Results 21 to 30 of about 616,145 (212)
Epigenetics in non-small cell lung carcinomas
Salud Pública de México, 2019 Objective. To perform a systematic review of the main epigenetic aberrations involved in non-small cell lung carcinomas’ (NSCLC) diagnosis, progression, and therapeutics. Materials and methods. We performed a systematic review of the scientific literature on lung cancer epigenetics, focusing on NSCLC. Results.
Irlanda Peralta-Arrieta +3 more
openaire +3 more sources
Tumor Biology, 2017 Epithelial–mesenchymal transition is a crucial event for metastasis and could be mediated by several pathways such as phosphoinositide 3-kinase/Akt, mitogen-activated protein kinases, as well as many epigenetic regulators.
Hakan Kucuksayan, Hakan Akca
doaj +1 more source
KAN0438757: a novel PFKFB3 inhibitor that induces programmed cell death and suppresses cell migration in non-small cell lung carcinoma cells . [PDF]
Biotechnologia Acta, 2023 Aim. PFKFB3 is glycolytic activators that is overexpressed in human lung cancer and plays a crucial role in multiple cellular functions including programmed cell death.
Deniz Özdemir +2 more
doaj
Radiofrequency Ablation of Lung Cancer at Okayama University Hospital: A Review of 10 Years of Experience [PDF]
, 2011 The application of radiofrequency ablation for the treatment of lung cancer by our group at Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences began in June 2001, and in the present report, we review our 10-year ...
Fujiwara, Hiroyasu +12 more
core +1 more source
TTF-1/p63-positive poorly differentiated NSCLC: A histogenetic hypothesis from the basal reserve cell of the terminal respiratory unit [PDF]
, 2020 TTF-1 is expressed in the alveolar epithelium and in the basal cells of distal terminal bronchioles. It is considered the most sensitive and specific marker to define the adenocarcinoma arising from the terminal respiratory unit (TRU). TTF-1, CK7, CK5/6,
Barraco N. +8 more
core +1 more source
Sleeve segmentectomy for non–small cell lung carcinoma [PDF]
The Journal of Thoracic and Cardiovascular Surgery, 2004 Although sleeve segmentectomy for centrally located lung cancers was originally designed for patients unable to tolerate lobectomy, we have tried it in patients with noncompromised function as well. We evaluated the efficiency of this atypical type of bronchoplasty.Of 202 patients for whom we performed bronchoplasty for primary non-small cell lung ...
Okada, Morihito +6 more
openaire +2 more sources
Tumor Biology, 2017 Abnormal expression of microRNAs has been reported to regulate gene expression and cancer cell growth, invasion, and migration. Recently, upregulation of hsa-miR-1285 was demonstrated in bronchoalveolar lavage fluid samples from patients with lung cancer
Shixia Zhou +4 more
doaj +1 more source
EGFR mutation testing in non-small cell lung cancer (NSCLC)
Journal of Infection and Public Health, 2012 Summary: Lung carcinoma is subdivided into small cell carcinoma and non-small cell carcinoma (NSCLC). NSCLC is heterogeneous group of carcinomas and accounts for 70–80% of lung cancer. NSCLC is further divided into adenocarcinoma, squamous cell carcinoma,
Fouad Al Dayel
doaj +1 more source
Pinpointing pin1 in non-small cell lung carcinoma [PDF]
Cancer Biology & Therapy, 2010 Factors that promote tumorigenesis encompass a wide array of proteins that include transcription factors, signal transduction molecules, negative regulators of tumor suppressors, transmembrane receptors and enzymes involved in a variety of processes. Identifying these factors remains one of the most pertinent issues in cancer research, as they can be ...
Joseph, Catanzaro, Wei-Xing, Zong
openaire +2 more sources
The Robustness of Pathway Analysis in Identifying Potential Drug Targets in Non-Small Cell Lung Carcinoma [PDF]
, 2014 The identification of genes responsible for causing cancers from gene expression data has had varied success. Often the genes identified depend on the methods used for detecting expression patterns, or on the ways that the data had been normalized and ...
Aguilar-Ruiz +12 more
core +2 more sources