Results 21 to 30 of about 566,938 (271)

ZNF561 antisense RNA 1 contributes to angiogenesis in hepatocellular carcinoma through upregulation of platelet-derived growth Factor-D

Chinese Journal of Physiology, 2022
Hepatocellular carcinoma is a common malignant tumor with high recurrence rate. Long non-coding RNA (lncRNA) ZNF561 antisense RNA 1 (ZNF561-AS1) functions as an oncogenic lncRNA to promote the tumorigenesis of colorectal cancer. The role of ZNF561-AS1 in
Jihu Zheng, Zijian Guo, Zhanchao Wen, Huikang Chen   +3 more
doaj   +1 more source

The role of Micro-RNAs in Hepatocellular Carcinoma: From Molecular Biology to Treatment [PDF]

, 2014
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the third leading cause of cancer deaths. microRNAs (miRNAs) are evolutionary conserved small non-coding RNA that negatively regulate gene expression and protein translation ...
Bianconi Maristella, Cascinu Stefano, D'Anzeo Marco, Del Prete Michela, Faloppi Luca, Giampieri Riccardo, SCARTOZZI, MARIO, Silvestris Nicola   +7 more
core   +1 more source

Elevated N‐methyltransferase expression induced by hepatic stellate cells contributes to the metastasis of hepatocellular carcinoma via regulation of the CD44v3 isoform

Molecular Oncology, 2019
The cross‐talk between hepatic stellate cells (HSCs) and hepatic carcinoma cells contributes to hepatocellular carcinoma (HCC) progression, but the underlying mechanism is largely unknown.
Jie Li, Song You, Sheng Zhang, Qing Hu, Fuqiang Wang, Xiaoqin Chi, Wenxiu Zhao, Chengrong Xie, Changmao Zhang, Yaqi Yu, Jianmin Liu, Yue Zhao, Pingguo Liu, Yi Zhang, Xujin Wei, Qiu Li, Xiaomin Wang, Zhenyu Yin   +17 more
doaj   +1 more source

A Surgical Perspective on Targeted Therapy of Hepatocellular Carcinoma. [PDF]

, 2015
Hepatocellular carcinoma (HCC), the second leading cause of cancer deaths worldwide, is difficult to treat and highly lethal. Since HCC is predominantly diagnosed in patients with cirrhosis, treatment planning must consider both the severity of liver ...
Busuttil, Ronald W, Faltermeier, Claire, Zarrinpar, Ali   +2 more
core   +2 more sources

MLN2238 exerts its anti-tumor effects via regulating ROS/JNK/mitochondrial signaling pathways in intrahepatic cholangiocarcinoma

Frontiers in Pharmacology, 2022
Background: Intrahepatic Cholangiocarcinoma (iCCA) is a highly malignant tumor with limited treatment options that contributes largely to cancer-related deaths worldwide.
Hao Xu, Hao Xu, Hao Xu, Hao Xu, Hao Xu, Hao Xu, Guangyu Xu, Guangyu Xu, Guangyu Xu, Guangyu Xu, Guangyu Xu, Guangyu Xu, Qianhui Xu, Qianhui Xu, Qianhui Xu, Qianhui Xu, Qianhui Xu, Qianhui Xu, Chang Xu, Chang Xu, Chang Xu, Chang Xu, Chang Xu, Chang Xu, Xiaohu Zhou, Yang Bai, Yang Bai, Yang Bai, Yang Bai, Yang Bai, Yang Bai, Lu Yin, Yuan Ding, Yuan Ding, Yuan Ding, Yuan Ding, Yuan Ding, Yuan Ding, Weilin Wang, Weilin Wang, Weilin Wang, Weilin Wang, Weilin Wang, Weilin Wang   +43 more
doaj   +1 more source

hsa_circ_0006916 promotes hepatocellular carcinoma progression by activating the miR-337-3p/STAT3 axis

Cellular & Molecular Biology Letters, 2020
Background Circular RNAs (circRNAs) are thought to be involved in the development of various malignancies. The expression and function of hsa_circ_0006916, a newly identified circRNA, in hepatocellular carcinoma remain unclear.
Xiao-Yong Zhou, Hui Yang, Yang-Qiu Bai, Xiu-Ling Li, Shuang-Yin Han, Bing-Xi Zhou   +5 more
doaj   +1 more source

Basic and Clinical Research Progress of Immunotherapy for Hepatocellular Carcinoma

Zhongliu Fangzhi Yanjiu, 2023
Primary liver cancer, especially hepatocellular carcinoma, poses a serious threat to the life and health of the Chinese people. Given the insidious onset of liver cancer, less than 30% of hepatocellular carcinoma patients are considered for radical ...
ZHANG Zechuan, SUN Beicheng
doaj   +1 more source

Liver resection or combined chemoembolization and radiofrequency ablation improve survival in patients with hepatocellular carcinoma [PDF]

, 2007
Background/ Aims: To evaluate the long-term outcome of surgical and non-surgical local treatments of patients with hepatocellular carcinoma (HCC). Methods: We stratified a cohort of 278 HCC patients using six independent predictors of survival according ...
Angelika Schrader, Bloomston M, Bosch FX, Burkhard Göke, Castells A, Christian Graeb, Christoph Jüngst, Curley SA, Dieter Jüngst, Florian Löhe, Franco D, Goldberg SN, Gundula Straub, Horst-Günter Rau, Karl-Walter Jauch, Kotoh K, Livraghi T, Livraghi T, Livraghi T, Maximilian Reiser, Qian J, Ralf-Thorsten Hoffmann, Rolf Schauer, Rossi S, Rossi S, Ryder SD, Sasaki Y, Selin Dogan, Takenaka K, Thomas Helmberger, Tobias Jakobs, Tobias Waggershauser, Wolfgang H. Caselmann   +32 more
core   +1 more source

CDK5-mediated phosphorylation and stabilization of TPX2 promotes hepatocellular tumorigenesis

Journal of Experimental & Clinical Cancer Research, 2019
Background CDK5, an atypical member of the CDK family, play a significant role in the tumorigenesis of multiple organ, but CDK5 and its substrates in genesis and development of HCC is still unclear.
Fuqiang Wang, Wenxing Zhao, Yuehong Gao, Jiechao Zhou, Huifang Li, Guanyun Zhang, Dong Guo, Chengrong Xie, Jie Li, Zhenyu Yin, Jie Zhang   +10 more
doaj   +1 more source

Spatially resolved visualization of reprogrammed metabolism in hepatocellular carcinoma by mass spectrometry imaging

Cancer Cell International, 2023
Background Metabolic reprogramming refers to tumor-associated metabolic alterations during tumorigenesis and has been regarded as one of the most important features of cancer.
Bangzhen Ma, Yang Zhang, Jiwei Ma, Xinguo Chen, Chenglong Sun, Chengkun Qin   +5 more
doaj   +1 more source