ‐related proteins; their delactylation impairs NHEJ and increases cisplatin sensitivity, offering anticancer insights.
Jizhuo Li   +11 more
wiley   +1 more source

Cannabis and tobacco smoke are not equally carcinogenic

open access: yesHarm Reduction Journal, 2005
More people are using the cannabis plant as modern basic and clinical science reaffirms and extends its medicinal uses. Concomitantly, concern and opposition to smoked medicine has occurred, in part due to the known carcinogenic consequences of smoking ...
Melamede Robert
doaj   +1 more source

Comparative cytotoxicity study of nicotine and cotinine on MRC-5 cell line [PDF]

open access: yes, 2018
Nicotine has several health hazards regarding carcinogenic potential. It also imparts increased risk for respiratory, cardiovascular, and gastrointestinal disorders.
Baconi, Daniela Luiza   +4 more
core   +4 more sources

Smoking‐Induced STC2+ Tumor Cells Drive Tumor‐Vascular Crosstalk in Laryngeal Squamous Cell Carcinoma via Spatial and Single‐Cell Transcriptomics

open access: yesAdvanced Science, EarlyView.
This study identifies a smoking‐induced mechanism in LSCC whereby nicotine activates the CHRNA5–JAK2/STAT3 axis to drive STC2 transcription. STC2 upregulates TGFBI, which interacts with endothelial ITGA5 to regulate vascular permeability and promote metastasis.
Yujie Shen   +5 more
wiley   +1 more source

Biological Water Dynamics and Entropy: A Biophysical Origin of Cancer and Other Diseases

open access: yesEntropy, 2013
This paper postulates that water structure is altered by biomolecules as well as by disease-enabling entities such as certain solvated ions, and in turn water dynamics and structure affect the function of biomolecular interactions.
Stephanie Seneff   +2 more
doaj   +1 more source

Environmental Toxicology: The legacy of Silent Spring [PDF]

open access: yes, 2004
The transcript of a Witness Seminar held by the Wellcome Trust Centre for the History of Medicine at UCL, London, London, on 12 March 2002. First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2004.©The Trustee of the Wellcome
Christie, DA, Tansey, EM
core  

Mapping the Human Exposome to Uncover the Causes of Breast Cancer. [PDF]

open access: yes, 2019
Breast cancer is an important cause of morbidity and mortality for women, yet a significant proportion of variation in individual risk is unexplained. It is reasonable to infer that unexplained breast cancer risks are caused by a myriad of exposures and ...
Bessonneau, Vincent, Rudel, Ruthann A
core   +2 more sources

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