EGFR mutation testing in non-small cell lung cancer (NSCLC)
Summary: Lung carcinoma is subdivided into small cell carcinoma and non-small cell carcinoma (NSCLC). NSCLC is heterogeneous group of carcinomas and accounts for 70–80% of lung cancer. NSCLC is further divided into adenocarcinoma, squamous cell carcinoma,
Fouad Al Dayel
doaj +1 more source
Oncogenic circRNA C190 Promotes Non–Small Cell Lung Cancer via Modulation of the EGFR/ERK Pathway
The circRNA C190 is identified as a mediator of multiple pro-oncogenic signaling pathways in lung cancer and can be targeted to suppress tumor progression. Lung cancers are the leading cause of cancer-related mortality worldwide, and the majority of lung
A. A. Ishola +16 more
semanticscholar +1 more source
The Robustness of Pathway Analysis in Identifying Potential Drug Targets in Non-Small Cell Lung Carcinoma [PDF]
The identification of genes responsible for causing cancers from gene expression data has had varied success. Often the genes identified depend on the methods used for detecting expression patterns, or on the ways that the data had been normalized and ...
Aguilar-Ruiz +12 more
core +2 more sources
Radiofrequency Ablation of Lung Cancer at Okayama University Hospital: A Review of 10 Years of Experience [PDF]
The application of radiofrequency ablation for the treatment of lung cancer by our group at Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences began in June 2001, and in the present report, we review our 10-year ...
Fujiwara, Hiroyasu +12 more
core +1 more source
Changing trends in incidence of lung cancer by histological type in Montenegro [PDF]
Introduction. Lung cancer is one of the most common malignant neoplasms, as well as the most common cause of death cancer. Most lung cancers are squamous cell carcinomas, small cell carcinomas or adenocarcinomas. Objective.
Medenica Milić +4 more
doaj +1 more source
RET in non-small cell lung carcinoma
The advent of stratified medicine and tailored therapies has caused non-small cell lung cancer (NSCLC) to become a subject of keen interest, with an emphasis on comprehensive genomic testing for driver mutations and biomarkers. The rearranged during transfection (RET) gene rearrangement has been observed in 1%–2% of all NSCLCs.
Shrinidhi Nathany +2 more
openaire +1 more source
SMARCA4 is a subunit of the switch/sucrose non‐fermentable (SWI/SNF) chromatin‐remodeling complex. An effective treatment for SMARCA4‐deficient non‐small cell lung carcinoma (NSCLC) has not yet been established.
T. Naito +13 more
semanticscholar +1 more source
Lung cancer: risk factors, management, and prognosis [PDF]
Lung cancer or lung tumor the most common cause of cancer death in men and second most common in women after breast cancer. Highest rates in North America, Europe, and East Asia, with one third of new cases in China, lower rates in Africa and South Asia.
A. Nazirah +5 more
core +1 more source
Trop2 and its overexpression in cancers: regulation and clinical/therapeutic implications. [PDF]
Trop2 is a transmembrane glycoprotein encoded by the Tacstd2 gene. It is an intracellular calcium signal transducer that is differentially expressed in many cancers. It signals cells for self-renewal, proliferation, invasion, and survival.
Bonavida, Benjamin, Shvartsur, Anna
core +9 more sources
A Case Report of Small Cell Lung Carcinoma in a Patient with Progressive Diffuse Sclerosis
Connective tissue diseases, including scleroderma, may be associated with an increased risk of lung cancer. The most common type of lung cancer associated with systemic sclerosis is adenocarcinoma or bronchoalveolar carcinoma, and small cell carcinoma is
Hojatolah Ghorbani +4 more
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