Results 11 to 20 of about 2,051,186 (321)

A global view of hepatocellular carcinoma: trends, risk, prevention and management

open access: yesNature Reviews Gastroenterology and Hepatology, 2019
Hepatocellular carcinoma (HCC) is the fourth most common cause of cancer-related death worldwide. Risk factors for HCC include chronic hepatitis B and hepatitis C, alcohol addiction, metabolic liver disease (particularly nonalcoholic fatty liver disease)
, Pierre Hainaut, Gregory J Gores
exaly   +2 more sources

Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma

open access: yesCell, 2017
SUMMARY Liver cancer has the second highest worldwide cancer mortality rate and has limited therapeutic options. We analyzed 363 hepatocellular carcinoma (HCC) cases by whole exome sequencing and DNA copy number analyses, and 196 HCC also by DNA ...
Adrian Ally   +2 more
exaly   +2 more sources

Precision treatment in advanced hepatocellular carcinoma

open access: yesCancer Cell
The past decade has witnessed significant advances in the systemic treatment of advanced hepatocellular carcinoma (HCC). Nevertheless, the newly developed treatment strategies have not achieved universal success and HCC patients frequently exhibit ...
Haigang Geng   +2 more
exaly   +2 more sources

Hepatocellular carcinoma [PDF]

open access: yesCurrent Treatment Options in Oncology, 2000
Early detection of hepatocellular carcinoma (HCC) is feasible, particularly in patients known to be at risk from chronic hepatitis and chronic liver disease. The optimal surveillance strategy is unknown. HCC usually presents as an incurable disease even when detected on surveillance. Surgical resection is the treatment of choice, but the coexistence of
LENCIONI, RICCARDO ANTONIO   +2 more
  +18 more sources

Hepatocellular carcinoma [PDF]

open access: yesNature Reviews Disease Primers, 1998
Liver cancer remains a global health challenge, with an estimated incidence of >1 million cases by 2025. Hepatocellular carcinoma (HCC) is the most common form of liver cancer and accounts for ~90% of cases. Infection by hepatitis B virus and hepatitis C virus are the main risk factors for HCC development, although non-alcoholic steatohepatitis ...
J. Llovet   +9 more
semanticscholar   +8 more sources

Hepatocellular carcinoma [PDF]

open access: yesAnales del Sistema Sanitario de Navarra, 2016
Liver cancer is the second leading cause of cancer-related deaths globally and has an incidence of approximately 850,000 new cases per year. Hepatocellular carcinoma (HCC) represents approximately 90% of all cases of primary liver cancer. The main risk factors for developing HCC are well known and include hepatitis B and C virus infection, alcohol ...
Llovet, Josep M.   +6 more
  +9 more sources

Hepatocellular carcinoma [PDF]

open access: yesCurrent Opinion in Gastroenterology, 2001
The number of papers published regarding hepatocellular carcinoma between 1999 and 2001 increased from previous years. This year a study confirmed the increase in incidence in the United States. Also, several studies established for the first time that tobacco smoking was a risk factor for the development of this tumor. Several studies established that
M M, Chokshi, J A, Marrero
  +7 more sources

CD58 acts as a tumor promotor in hepatocellular carcinoma via activating the AKT/GSK-3β/β-catenin pathway

open access: yesJournal of Translational Medicine, 2023
Background Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies worldwide because of rapid progression and high incidence of metastasis or recurrence.
Chuanzheng Wang   +7 more
doaj   +1 more source

Resveratrol protects against chronic alcohol-induced liver disease in a rat model

open access: yesSTEMedicine, 2022
Hepatic ethanol metabolism participates in the pathogenesis of alcoholic liver disease (ALD). We aimed to evaluate the protecting effects and underlying mechanisms of Resveratrol against ALD.
Hanzhang Zhu   +3 more
doaj   +1 more source

AASLD Practice Guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma

open access: yesHepatology, 2023
for End-Stage Liver Disease;
A. Singal   +15 more
semanticscholar   +1 more source

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