Results 41 to 50 of about 843,078 (353)

Exploiting metabolic vulnerabilities of Non Small Cell Lung Carcinoma.

Seminars in Cell and Developmental Biology, 2020
Lung cancer is the main cause of cancer death worldwide. Non-Small Cell Lung Carcinoma (NSCLC) is the most common subtype of lung cancer, and the prognosis of NSCLC patients in advanced stages is still very poor.
B. Majem, E. Nadal, C. Muñoz-Pinedo
semanticscholar   +1 more source

EGFR mutation testing in non-small cell lung cancer (NSCLC)

Journal of Infection and Public Health, 2012
Summary: Lung carcinoma is subdivided into small cell carcinoma and non-small cell carcinoma (NSCLC). NSCLC is heterogeneous group of carcinomas and accounts for 70–80% of lung cancer. NSCLC is further divided into adenocarcinoma, squamous cell carcinoma,
Fouad Al Dayel
doaj   +1 more source

Hypoxia increases membrane metallo-endopeptidase expression in a novel lung cancer ex vivo model - role of tumor stroma cells [PDF]

, 2014
Background: Hypoxia-induced genes are potential targets in cancer therapy. Responses to hypoxia have been extensively studied in vitro, however, they may differ in vivo due to the specific tumor microenvironment.
Gallé, B. (Birgit), Guelly, C. (Christian), Hofmann, N.A. (Nicole), Hrzenjak, A. (Andelko), Leithner, K. (Katharina), Lindenmann, J. (Jörg), Olschewski, A. (Andrea), Olschewski, H. (Horst), Philipsen, J.N.J. (Sjaak), Popper, H.H. (Helmut), Quehenberger, F. (Franz), Smolle-Jüttner, F.-M. (Freyja-Maria), Stacher, E. (Elvira), Stiegler, P. (Philipp), Wohlkoenig, C. (Christoph)   +14 more
core   +1 more source

Identification of distinct N-glycosylation patterns on extracellular vesicles from small-cell and non–small-cell lung cancer cells

Journal of Biological Chemistry, 2022
Asparagine-linked glycosylation (N-glycosylation) of proteins in the cancer secretome has been gaining increasing attention as a potential biomarker for cancer detection and diagnosis.
Kiyotaka Kondo, Yoichiro Harada, M. Nakano, Takehiro Suzuki, T. Fukushige, K. Hanzawa, H. Yagi, K. Takagi, K. Mizuno, Y. Miyamoto, Naoyuki Taniguchi, Koichi Kato, T. Kanekura, N. Dohmae, K. Machida, I. Maruyama, H. Inoue   +16 more
semanticscholar   +1 more source

"Person in the barrel" syndrome: Unusual heralding presentation of squamous cell carcinoma of the lung

Annals of Indian Academy of Neurology, 2016
Paraneoplastic neurological syndromes (PNS) are rare and relatively unusual in day to day clinical practice. Occasionally, PNS may be the heralding manifestation of the malignancy.
Rajesh Verma, Rakesh Lalla, Tushar B Patil, Suresh Babu   +3 more
doaj   +1 more source

Concomitant occurrence of EGFR (epidermal growth factor receptor) and KRAS (V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog) mutations in an ALK (anaplastic lymphoma kinase)-positive lung adenocarcinoma patient with acquired resistance to crizotinib: a case report [PDF]

, 2013
BACKGROUND: Anaplastic lymphoma kinase-positive non-small cell lung carcinoma patients are generally highly responsive to the dual anaplastic lymphoma kinase and MET tyrosine kinase inhibitor crizotinib.
Birgit G Skov, Charlotte K Rask, Edyta M Urbanska, Eric Santoni-Rugiu, Henrik H Rossing, Jens Sørensen, Junia C Costa, Linea C Melchior, Morten Grauslund   +8 more
core   +1 more source

Tumor-derived exosomal miR-3157-3p promotes angiogenesis, vascular permeability and metastasis by targeting TIMP/KLF2 in non-small cell lung cancer

Cell Death and Disease, 2021
Metastasis is the main cause of death in patients with advanced lung cancer. The exosomes released by cancer cells create tumor microenvironment, and then accelerate tumor metastasis.
Zijian Ma, Ke Wei, Fengming Yang, Zizhang Guo, Chunfeng Pan, Yaozhou He, Jun Wang, Zhihua Li, Liang Chen, Yijiang Chen, Yang Xia   +10 more
semanticscholar   +1 more source

Changing trends in incidence of lung cancer by histological type in Montenegro [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2014
Introduction. Lung cancer is one of the most common malignant neoplasms, as well as the most common cause of death cancer. Most lung cancers are squamous cell carcinomas, small cell carcinomas or adenocarcinomas. Objective.
Medenica Milić, Medenica Miraš, Bojović Olivera, Soldatović Ivan, Durutović Ivana   +4 more
doaj   +1 more source

A Case Report of Small Cell Lung Carcinoma in a Patient with Progressive Diffuse Sclerosis

Journal of Mazandaran University of Medical Sciences, 2022
Connective tissue diseases, including scleroderma, may be associated with an increased risk of lung cancer. The most common type of lung cancer associated with systemic sclerosis is adenocarcinoma or bronchoalveolar carcinoma, and small cell carcinoma is
Hojatolah Ghorbani, Maryam Mobini, Ehsan Zaboli, Laleh Vahedi Larijani, Hadi Majidi   +4 more
doaj  

Genetic variant of miR-4293 rs12220909 is associated with susceptibility to non-small cell lung cancer in a Chinese Han population. [PDF]

PLoS ONE, 2017
Non-small cell lung cancer is one of the most common cancers and the leading cause of cancer death worldwide. Genetic variants in regulatory regions of some miRNAs might be involved in non-small cell lung cancer susceptibility and survival. rs12220909 (G/
Lixia Fan, Linqi Chen, Xiaoling Ni, Shicheng Guo, Yinghui Zhou, Chenji Wang, Yabiao Zheng, Fangyuan Shen, Vijay Kumar Kolluri, Merlin Muktiali, Zhenhong Zhao, Junjie Wu, Dunmei Zhao, Zhenglei He, Xulong Feng, Ziyu Yuan, Juan Zhang, Li Jin, Jiucun Wang, Minghua Wang   +19 more
doaj   +1 more source