Results 261 to 270 of about 361,742 (335)

Cancer‐Specific Antihuman Podoplanin Antibody chLpMab‐2f Exerts Antitumor Effects Against Pleural Mesothelioma

open access: yesCancer Science, EarlyView.
Cancer‐specific antihuman podoplanin antibody chLpMab‐2f exerted antibody‐dependent cellular cytotoxicity and complement‐dependent cytotoxicity against pleural mesothelioma (PM) cell lines. Additionally, chLpMab‐2f inhibited tumor progression in mice with subcutaneously and intrathoracically transplanted human PM cells.
Aito Yoshida   +15 more
wiley   +1 more source

Roles of TIF1β in Leukemic Stem Cell Through SETDB1‐Dependent and Independent Mechanisms

open access: yesCancer Science, EarlyView.
In leukemic stem cell, BCR::ABL cooperates with TIF1β to open chromatin at oncogenes and close chromatin at differentiation regulators, driving leukemic reprogramming. In TIF1β‐deficient stem cell, the loss of TIF1β inverts this balance, showing closed chromatin at oncogenes and open chromatin at differentiation regulators.
Mariko Morii, Sho Kubota, Goro Sashida
wiley   +1 more source

ZNF844 Suppresses Invasion and Metastasis in Nasopharyngeal Carcinoma by Inhibiting the PI3K‐AKT Signaling Pathway

open access: yesCancer Science, EarlyView.
ZNF844 functions as a tumor suppressor in NPC by inhibiting invasion and metastasis through regulation of the PI3K‐AKT signaling pathway. It may serve as a promising therapeutic target and prognostic biomarker for NPC. ABSTRACT Epigenetic regulation plays a crucial role in the development of nasopharyngeal carcinoma (NPC).
Jinping Xu   +7 more
wiley   +1 more source

From Inflammation to Malignancy: The Link Between Endometriosis and Gynecological Cancers. [PDF]

open access: yesInt J Mol Sci
Kłodnicka K   +9 more
europepmc   +1 more source

AllergoOncology in Review: Harnessing Allergy in the Field of Oncology to Improve Patient Outcomes

open access: yesClinical &Experimental Allergy, EarlyView.
ABSTRACT The AllergoOncology field brings together the study of allergic and cancer immune responses, having evolved from early epidemiological studies that reported inverse associations between allergies, IgE and cancer risk. Insights from studying allergic inflammation are revealing previously unappreciated immune mechanisms that confer protective ...
Jakub Zydron   +13 more
wiley   +1 more source

DNA-Based Liquid Biopsy for Evaluating Surgical and Postsurgical Outcomes in Gynecologic Malignancies: A Systematic Review. [PDF]

open access: yesJ Clin Lab Anal
Yavari S   +13 more
europepmc   +1 more source

Mechanistic Insights Into Recurrent Implantation Failure: The Lactate–H3K18la–SLC7A11 Axis Explored via Endometrial Organoid and Blastoid–Endometrial Cell Implantation Models

open access: yesCell Proliferation, EarlyView.
Clinical samples first revealed impaired lactate synthesis in RIF patients. Subsequently, using endometrial organoids and a blastoid‐endometrial cell implantation model, we demonstrated that lactate enhances endometrial receptivity via H3K18la‐mediated SLC7A11 activation.
Lingling Dong   +9 more
wiley   +1 more source

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