Results 81 to 90 of about 16,548 (197)
This dataset is about the differentially expressed exosomal microRNA between MCPyV-negative and -positive MCC cell lines.Abstract: MicroRNAs (miRNAs) are small non-coding RNAs responsible for post-transcriptional regulation of gene expression through ...
Konstantinell, Aelita Gloria Virginia
core +1 more source
Through Jimmy Buffett’s unfortunate battle with lymphoma originating from Merkel cell carcinoma and subsequent media coverage of his death, public interest in skin cancer, Merkel cell carcinoma, and the health effects of sunlight exposure increased, as ...
Macy Haight +4 more
doaj +1 more source
ABSTRACT Background There is a lack of knowledge in full‐body skin examinations (FBSEs) in the context of pathogenic or likely pathogenic variants (PV/LPV) in skin cancer predisposition genes (CPGs). This study assessed the association between carrier status of PV/LPV in skin CPGs and FBSEs and described the patterns of family letter receipt, familial ...
Jincong Q. Freeman +4 more
wiley +1 more source
Merkel cell polyomavirus strains in patients with merkel cell carcinoma [PDF]
International audienceWe investigated whether Merkel cell carcinoma (MCC) patients in France carry Merkel cell polyomavirus (MCPyV) and then identified strain variations. All frozen MCC specimens and 45% of formalin-fixed and paraffin-embedded specimens,
Durlach, Anne +21 more
core +1 more source
Merkel cell distribution in the human eyelid
Although Merkel cell carcinoma of the eye lid is reported frequently in the literature, only limited information exists about the distribution of Merkel cells in this tissue.
C.A. May, I. Osterland
doaj +1 more source
Lambert-Eaton myasthenic syndrome (LEMS) is a rare, autoimmune or paraneoplastic condition characterized by muscle weakness and fatigability. In cancer therapy, immune checkpoint inhibitors (ICI) sensitize the immune system for tumor antigens.
Maike F. Dohrn +6 more
doaj +1 more source
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
Immunotherapy in Merkel cell carcinoma: role of Avelumab
Amruth R Palla, Donald Doll Department of Internal Medicine, Division of Hematology and Oncology, Ellis Fischel Cancer Center, University of Missouri, Columbia, MO, USA Abstract: Merkel cell carcinoma (MCC), a rare skin cancer, is associated with ...
Palla AR, Doll D
core
Immunotherapy‐Related Cutaneous Toxicities in Melanoma: A Dermoscopic Perspective
Dermoscopy serves as a valuable tool in the everyday dermatological and oncological practice for melanoma patients, allowing for the prompt identification of immune‐related cutaneous toxicities and guiding clinicians toward appropriate therapeutic decisions.
Grażyna Kamińska‐Winciorek +3 more
wiley +1 more source
Merkel Cell Carcinoma in a Child
Merkel cell carcinoma, a rare tumor of the skin with aggressive behavior, is usually fatal when advanced disease is present. Merkel cell carcinoma occurs mostly in white race between 60 and 80 years of age, however, it can occur in any races and ages. It
Toy, Hatice +5 more
core +1 more source

