Results 181 to 190 of about 136,755 (290)
ABSTRACT Introduction BRCA2 alterations and high tumor mutational burden (TMB‐H) are responsible for prostate cancer; however, their co‐occurrence is uncommon, and evidence for PARP inhibition in the castration‐sensitive setting remains limited. We describe a case of metastatic castration‐resistant prostate cancer (CRPC) harboring both biomarkers ...
Kotaro Yokota +6 more
wiley +1 more source
Ovarian Neuroendocrine Neoplasms: Challenges and Future Perspectives. [PDF]
Di Vito V +12 more
europepmc +1 more source
Non‐Functional Paraganglioma of the Urinary Bladder: A Rare Cause of Bladder Tumor
ABSTRACT Introduction Paragangliomas of the urinary bladder (PUBs) are rare neuroendocrine tumors, representing less than 0.06% of all bladder neoplasms. While most are functional and associated with catecholamine excess, approximately 15% are non‐functional, often presenting asymptomatically and discovered incidentally.
Matt Wainstein +4 more
wiley +1 more source
Glucose-transporter 1 (GLUT1) as a prognostic biomarker: evidence from 14,966 human tumors across 134 cancer types. [PDF]
Büyücek S +27 more
europepmc +1 more source
Membrane proeteins as markers for normal and neoplastic endocrine cells [PDF]
Gratzl, Manfred +2 more
core
Human Cyclophilins—An Emerging Class of Drug Targets
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
Primary large cell neuroendocrine carcinoma of the breast diagnosed using dynamic contrast-enhanced magnetic resonance imaging and diffusion-weighted imaging: A case report. [PDF]
Kim B, Choi S, Kim KM, Choi EJ.
europepmc +1 more source
Local Anesthetics in Cancer: Mechanisms and Translational Perspectives
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang +4 more
wiley +1 more source

