Results 1 to 10 of about 616,145 (212)

Targeted therapy of non-small-cell lung carcinoma [PDF]

open access: yesTherapeutic Advances in Respiratory Disease, 2012
The rapid expansion of novel technologies in cancer research over the past several years has led to a dramatically improved understanding of the molecular biology of lung cancer. As a consequence, novel targeted therapies are rapidly being developed.
Divya Tiwari   +2 more
doaj   +3 more sources

Cetuximab and biomarkers in non-small-cell lung carcinoma

open access: yesBiologics: Targets & Therapy, 2012
Nitin Patil, Mohammed Abba, Heike AllgayerDepartment of Experimental Surgery, Medical Faculty Mannheim, University of Heidelberg and Molecular Oncology of Solid Tumors Unit, German Cancer Research Center (DKFZ), Heidelberg, GermanyAbstract: Cancer ...
Patil N, Abba M, Allgayer H
doaj   +4 more sources

the Immunohistochemical Study of Stathmin-1 as A Prognostic factor In Non-small cell lung carcinoma

open access: yesمجلة كلية الطب, 2023
Background Stathmin1 (also known as metablastin) is a major microtubule-depolymerizing protein that involved in cell cycle progression and cell motility.
Nadhema Bahaa Hussein Wetwet   +3 more
doaj   +1 more source

Lung: Non-small cell carcinoma [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Non-small cell carcinomas are divided into three main categories according to the predominant morphology of the tumour cells as determined by light microscopy. Although it is possible to distinguish different histological sub-groups in this way, or by using gene expression profiling, treatment is currently decided on the basis of tumour staging, age ...
J Heighway, DC Betticher
openaire   +1 more source

Lung Cancer: A Literature Review

open access: yesJurnal Respirasi, 2023
Lung cancer is a cancer whose onset starts in the lungs where there is an abnormal cell growth that is very fast and uncontrolled. The abnormal cell growth is triggered by deoxyribonucleic acid (DNA) damage, including deletions in the DNA section ...
Yan Efrata Sembiring   +8 more
doaj   +1 more source

Dramatic response to pembrolizumab with chemotherapy followed by salvage surgery in a lung cancer patient

open access: yesThoracic Cancer, 2021
Immune checkpoint inhibitors with chemotherapy have been shown to exhibit remarkable efficacy for advanced non‐small‐cell lung carcinoma and are under investigation as an induction therapy.
Shunichi Saito   +6 more
doaj   +1 more source

Partial Response in an RRx-001-Primed Patient with Refractory Small-Cell Lung Cancer after a Third Introduction of Platinum Doublets. [PDF]

open access: yes, 2016
Small-cell lung cancer (SCLC), initially exquisitely sensitive to first-line cisplatin/etoposide, invariably relapses and acquires a multidrug chemoresistant phenotype that generally renders retreatment with first-line therapy both futile and ...
Brzezniak, Christina   +7 more
core   +6 more sources

A rare case of pulmonary endobronchial spindle cell carcinoma with liver metastasis along with concurrent cutaneous neurofibroma

open access: yesThe Journal of Association of Chest Physicians, 2023
Spindle cell carcinoma is one of the histological variants of pulmonary sarcomatoid carcinoma. It is a rare, poorly differentiated, highly malignant, and rapidly growing non-small cell carcinoma of the lung.
Pratap Upadhya   +3 more
doaj   +1 more source

Leser‐Trélat syndrome secondary to non‐small‐cell lung carcinoma

open access: yesClinical Case Reports, 2022
The syndrome of Leser‐Trélat (LT) is a rare paraneoplastic syndrome. However, patients presenting with the sign of Leser‐Trélat should be considered to harbor an occult malignancy or a progressive tumor disease until “proven” otherwise.
Rim Khemakhem   +4 more
doaj   +1 more source

Pulmonary pleomorphic carcinoma presenting as undifferentiated non-small cell carcinoma with giant cells: A case report and review of literature

open access: yesRespiratory Medicine Case Reports, 2020
Pulmonary pleomorphic carcinoma (PPC) is a poorly differentiated non-small cell lung carcinoma, including squamous cell carcinoma, adenocarcinoma, or undifferentiated non-small cell lung carcinoma with at least 10% spindle and/or giant cells.
Jae-Han Jeong   +3 more
doaj   +1 more source

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