Results 71 to 80 of about 843,078 (353)
Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication. [PDF]
, 2016 The transcription factor Yin Yang 1 (YY1) is frequently overexpressed in cancerous tissues compared to normal tissues and has regulatory roles in cell proliferation, cell viability, epithelial-mesenchymal transition, metastasis and drug/immune resistance.
Bonavida, Benjamin +2 more
core +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Journal of Medical Case Reports, 2011 Introduction Bronchial carcinomas in childhood and adolescence are extremely rare; only individual cases have been reported previously. Case presentation We report on a 16-year-old Caucasian German boy with non-small cell lung carcinoma (squamous cell ...
Haffner Dieter +2 more
doaj +1 more source
Stereotactic ablative radiotherapy for medically inoperable early stage lung cancer: early outcomes [PDF]
, 2012 Objective To evaluate the clinical outcome and safety of stereotactic ablative radiotherapy for medically inoperable stage I non- small-cell lung carcinoma. Design Retrospective case series.
Chan, Connie C C +6 more
core
miR-638 is a new biomarker for outcome prediction of non-small cell lung cancer patients receiving chemotherapy. [PDF]
, 2015 MicroRNAs (miRNAs), a class of small non-coding RNAs, mediate gene expression by either cleaving target mRNAs or inhibiting their translation. They have key roles in the tumorigenesis of several cancers, including non-small cell lung cancer (NSCLC).
Cao, Yan +12 more
core +1 more source
Exosomal proteins as potential diagnostic markers in advanced non-small cell lung carcinoma
Journal of Extracellular Vesicles, 2015 Background Lung cancer is one of the leading causes of cancer-related death. At the time of diagnosis, more than half of the patients will have disseminated disease and, yet, diagnosing can be challenging.
K. R. Jakobsen +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Life Threatening haemoptysis in primary lung cancer-signet ring cell carcinoma
Respiratory Medicine Case Reports, 2020 Primary signet ring cell carcinoma of the lung is a rare non-small cell carcinoma of the lung with extremely aggressive features and poor prognosis. The diagnosis mainly required tissue biopsy with immunohistochemical analysis and gene mutation studies ...
Shamsuddin Anwar +4 more
doaj +1 more source
A Case of Advanced Lung Squamous Cell Carcinoma with CLIP1-ALK Fusion Gene
Chinese Journal of Lung Cancer, 2022 Anaplastic lymphoma kinase (ALK) fusion gene is an important tumor driver gene of non-small cell lung cancer, accounting for about 5% of patients with non-small cell lung cancer, of which 97% are patients with lung adenocarcinoma.
Yue YUAN +4 more
doaj +1 more source
An unusual presentation of non-small cell lung carcinoma
BMJ Case Reports, 2009 Lung cancer is the most common malignancy in the Western world and usually presents with respiratory symptoms. The diagnosis of lung cancer is normally made by chest radiography followed by histological confirmation with either radiological or endoscopically guided biopsies. Very rarely, imaging does not help with the initial diagnosis. Haematuria is a
Mohantha Deevan, Dooldeniya +2 more
openaire +3 more sources