Results 31 to 40 of about 615,884 (310)

Plasma lipid biomarker signatures in squamous carcinoma and adenocarcinoma lung cancer patients [PDF]

, 2015
There is a clinical need for reliable biomarkers for lung cancer that permit early diagnosis of the disease and provide prediction of histological phenotype.
AG Serrano, AM Fiorenza, Andrew W. Fogarty, CH Oak, D Kong, David A. Barrett, David R. Baldwin, E Wojcik, GL May, H Ulmer, H Yang, Helen L. Barr, J Castro de, J Chee, J Dong, J Liu, JM Poczobutt, K Yanagisawa, K Yang, L Cheng, M Haag, M Hassanein, M Hassanein, M Murphy, MJ Wakelam, MR Wenk, P Brites, R Angelis de, RA Murphy, RA Murphy, RE Smith, RL Keith, RT Sreseli, S Cedres, Srinivasarao Ravipati, WJ Scott, X Gao, X Zeng, Y Guo, YY Tyurina, ZA Fernandis   +40 more
core   +1 more source

Durable response to durvalumab‐based immunochemotherapy in small‐cell lung carcinoma transformation from EGFR‐mutant non–small cell lung cancer: A case report

Thoracic Cancer, 2022
Combined small‐cell lung carcinoma (C‐SCLC) is small‐cell lung carcinoma (SCLC) with added non–small‐cell morphology. We report a case of epidermal growth factor receptor (EGFR) mutation‐positive C‐SCLC in an 84‐year‐old patient with metastatic brain ...
Yu‐Chung Li
doaj   +1 more source

Overexpression of the non-coding SOX2OT variants 4 and 7 in lung tumors suggests an oncogenic role in lung cancer [PDF]

, 2016
Despite the advances in cancer therapy, lung cancer still remains the most leading cause of cancer death worldwide. The long non-coding RNAs (lncRNAs) are recently introduced as novel regulators of human cancers. SOX2 overlapping transcript (SOX2OT) is a
Ghanei, M., Mowla, S.J., Saghaeian Jazi, M., Samaei, N.M., Shadmehr, M.B.   +4 more
core   +1 more source

Pinpointing pin1 in non-small cell lung carcinoma [PDF]

Cancer Biology & Therapy, 2010
Factors that promote tumorigenesis encompass a wide array of proteins that include transcription factors, signal transduction molecules, negative regulators of tumor suppressors, transmembrane receptors and enzymes involved in a variety of processes. Identifying these factors remains one of the most pertinent issues in cancer research, as they can be ...
Joseph, Catanzaro, Wei-Xing, Zong
openaire   +2 more sources

KAN0438757: a novel PFKFB3 inhibitor that induces programmed cell death and suppresses cell migration in non-small cell lung carcinoma cells . [PDF]

Biotechnologia Acta, 2023
Aim. PFKFB3 is glycolytic activators that is overexpressed in human lung cancer and plays a crucial role in multiple cellular functions including programmed cell death.
Deniz Özdemir, Seher Saruhan, Can Ali Agca   +2 more
doaj  

Sleeve segmentectomy for non–small cell lung carcinoma [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2004
Although sleeve segmentectomy for centrally located lung cancers was originally designed for patients unable to tolerate lobectomy, we have tried it in patients with noncompromised function as well. We evaluated the efficiency of this atypical type of bronchoplasty.Of 202 patients for whom we performed bronchoplasty for primary non-small cell lung ...
Okada, Morihito, Nishio, Wataru, Sakamoto, Toshihiko, Uchino, Kazuya, Yuki, Tsuyoshi, Nakagawa, Akio, Tsubota, Noriaki   +6 more
openaire   +2 more sources

MicroRNA-1285-5p influences the proliferation and metastasis of non-small-cell lung carcinoma cells via downregulating CDH1 and Smad4

Tumor Biology, 2017
Abnormal expression of microRNAs has been reported to regulate gene expression and cancer cell growth, invasion, and migration. Recently, upregulation of hsa-miR-1285 was demonstrated in bronchoalveolar lavage fluid samples from patients with lung cancer
Shixia Zhou, Zhongmian Zhang, Pengyuan Zheng, Wenchao Zhao, Na Han   +4 more
doaj   +1 more source

Perioperative detection of circulating tumour cells in patients with lung cancer [PDF]

, 2017
© 2017 Chudasama et al. Lung cancer is a leading cause of mortality and despite surgical resection a proportion of patients may develop metastatic spread.
Alexandra Rice, Cohen, Cristofanilli, Delloye-Bourgeois, Desitter, Dimple Chudasama, Emmanouil Karteris, Fidler, Fidler, Hashimoto, Hayes, Hiltermann, Hou, Julie Beeson, Karl, Krebs, Krebs, Lee, Munzone, Nagrath, Nathan Burnside, Scheinin, Vladimir Anikin, Yao, Zhang   +24 more
core   +1 more source

The crosstalk between p38 and Akt signaling pathways orchestrates EMT by regulating SATB2 expression in NSCLC cells

Tumor Biology, 2017
Epithelial–mesenchymal transition is a crucial event for metastasis and could be mediated by several pathways such as phosphoinositide 3-kinase/Akt, mitogen-activated protein kinases, as well as many epigenetic regulators.
Hakan Kucuksayan, Hakan Akca
doaj   +1 more source

EGFR mutation testing in non-small cell lung cancer (NSCLC)

Journal of Infection and Public Health, 2012
Summary: Lung carcinoma is subdivided into small cell carcinoma and non-small cell carcinoma (NSCLC). NSCLC is heterogeneous group of carcinomas and accounts for 70–80% of lung cancer. NSCLC is further divided into adenocarcinoma, squamous cell carcinoma,
Fouad Al Dayel
doaj   +1 more source