Results 21 to 30 of about 2,051,186 (321)
Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma.
New England Journal of Medicine, 2020 BACKGROUND The combination of atezolizumab and bevacizumab showed encouraging antitumor activity and safety in a phase 1b trial involving patients with unresectable hepatocellular carcinoma. METHODS In a global, open-label, phase 3 trial, patients with
R. Finn +20 more
semanticscholar +1 more source
Tremelimumab plus Durvalumab in Unresectable Hepatocellular Carcinoma.
NEJM Evidence, 2022 Tremelimumab/Durvalumab for Hepatocellular CarcinomaThis trial examined overall survival (OS) with tremelimumab plus durvalumab, durvalumab alone, or sorafenib in untreated patients with hepatocellular cancer who were not candidates for locoregional ...
G. Abou-Alfa +30 more
semanticscholar +1 more source
Journal of Hepatology, 2021 BACKGROUND & AIMS IMbrave150 demonstrated significantly improved overall survival (OS) and progression-free survival (PFS) with atezolizumab plus bevacizumab vs sorafenib in patients with unresectable hepatocellular carcinoma at the primary analysis ...
A. Cheng +18 more
semanticscholar +1 more source
Hepatocellular Carcinoma [PDF]
Cold Spring Harbor Perspectives in Medicine, 2015 The hepatitis B virus (HBV) is a widespread human pathogen that causes liver inflammation, cirrhosis, and hepatocellular carcinoma (HCC). Recent sequencing technologies have refined our knowledge of the genomic landscape and pathogenesis of HCC, but the mechanisms by which HBV exerts its oncogenic role remain controversial.
Marie-Annick, Buendia +1 more
openaire +2 more sources
Heat shock protein HSPA13 promotes hepatocellular carcinoma progression by stabilizing TANK
Cell Death Discovery, 2023 HSPA13, an important member of the heat shock protein family, plays an essential role in the oncogenesis of many organs, but the mechanism and function in hepatocellular carcinoma (HCC) is still unclear.
Xuesong Cen +9 more
doaj +1 more source
RBCK1 promotes hepatocellular carcinoma metastasis and growth by stabilizing RNF31
Cell Death Discovery, 2022 RNF31 (HOIP), RBCK1 (HOIL-1L), and SHARPIN are subunits of the linear ubiquitin chain assembly complex. Their function and specific molecular mechanisms in hepatocellular carcinoma (HCC) have not been reported previously.
Xijun Chen +5 more
doaj +1 more source
Molecular Therapy: Nucleic Acids, 2017 Long noncoding RNAs (lncRNAs) are a new class of regulatory noncoding RNAs. Emerging evidences indicate that lncRNAs play a critical role in the development of hepatocellular carcinoma (HCC).
Cheng-Rong Xie +10 more
doaj +1 more source
Yttrium-90 Selective Internal Radiation Therapy with Glass Microspheres for Hepatocellular Carcinoma: Current and Updated Literature Review. [PDF]
, 2016 Hepatocellular carcinoma is the most common primary liver cancer and it represents the majority of cancer-related deaths in the world. More than 70% of patients present at an advanced stage, beyond potentially curative options.
Alanis, Lourdes +3 more
core +1 more source
Increased nociceptin/orphanin FQ plasma levels in hepatocellular carcinoma [PDF]
, 2004 AIM: The heptadecapeptide nociceptin alias orphanin FQ is the endogenous agonist of opioid receptor-like1 receptor. It is involved in modulation of pain and cognition.
Dunkel, Kinga +7 more
core +1 more source
Frontiers in Oncology, 2021 Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death globally. Currently there is a lack of tumor-selective and efficacious therapies for hepatocellular carcinoma. β-Lapachone (ARQ761 in clinical form) selectively kill NADPH:
Wenxiu Zhao +15 more
doaj +1 more source