Results 51 to 60 of about 843,078 (353)

Histological transformation of adenocarcinoma to small cell carcinoma lung as a rare mechanism of resistance to epidermal growth factor receptor-tyrosine kinase inhibitors: Report of a case with review of literature

Lung India, 2018
A subset of non-small cell lung carcinoma (NSCC) harbor active mutations of epidermal growth factor receptor (EGFR). In these, EGFR tyrosine kinase inhibitors (EGFR-TKIs) are recommended as the first-line treatment.
Monalisa Hui, Shantveer G Uppin, Bala Joseph Stalin, G Sadashivudu   +3 more
doaj   +1 more source

The Robustness of Pathway Analysis in Identifying Potential Drug Targets in Non-Small Cell Lung Carcinoma [PDF]

, 2014
The identification of genes responsible for causing cancers from gene expression data has had varied success. Often the genes identified depend on the methods used for detecting expression patterns, or on the ways that the data had been normalized and ...
Aguilar-Ruiz, Croft, Garnier, González-Barón, Ihaka, Knudsen, Perez-Moreno, Polakis, Smyth, Stekel, Wang, Weinberg, Yu   +12 more
core   +2 more sources

CMTM6: a potential biomarker in non-small cell lung carcinoma

Polish Journal of Pathology
Lung cancer is the most common cause of cancer-related deaths worldwide. With the advent of immunotherapy, programmed cell death-1 and programmed death ligand 1 (PD-L1) inhibitors have gained clinical importance, driving research into their regulatory ...
Seda Tas Ayçiçek, Sıddıka Fındık
doaj   +1 more source

Pneumopericardium as a non-small-cell lung carcinoma complication

Polish Journal of Cardio-Thoracic Surgery, 2016
Below we present a case of a young man with symptoms of progressive weakness, fever, cough, rapid decrease in body weight and the presence of a tumor in the left axillary region. The chest radiography and echocardiography revealed gas bubbles in the pericardium.
Kubisa, Anna, Lesińska, Anna, Dec, Paweł, Szewczak-Głodek, Małgorzata, Kochanowski, Leszek, Kubisa, Bartosz, Feledyk, Grzegorz, Czarnecka, Michalina, Wójcik, Janusz, Grodzki, Tomasz   +9 more
openaire   +2 more sources

Successful treatment with nivolumab for SMARCA4‐deficient non‐small cell lung carcinoma with a high tumor mutation burden: A case report

Thoracic Cancer, 2019
SMARCA4 is a subunit of the switch/sucrose non‐fermentable (SWI/SNF) chromatin‐remodeling complex. An effective treatment for SMARCA4‐deficient non‐small cell lung carcinoma (NSCLC) has not yet been established.
T. Naito, S. Umemura, Hiroshi Nakamura, Y. Zenke, H. Udagawa, K. Kirita, S. Matsumoto, K. Yoh, S. Niho, N. Motoi, K. Aokage, M. Tsuboi, G. Ishii, K. Goto   +13 more
semanticscholar   +1 more source

Study of PD-L1 Expression in Tumours Based on Site and Histology of Tumour – The Experience of a Tertiary Referral Laboratory

Asian Pacific Journal of Cancer Biology, 2023
Background: PD-L1 IHC test is used as a predictive biomarker using FDA-approved assays to select patients likely to benefit from immunotherapy in several advanced-stage tumors. We aim to present our data regarding the prevalence and expression pattern of
Vinita Pant, Munmun Harlalka
doaj   +1 more source

Preferential Localization of MUC1 Glycoprotein in Exosomes Secreted by Non-Small Cell Lung Carcinoma Cells

International Journal of Molecular Sciences, 2019
Lung cancer remains to be the leading cause of cancer-related mortality worldwide. Finding new noninvasive biomarkers for lung cancer is still a significant clinical challenge. Exosomes are membrane-bound, nano-sized vesicles that are released by various
Deng Pan, Jiaxi Chen, C. Feng, Weibo Wu, Yanjin Wang, Jiao Tong, Dapeng Zhou   +6 more
semanticscholar   +1 more source

The Diagnostic Accuracy of Chest CT in the Detection of Tumor and Nodal Status in Non Small Cell Lung Carcinoma [PDF]

, 2003
At this time there is an increasing demand for an accurate pre operative staging in non small cell lung cancer. Chest Computed Tomography (CT) is one of the imaging modality of choice used for this purpose.
Busroh, I. (Ismid), Icksan, A. (Aziza), Syachruddin, E. (Elisna), Yusuf, A. (Anwar)   +3 more
core   +1 more source

Preoperative CYFRA 21-1 and CEA as Prognostic Factors in Patients with Stage I Non-Small Cell Lung Cancer [PDF]

, 2008
Objective: To validate the prognostic value of preoperative levels of CYFRA 21-1, CEA and the corresponding tumor marker index (TMI) in patients with stage I non-small cell lung cancer (NSCLC). Methods: Two hundred forty stage I NSCLC patients (80 in pT1
Ankerst, Donna Pauler, Blankenburg, Florian, Gruber, Christine, Hatz, Rudolf, Nagel, Dorothea, Reinmiedl, Judith, Seidel, Dietrich, Stieber, Petra   +7 more
core   +1 more source

The Gut Microbiome Associates with Immune Checkpoint Inhibition Outcomes in Patients with Advanced Non–Small Cell Lung Cancer

Cancer immunology research, 2020
The gut microbiome influences the efficacy of immune checkpoint inhibition (ICI). In non–small cell lung carcinoma patients, antibiotics have a negative impact on ICI efficacy, correlating to enrichment of Ruminococcaceae UCG 13 and Agathobacter in the ...
T. Hakozaki, C. Richard, A. Elkrief, Y. Hosomi, Myriam Benlaïfaoui, Iris L Mimpen, S. Terrisse, L. Derosa, L. Zitvogel, B. Routy, Y. Okuma   +10 more
semanticscholar   +1 more source