Results 111 to 120 of about 361,742 (335)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Controversies in the efficacy of adjuvant chemotherapy in different epithelial ovarian carcinoma histologies

open access: yesJournal of Oncological Sciences, 2019
Aim: In this retrospective study, the efficacy of adjuvant chemotherapy and its contribution to prognosis were investigated in patients diagnosed with different subgroups of ovarian carcinoma at stages 1–3.
Ece Esin   +5 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Clinical implication for endometriosis associated with ovarian cancer

open access: yesGynecology and Minimally Invasive Therapy, 2017
We reviewed current literature regarding the association of endometriosis and epithelial ovarian cancer based on epidemiology studies, molecular researches and clinical observations. Our methods include a review of literature research of MEDLINE, PubMed,
Pao-Ling Torng
doaj   +1 more source

Quantifying cancer epithelial-mesenchymal plasticity and its association with stemness and immune response

open access: yes, 2019
Cancer cells can acquire a spectrum of stable hybrid epithelial/mesenchymal (E/M) states during epithelial-mesenchymal transition (EMT). Cells in these hybrid E/M phenotypes often combine epithelial and mesenchymal features and tend to migrate ...
Bocci, Federico   +7 more
core   +1 more source

Recent Advancements in Prognostic Factors of Epithelial Ovarian Carcinoma

open access: yesInternational Scholarly Research Notices, 2014
Ovarian cancer remains the most common cause of gynecologic cancer-related death among women in developed countries. Nevertheless, subgroups of ovarian cancer patients experience relatively longer survival.
Mohammad Ezzati   +7 more
semanticscholar   +1 more source

From Backpain to Paraplegia: A Rare Primary Presentation of Metastatic Ovarian Cancer in Pregnancy

open access: yesGynecology Obstetrics & Reproductive Medicine, 2011
Vertebral metastasis from epithelial ovarian carcinoma is extremely rare and usually diagnosed at autopsy. We present here an unusual case of pregnant woman who developed paraplegy, due to thoracal vertebral metastasis and pathologic vertebral fracture ...
Filiz Çayan   +5 more
doaj  

Ovarian cancer statistics, 2018

open access: yesCa, 2018
In 2018, there will be approximately 22,240 new cases of ovarian cancer diagnosed and 14,070 ovarian cancer deaths in the United States. Herein, the American Cancer Society provides an overview of ovarian cancer occurrence based on incidence data from ...
Lindsey A. Torre   +8 more
semanticscholar   +1 more source

Ultrasound in Women's Health: Mechanisms, Applications, and Emerging Opportunities

open access: yesAdvanced Materials, EarlyView.
As healthcare moves toward decentralization, ultrasound technologies are evolving from strictly imaging tools in clinical settings into versatile diagnostic and therapeutic platforms, with growing roles addressing women's health needs. This review highlights how ultrasound's underlying physical mechanisms can be harnessed to reduce disparities in women'
Sarah B. Ornellas   +7 more
wiley   +1 more source

Ovarian Carcinosarcoma and Its Association with Mature Cystic Teratoma and Primary Tubal Carcinoma

open access: yesCase Reports in Pathology, 2016
Introduction. Carcinosarcoma is an uncommon form of ovarian cancers, classified as being part of the group of mixed epithelial and mesenchymal tumors.
Sunida Rewsuwan   +3 more
doaj   +1 more source

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