Results 41 to 50 of about 689,752 (349)

KAN0438757: a novel PFKFB3 inhibitor that induces programmed cell death and suppresses cell migration in non-small cell lung carcinoma cells . [PDF]

Biotechnologia Acta, 2023
Aim. PFKFB3 is glycolytic activators that is overexpressed in human lung cancer and plays a crucial role in multiple cellular functions including programmed cell death.
Deniz Özdemir, Seher Saruhan, Can Ali Agca   +2 more
doaj  

Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non-Small Cell Lung Carcinoma and Mesothe

Advances in Anatomic Pathology, 2017
Assessment of the immune response to tumors is growing in importance as the prognostic implications of this response are increasingly recognized, and as immunotherapies are evaluated and implemented in different tumor types.
S. Hendry, R. Salgado, T. Gevaert, P. Russell, T. John, T. John, B. Thapa, M. Christie, K. V. D. Vijver, M. V. Estrada, Paula I. Gonzalez-Ericsson, M. Sanders, B. Solomon, C. Solinas, G. V. D. Eynden, Y. Allory, Y. Allory, M. Preusser, J. Hainfellner, G. Pruneri, A. Vingiani, S. Demaria, F. Symmans, P. Nuciforo, L. Comerma, E. Thompson, S. Lakhani, S. Lakhani, Seong-Rim Kim, S. Schnitt, C. Colpaert, C. Sotiriou, S. Scherer, M. Ignatiadis, S. Badve, R. Pierce, G. Viale, N. Sirtaine, F. Penault-Llorca, Tomohagu Sugie, S. Fineberg, S. Paik, A. Srinivasan, A. Richardson, Yihong Wang, Yihong Wang, E. Chmielik, J. Brock, Douglas B. Johnson, J. Balko, S. Wienert, V. Bossuyt, S. Michiels, N. Ternès, N. Burchardi, S. Luen, S. Luen, P. Savas, P. Savas, F. Klauschen, P. Watson, B. Nelson, B. Nelson, C. Criscitiello, S. O'toole, D. Larsimont, R. Wind, G. Curigliano, F. André, M. Lacroix-Triki, Mark van de Vijver, F. Rojo, G. Floris, S. Bedri, J. Sparano, D. Rimm, T. Nielsen, Z. Kos, S. Hewitt, Baljit Singh, G. Farshid, S. Loibl, K. Allison, N. Tung, S. Adams, K. Willard-Gallo, H. Horlings, L. Gandhi, L. Gandhi, Andre Moreira, F. Hirsch, M. Dieci, M. Urbanowicz, I. Brčić, Konstanty Korski, F. Gaire, H. Koeppen, A. Lo, A. Lo, J. Giltnane, M. Rebelatto, K. Steele, J. Zha, K. Emancipator, J. Juco, C. Denkert, J. Reis-Filho, S. Loi, S. Fox   +108 more
semanticscholar   +1 more source

Exploiting metabolic vulnerabilities of Non small cell lung carcinoma

Seminars in Cell & Developmental Biology, 2020
Lung cancer is the main cause of cancer death worldwide. Non-Small Cell Lung Carcinoma (NSCLC) is the most common subtype of lung cancer, and the prognosis of NSCLC patients in advanced stages is still very poor. Given the need for new therapies, the metabolism of NSCLC has been widely studied in the past two decades to identify vulnerabilities that ...
Majem, Blanca, Nadal, Ernest, Muñoz Pinedo, Cristina   +2 more
openaire   +4 more sources

Genetic variant of miR-4293 rs12220909 is associated with susceptibility to non-small cell lung cancer in a Chinese Han population. [PDF]

PLoS ONE, 2017
Non-small cell lung cancer is one of the most common cancers and the leading cause of cancer death worldwide. Genetic variants in regulatory regions of some miRNAs might be involved in non-small cell lung cancer susceptibility and survival. rs12220909 (G/
Lixia Fan, Linqi Chen, Xiaoling Ni, Shicheng Guo, Yinghui Zhou, Chenji Wang, Yabiao Zheng, Fangyuan Shen, Vijay Kumar Kolluri, Merlin Muktiali, Zhenhong Zhao, Junjie Wu, Dunmei Zhao, Zhenglei He, Xulong Feng, Ziyu Yuan, Juan Zhang, Li Jin, Jiucun Wang, Minghua Wang   +19 more
doaj   +1 more source

Successful treatment with nivolumab for SMARCA4‐deficient non‐small cell lung carcinoma with a high tumor mutation burden: A case report

Thoracic Cancer, 2019
SMARCA4 is a subunit of the switch/sucrose non‐fermentable (SWI/SNF) chromatin‐remodeling complex. An effective treatment for SMARCA4‐deficient non‐small cell lung carcinoma (NSCLC) has not yet been established.
T. Naito, S. Umemura, Hiroshi Nakamura, Y. Zenke, H. Udagawa, K. Kirita, S. Matsumoto, K. Yoh, S. Niho, N. Motoi, K. Aokage, M. Tsuboi, G. Ishii, K. Goto   +13 more
semanticscholar   +1 more source

MicroRNA-1285-5p influences the proliferation and metastasis of non-small-cell lung carcinoma cells via downregulating CDH1 and Smad4

Tumor Biology, 2017
Abnormal expression of microRNAs has been reported to regulate gene expression and cancer cell growth, invasion, and migration. Recently, upregulation of hsa-miR-1285 was demonstrated in bronchoalveolar lavage fluid samples from patients with lung cancer
Shixia Zhou, Zhongmian Zhang, Pengyuan Zheng, Wenchao Zhao, Na Han   +4 more
doaj   +1 more source

"Person in the barrel" syndrome: Unusual heralding presentation of squamous cell carcinoma of the lung

Annals of Indian Academy of Neurology, 2016
Paraneoplastic neurological syndromes (PNS) are rare and relatively unusual in day to day clinical practice. Occasionally, PNS may be the heralding manifestation of the malignancy.
Rajesh Verma, Rakesh Lalla, Tushar B Patil, Suresh Babu   +3 more
doaj   +1 more source

Changing trends in incidence of lung cancer by histological type in Montenegro [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2014
Introduction. Lung cancer is one of the most common malignant neoplasms, as well as the most common cause of death cancer. Most lung cancers are squamous cell carcinomas, small cell carcinomas or adenocarcinomas. Objective.
Medenica Milić, Medenica Miraš, Bojović Olivera, Soldatović Ivan, Durutović Ivana   +4 more
doaj   +1 more source

Using VGG16 Algorithms for classification of lung cancer in CT scans Image [PDF]

arXiv, 2023
Lung cancer is the leading reason behind cancer-related deaths within the world. Early detection of lung nodules is vital for increasing the survival rate of cancer patients. Traditionally, physicians should manually identify the world suspected of getting carcinoma.
arxiv  

Preferential Localization of MUC1 Glycoprotein in Exosomes Secreted by Non-Small Cell Lung Carcinoma Cells

International Journal of Molecular Sciences, 2019
Lung cancer remains to be the leading cause of cancer-related mortality worldwide. Finding new noninvasive biomarkers for lung cancer is still a significant clinical challenge. Exosomes are membrane-bound, nano-sized vesicles that are released by various
Deng Pan, Jiaxi Chen, C. Feng, Weibo Wu, Yanjin Wang, Jiao Tong, Dapeng Zhou   +6 more
semanticscholar   +1 more source