Results 21 to 30 of about 1,853,915 (311)

Clinical Practice Guidelines for Hepatocellular Carcinoma: The Japan Society of Hepatology 2021 version (5th JSH‐HCC Guidelines)

Hepatology Research, 2023
The fifth version of the Clinical Practice Guidelines for Hepatocellular Carcinoma was revised by the Japan Society of Hepatology, according to the methodology of evidence‐based medicine and partly to the Grading of Recommendations Assessment ...
K. Hasegawa, N. Takemura, T. Yamashita, T. Watadani, Masaki Kaibori, S. Kubo, M. Shimada, Hiroaki Nagano, E. Hatano, H. Aikata, H. Iijima, K. Ueshima, K. Ohkawa, Takuya Genda, K. Tsuchiya, T. Torimura, M. Ikeda, J. Furuse, M. Akahane, Satoshi Kobayashi, Hideyuki Sakurai, A. Takeda, Takamichi Murakami, U. Motosugi, Y. Matsuyama, M. Kudo, R. Tateishi   +26 more
semanticscholar   +1 more source

Tremelimumab plus Durvalumab in Unresectable Hepatocellular Carcinoma.

NEJM Evidence, 2022
Tremelimumab/Durvalumab for Hepatocellular CarcinomaThis trial examined overall survival (OS) with tremelimumab plus durvalumab, durvalumab alone, or sorafenib in untreated patients with hepatocellular cancer who were not candidates for locoregional ...
G. Abou-Alfa, G. Lau, M. Kudo, S. Chan, R. Kelley, J. Furuse, W. Sukeepaisarnjaroen, Yoon-Koo Kang, T. Van Dao, E. D. De Toni, L. Rimassa, V. Breder, Alexander Vasilyev, A. Heurgué, V. Tam, K. Mody, S. Thungappa, Y. Ostapenko, T. Yau, S. Azevedo, M. Varela, A. Cheng, S. Qin, P. Galle, Sajid Ali, M. Marcovitz, M. Makowsky, P. He, J. Kurland, A. Negro, B. Sangro   +30 more
semanticscholar   +1 more source

β-Lapachone Selectively Kills Hepatocellular Carcinoma Cells by Targeting NQO1 to Induce Extensive DNA Damage and PARP1 Hyperactivation

Frontiers in Oncology, 2021
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death globally. Currently there is a lack of tumor-selective and efficacious therapies for hepatocellular carcinoma. β-Lapachone (ARQ761 in clinical form) selectively kill NADPH:
Wenxiu Zhao, Wenxiu Zhao, Lingxiang Jiang, Ting Fang, Fei Fang, Yingchun Liu, Ye Zhao, Yuting You, Hao Zhou, Xiaolin Su, Jiangwei Wang, Sheng Liu, Yaomin Chen, Jun Wan, Jun Wan, Xiumei Huang   +15 more
doaj   +1 more source

RBCK1 promotes hepatocellular carcinoma metastasis and growth by stabilizing RNF31

Cell Death Discovery, 2022
RNF31 (HOIP), RBCK1 (HOIL-1L), and SHARPIN are subunits of the linear ubiquitin chain assembly complex. Their function and specific molecular mechanisms in hepatocellular carcinoma (HCC) have not been reported previously.
Xijun Chen, Qing Ye, Wenxiu Zhao, Xiaoqin Chi, Chengrong Xie, Xiaomin Wang   +5 more
doaj   +1 more source

Molecular pathogenesis and systemic therapies for hepatocellular carcinoma

Nature Cancer, 2022
Hepatocellular carcinoma (HCC) remains one of the most prevalent and deadliest cancers. The poor outcome associated with HCC is dramatically changing due to the advent of effective systemic therapies.
J. Llovet, R. Pinyol, R. Kelley, A. El-Khoueiry, H. Reeves, X. Wang, G. Gores, A. Villanueva   +7 more
semanticscholar   +1 more source

Yttrium-90 Selective Internal Radiation Therapy with Glass Microspheres for Hepatocellular Carcinoma: Current and Updated Literature Review. [PDF]

, 2016
Hepatocellular carcinoma is the most common primary liver cancer and it represents the majority of cancer-related deaths in the world. More than 70% of patients present at an advanced stage, beyond potentially curative options.
Alanis, Lourdes, Cho, Sung-Ki, Lee, Edward Wolfgang, Saab, Sammy   +3 more
core   +1 more source

Long Noncoding RNA HCAL Facilitates the Growth and Metastasis of Hepatocellular Carcinoma by Acting as a ceRNA of LAPTM4B

Molecular Therapy: Nucleic Acids, 2017
Long noncoding RNAs (lncRNAs) are a new class of regulatory noncoding RNAs. Emerging evidences indicate that lncRNAs play a critical role in the development of hepatocellular carcinoma (HCC).
Cheng-Rong Xie, Fei Wang, Sheng Zhang, Fu-Qiang Wang, Sen Zheng, Zhao Li, Jie Lv, He-Qiang Qi, Qin-Liang Fang, Xiao-Min Wang, Zhen-Yu Yin   +10 more
doaj   +1 more source

Hepatocellular carcinoma

Journal of British Surgery, 1998
Abstract Background Hepatocellular carcinoma is one of the world's most common malignancies. The aims of the present paper are to review data on (1) epidemiology and screening programmes for the early detection of the tumour and (2) advances in the diagnostic imaging and management.
Akriviadis, E. A., Llovet, J. M., Efremidis, S. C., Shouval, D., Canelo, R., Ringe, B., Meyers, W. C.   +6 more
openaire   +5 more sources

Histochemical and immunohistochemical analyses of primary carcinoma of the liver. [PDF]

, 1991
Hematoxylin and eosin (H-E) stained liver sections of 47 autopsy cases of hepatic malignancies were examined. There were 43 cases of hepatocellular carcinoma (subtypes of 30 trabecular, 7 solid, 5 pseudoglandular, and one scirrhous carcinoma), 3 of ...
Hayashi, Keiki, Sacho, Masanori, Setsu, Koujun   +2 more
core   +1 more source

Fibrolamellar hepatocellular carcinoma treated with atezolizumab and bevacizumab: two case reports

Journal of Medical Case Reports, 2021
Background Fibrolamellar hepatocellular carcinoma is a unique tumor of the liver that differs from the classical hepatocellular carcinoma in diagnosis, behavior, and possibly treatment.
Ali AL Zahrani, Ali Alfakeeh
doaj   +1 more source