Economic Evaluation of Positron Emission Tomography (PET) in Non Small Cell Lung Cancer (NSCLC), CHERE Working Paper 2007/6 [PDF]
Background: There are several perceived benefits from introducing positron emission tomography (PET) scanning into the staging of non small lung cancer (NSCLC).
Stephen Goodall +2 more
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Aberrant Signaling Pathways in Squamous Cell Lung Carcinoma [PDF]
Lung cancer is the second most commonly occurring non-cutaneous cancer in the United States with the highest mortality rate among both men and women. In this study, we utilized three lung cancer microarray datasets generated by previous researchers to ...
Ting Shi +4 more
core +1 more source
Clinicopathological and Immunohistochemical Analysis of Lung Cancer Biopsies at a Tertiary Care Centre in Central Gujarat, India [PDF]
Introduction: Lung biopsy is a reliable and highly accurate tool for diagnosing and subtyping lung lesions. Two-thirds of lung cancer patients present with advanced disease, and small biopsies remain the main diagnostic tool.
Yogita Vrajlal Kareliya +5 more
doaj +1 more source
Kinetics of 5-aminolevulinic acid-induced fluorescence in organ cultures of bronchial epithelium and tumor [PDF]
Background: 5-Aminolevulinic acid (5-ALA)-induced protoporphyrin IX (PPIX) fluorescence improves the differentiation of tumor and normal tissue in the bladder, skin and brain. Objective: The kinetics of 5-ALA-induced protoporphyrin IX (PPIX) fluorescence
Bergner, Albrecht +8 more
core +1 more source
Gemcitabine Plus Conventional-Dose Epirubicin Versus Gemcitabine Plus Cisplatin as First-Line Chemotherapy for Stage Iiib/Iv Non-Small Cell Lung Carcinoma-a Randomized Phase Ii Trial [PDF]
BACKGROUND: Epirubicin was effective for the treatment of non-small cell lung carcinoma (NSCLC). This study compared the efficacy and safety of gemcitabine plus conventional- dose epirubicin (GE) with gemcitabine- cisplatin (GC) as first-line ...
許駿;郭頌鑫;胡賦强;鄭安理;施金元;余忠仁;林家齊;楊泮池;楊志新 +1 more
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K-Ras and β-catenin mutations cooperate with Fgfr3 mutations in mice to promote tumorigenesis in the skin and lung, but not in the bladder [PDF]
The human fibroblast growth factor receptor 3 (FGFR3) gene is frequently mutated in superficial urothelial cell carcinoma (UCC). To test the functional significance of FGFR3 activating mutations as a ‘driver’ of UCC, we targeted the expression of mutated
Taketo, M.M. +17 more
core +1 more source
Tumor suppressor miR-29c regulates radioresistance in lung cancer cells
Radiotherapy is an important treatment option for non-small cell lung carcinoma patients. Despite the appropriate use of radiotherapy, radioresistance is a biological behavior of cancer cells that limits the efficacy of this treatment.
Elena Arechaga-Ocampo +14 more
doaj +1 more source
Crizotinib in the treatment of non-small-cell lung carcinoma.
Recent studies have demonstrated the benefit of EGFR tyrosine kinase inhibitors in the treatment of advanced non-small-cell lung cancer (NSCLC). The role of activation of the anaplastic lymphoma kinase (ALK) pathway and the presence of the fusion gene EML4-ALK are new molecular targets in studies into the pathogenesis and treatment of NSCLC.
Płużański, Adam +2 more
openaire +2 more sources
PALLIATION AND LIFE QUALITY IN LUNG-CANCER - HOW GOOD ARE CLINICIAN AT JUDGING TREATMENT OUTCOME [PDF]
A recent trial by the MRC Lung Cancer Working Party used physician assessments to compare two palliative schedules of radiotherapy in lung cancer.
Yarnold, J +7 more
core +1 more source
Characterisation and modulation of drug resistance in lung cancer cell lines [PDF]
Chemotherapy drug resistance is a major obstacle in the treatment of cancer. It can result from an increase in levels of cellular drug efflux pumps such as P-glycoprotein (P-gp).
Dunne, Gráinne
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