Results 41 to 50 of about 19,522,173 (311)

Concurrent chemo-radiotherapy for locally advanced non-small cell lung cancer using intensity-modulated radiotherapy technique [PDF]

Al-Azhar International Medical Journal, 2020
Background: major progress in the management of non-small cell lung cancer emerged in the last years. Survival rate markedly improved in locally advanced non-small cell lung cancer with the use of concurrent chemoradiotherapy treatment.
Ahmed Al-Agamawi, Khaled Halima, Wael El-Sheshtawy, Mohammed Tarrad   +3 more
doaj   +1 more source

Mapping of Multiple DNA Gains and Losses in Primary Small Cell Lung Carcinomas by Comparative Genomic Hybridization [PDF]

, 1994
Comparative genomic hybridization was applied for a comprehensive screening of under- and overrepresentation of genetic material in 13 autoptic small cell lung cancer specimens.
Speicher, Michael R., Cremer, Thomas, Petersen, Iver, Ried, Thomas, Manoir, Stanislas du, Schröck, Evelin, Holtgreve-Grez, Heidi   +6 more
core   +1 more source

Joint co-clustering: co-clustering of genomic and clinical bioimaging data [PDF]

, 2007
For better understanding the genetic mechanisms underlying clinical observations, and better defining a group of potential candidates for protein-family-inhibiting therapy, it is interesting to determine the correlations between genomic, clinical data ...
Benini, L., De Micheli, Giovanni, Enrico Macii, Benini, Luca, G. De Micheli, S. Yoon, Yoon, S., E. Macii, Sungroh Yoon, DE MICHELI G, Elisa Ficarra, Giovanni De Micheli, Ficarra, Elisa, YOON S, E. Ficarra, Macii, Enrico, Yoon, Sungroh, De Micheli, G., Luca Benini, BENINI L   +19 more
core   +1 more source

CMTM6: a potential biomarker in non-small cell lung carcinoma

Polish Journal of Pathology
Lung cancer is the most common cause of cancer-related deaths worldwide. With the advent of immunotherapy, programmed cell death-1 and programmed death ligand 1 (PD-L1) inhibitors have gained clinical importance, driving research into their regulatory ...
Seda Tas Ayçiçek, Sıddıka Fındık
doaj   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

MMP-10 is overexpressed, proteolytically active and a potential target for therapeutic intervention in human lung carcinomas [PDF]

, 2004
NoMatrix metalloproteinase (MMP)-mediated degradation of the extracellular matrix is a major factor for tumor development and expansion. This study analysed MMP-10 protein expression and activity in human lung tumors of various grade, stage, and type to ...
Tijani, S., Jason H. Gill, Martin, Sandie W., Alan J. Mearns, Alan Anthoney, Mearns, A.J., Kirwan, I.G, Anikin, V.A., Anikin, V.A, Gill, J.H, Tijani, S, Loadman, Paul, Anthoney, A, Jill M. Seargent, Sandie W. Martin, Mearns, Alan J., Kirwan, Ian G., Seargent, Jill M., Anthoney, Alan, Loadman, P.M, Seargent, J.M, Mearns, A.J, Anikin, Vladimir A., Ian G. Kirwan, Tijani, Sidiq, Bibby, M.C, Martin, S.W, Sidiq Tijani, Bibby, Michael C., Loadman, Paul M., Gill, Jason H., Michael C. Bibby, Paul M. Loadman, Vladimir A. Anikin   +33 more
core   +1 more source

Study of PD-L1 Expression in Tumours Based on Site and Histology of Tumour – The Experience of a Tertiary Referral Laboratory

Asian Pacific Journal of Cancer Biology, 2023
Background: PD-L1 IHC test is used as a predictive biomarker using FDA-approved assays to select patients likely to benefit from immunotherapy in several advanced-stage tumors. We aim to present our data regarding the prevalence and expression pattern of
Vinita Pant, Munmun Harlalka
doaj   +1 more source

Ewing Sarcoma in Infants and Children Under 2 Years of Age: A French Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ewing sarcoma, the second most common primary bone cancer in children, requires intensive treatment that may lead to significant long‐term sequelae, particularly in infants. We retrospectively analyzed data from 1621 French patients treated between 1988 and 2015 within the EW88/93/97 or EE99 trials, focusing on 17 infants diagnosed before 24 ...
Elodie Verdier, Nathalie Cozic, Marie‐Dominique Tabone, Gaelle Pierron, Perrine Marec‐Berard, Sarah Winter, Gabriel Revon‐Rivière, Cyril Lervat, Dominique Plantaz, Marie‐Pierre Castex, Gregory Guimard, Estelle Thebaud, Stephanie Proust, Laure Saumet, Natacha Entz‐Werle, Sophie Taque, Cécile Vérité, Marta Jimenez, Nathalie Gaspar   +18 more
wiley   +1 more source

Erlotinib in patients with previously irradiated, recurrent brain metastases from non-small cell lung cancer: Two case reports [PDF]

, 2008
Background: With the current improvements in primary lung care, the long-term control of brain metastases becomes a clinical challenge. No established therapeutic approaches exist for cranial relapse after response to previous radiotherapy and systemic ...
Pawel, Joachim, Wagner, Horst, Poellinger, Barbara, Duell, Thomas   +3 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source