Results 31 to 40 of about 843,078 (353)

Non-small cell lung carcinoma metastasis to the anus [PDF]

BMJ Case Reports, 2016
A 70-year-old man presenting with a lung mass was investigated and treated with pneumonectomy for adenocarcinoma of the lung. He re-presented 3 months later with a large perianal abscess and mass. Subsequent investigations and biopsies showed disseminated metastases from the lung primary.
Ramya Gowri, Dhandapani, Chinedum, Anosike, Akash, Ganguly   +2 more
openaire   +2 more sources

Partial Response in an RRx-001-Primed Patient with Refractory Small-Cell Lung Cancer after a Third Introduction of Platinum Doublets. [PDF]

, 2016
Small-cell lung cancer (SCLC), initially exquisitely sensitive to first-line cisplatin/etoposide, invariably relapses and acquires a multidrug chemoresistant phenotype that generally renders retreatment with first-line therapy both futile and ...
Brzezniak, Christina, Cabrales, Pedro, Caroen, Scott, Carter, Corey A, Degesys, Aiste, Oronsky, Bryan, Reid, Tony R, Scicinski, Jan   +7 more
core   +3 more sources

Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer. [PDF]

PLoS ONE, 2011
Squamous cell lung carcinomas account for approximately 25% of new lung carcinoma cases and 40,000 deaths per year in the United States. Although there are multiple genomically targeted therapies for lung adenocarcinoma, none has yet been reported in ...
Amit Dutt, Alex H Ramos, Peter S Hammerman, Craig Mermel, Jeonghee Cho, Tanaz Sharifnia, Ajit Chande, Kumiko Elisa Tanaka, Nicolas Stransky, Heidi Greulich, Nathanael S Gray, Matthew Meyerson   +11 more
doaj   +1 more source

Overexpression of the non-coding SOX2OT variants 4 and 7 in lung tumors suggests an oncogenic role in lung cancer [PDF]

, 2016
Despite the advances in cancer therapy, lung cancer still remains the most leading cause of cancer death worldwide. The long non-coding RNAs (lncRNAs) are recently introduced as novel regulators of human cancers. SOX2 overlapping transcript (SOX2OT) is a
Ghanei, M., Mowla, S.J., Saghaeian Jazi, M., Samaei, N.M., Shadmehr, M.B.   +4 more
core   +1 more source

Influence of ABO blood group on susceptibility to different pathological types of lung cancer: a retrospective study

World Journal of Surgical Oncology, 2022
Purpose Current research has shown a link between ABO blood group and many diseases. The purpose of this study aimed to investigate the influence of the ABO blood group on the risk of developing different pathological types of lung cancer.
Haotian Yang, Xianjun Zeng, Yu Zhang, Weilai Tong, Geliang Yao, Chunyu Lan, Jiaming Liu, Zhili Liu, Nanshan Zhong   +8 more
doaj   +1 more source

Pinpointing pin1 in non-small cell lung carcinoma [PDF]

Cancer Biology & Therapy, 2010
Factors that promote tumorigenesis encompass a wide array of proteins that include transcription factors, signal transduction molecules, negative regulators of tumor suppressors, transmembrane receptors and enzymes involved in a variety of processes. Identifying these factors remains one of the most pertinent issues in cancer research, as they can be ...
Joseph, Catanzaro, Wei-Xing, Zong
openaire   +2 more sources

Five-Year Survival and Correlates Among Patients With Advanced Melanoma, Renal Cell Carcinoma, or Non–Small Cell Lung Cancer Treated With Nivolumab

JAMA Oncology, 2019
This secondary analysis of the phase 1 CA209-003 clinical trial assesses the 5-year survival and other related factors among patients with advanced melanoma, renal cell carcinoma, or non–small cell lung cancer receiving nivolumab.
S. Topalian, F. Hodi, J. Brahmer, S. Gettinger, David C. Smith, D. McDermott, J. Powderly, J. Sosman, J. Sosman, M. Atkins, M. Atkins, P. Leming, D. Spigel, S. Antonia, A. Drilon, J. Wolchok, R. Carvajal, R. Carvajal, M. McHenry, F. Hosein, C. Harbison, J. Grosso, M. Sznol   +22 more
semanticscholar   +1 more source

Spatial Density and Distribution of Tumor-Associated Macrophages Predict Survival in Non–Small Cell Lung Carcinoma

Cancer Research, 2020
This study underlines the significance of the density, spatial distribution, and gene expression of TAM phenotypes as prognostic factors for overall survival in lung cancer.
Xiang Zheng, A. Weigert, S. Reu, S. Guenther, S. Mansouri, B. Bassaly, S. Gattenlöhner, F. Grimminger, S. Savai Pullamsetti, W. Seeger, H. Winter, R. Savai   +11 more
semanticscholar   +1 more source

Current WHO guidelines and the critical role of immunohistochemical markers in the subclassification of non-small cell lung carcinoma (NSCLC): Moving from targeted therapy to immunotherapy.

Seminars in Cancer Biology, 2017
Recent large scale genomic studies from the Clinical Lung Cancer Genome Project have identified different driver gene mutations in the subtypes of non-small cell lung carcinoma (NSCLC).
Lais Osmani, F. Askin, E. Gabrielson, Q. K. Li   +3 more
semanticscholar   +1 more source

N6-methyladenosine-modified circIGF2BP3 inhibits CD8+ T-cell responses to facilitate tumor immune evasion by promoting the deubiquitination of PD-L1 in non-small cell lung cancer

Molecular Cancer, 2021
Background An in-depth understanding of immune evasion mechanisms in tumors is crucial to overcome resistance and enable innovative advances in immunotherapy. Circular RNAs (circRNAs) have been implicated in cancer progression.
Zhenchuan Liu, Tingting Wang, Y. She, Kaiqin Wu, Shaorui Gu, Lei Li, C. Dong, Chang Chen, Yongxin Zhou   +8 more
semanticscholar   +1 more source