Results 141 to 150 of about 106,450 (263)

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

Pediatric Blood &Cancer, Volume 73, Issue 5, May 2026.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy, Elizabeth L. Seashore, W. Susan Cheng, Shondra Clay, Jessica A. Casas, Jennifer H. Foster   +5 more
wiley   +1 more source

Multiple Oral and Eyelid Nodules in a Pediatric Patient

Oral Diseases, EarlyView.
Caique Mariano Pedroso, Paulo Victor Mendes Penafort, Patrícia Vitor de Souza, Fernanda M. Pascon, Regina Maria Punppin‐Rontani, Beatriz Frolini Paulo Cherve, Rachel Marinho Robim, Regina Maria Holanda de Mendonça, Marcio Ajudarte Lopes, Pablo Agustin Vargas, Alan Roger Santos‐Silva   +10 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, Volume 16, Issue 5, Page 944-965, May 2026.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Differentiation of Fat‐Poor Renal Angiomyolipoma From Clear Cell Renal Cell Carcinoma: Diagnostic Performance of a Novel Type of Color Contrast Enhanced Ultrasound

Cancer Medicine, Volume 15, Issue 5, May 2026.
Our study confirms CPI can distinguish AML.wovf from ccRCC, potentially helping patients with AML.wovf avoid unnecessary surgery. These findings expand CPI's clinical utility, providing a promising tool for diagnosing renal tumors. ABSTRACT Background The similar imaging characteristics of renal angiomyolipoma without visible fat (RAML.wvf) and clear ...
Yiman Du, Xuyang Wang, Bo Jiang, Luda Song, Yukun Luo, Qiuyang Li   +5 more
wiley   +1 more source

Development of a Machine Learning‐Based Predictive Model for Central Lymph Node Metastasis in Papillary Thyroid Microcarcinoma

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background Central lymph nodes metastasis (CLNM) is common in papillary thyroid. Microcarcinoma (PTMC). Whilst prophylactic central lymph node dissection (CLND) can prevent further CLNM, it remains controversial. An accurate model to predict CLNM is therefore necessary for patients with PTMC.
Tao Li, Thomas O. Butler, Yaopeng Hu, Sha Li   +3 more
wiley   +1 more source

Diagnostic Utility of a Cost‐Effective Four‐Gene Next Generation Sequencing Panel for Predicting Papillary Thyroid Carcinoma in Indeterminate Thyroid Cytology: A Multicenter Study in China

Cancer Medicine, Volume 15, Issue 5, May 2026.
This multicenter study of 827 thyroid nodules demonstrates that a targeted NGS 4‐gene panel (BRAF^V600E, TERT promoter, RET fusions, NTRK3 fusion) achieves high diagnostic accuracy (88.2%) and PPV (99.62%) for cytologically indeterminate Bethesda III–V nodules, offering a cost‐effective first‐line molecular test in China. ABSTRACT Molecular testing has
Qiong Jiao, Ling Wu, Bing Wei, Qing Li, Xuling Su, Keyang Sun, Xiaoyue Zhang, Yanli Luo, Zhiyan Liu   +8 more
wiley   +1 more source

What Is Your Diagnosis? Submandibular Mass in a Dog

Veterinary Clinical Pathology, EarlyView.
Whitney K. Chandler, Barbara E. Powers, Devorah M. Stowe, Nancy B. Collicutt   +3 more
wiley   +1 more source

Systematic Management of a Critical CYP3A4 Interaction Between Cabozantinib and Carbamazepine: A Case Report of a Clinically Relevant Pharmacokinetic Interaction

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT This was the case of a 62‐year‐old patient treated with cabozantinib and nivolumab for metastatic clear cell renal cell carcinoma, in whom a clinically significant pharmacokinetic interaction with carbamazepine was observed. Carbamazepine, a potent inducer of CYP3A4, caused a major decrease in systemic exposure to cabozantinib, as confirmed by
Pierre Nizet, Jean‐François Huon, Caroline Viala, Siméon Robin, Wala Ammor   +4 more
wiley   +1 more source

What Is Your Diagnosis? Superficial Cervical Lymph Node Cytology

Veterinary Clinical Pathology, EarlyView.
Vinicius N. Hirata, Rúbia S. da Silva, Francisca B. Lang, Augusto de Oliveira, Cinthia M. de Andrade   +4 more
wiley   +1 more source

Papillary Thyroid Carcinoma Originating in a Male With Thyroglossal Duct Cyst: Case Presentation and Literature Review

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Papillary carcinoma arising in a thyroglossal duct cyst is rare and often indistinguishable from benign disease. We report a male patient with progressive cyst changes leading to diagnosis and successful Sistrunk‐based management, highlighting the need for close, appropriate imaging and individualized treatment in midline neck masses.
Nasim Abukaresh, Hossam Salameh, Tala Dweik, Anan Dawadi, Haya Taha, Sohaib Salahat, Ahmed Aljodi   +6 more
wiley   +1 more source