Results 291 to 300 of about 361,742 (335)

Farletuzumab in epithelial ovarian carcinoma

Expert Opinion on Biological Therapy, 2010
Ovarian cancer is the leading cause of death from a gynecologic malignancy. Recurrence is both common and lethal, necessitating the development of novel targeted therapies. Farletuzumab (MORAb-003) is a humanized mAb with high affinity for folate receptor alpha (FRalpha), a 38 kDa GPI-anchored protein that is overexpressed in 90% of epithelial ovarian ...
Whitney A, Spannuth, Anil K, Sood, Robert L, Coleman   +2 more
openaire   +2 more sources

METTL3 promotes ovarian carcinoma growth and invasion through the regulation of AXL translation and epithelial to mesenchymal transition.

Gynecologic Oncology, 2018
OBJECTIVE As the most prevalent internal modification in mammalian messenger RNA, N6‑methyladenosine (m6A) plays an important role in posttranscriptional gene regulation.
Wenfeng Hua, Yuan Zhao, Xiaohan Jin, Danyang Yu, Jing He, D. Xie, P. Duan   +6 more
semanticscholar   +1 more source

Primary chemotherapy of epithelial ovarian carcinoma

Seminars in Surgical Oncology, 1994
AbstractThis review provides a perspective on primary chemotherapeutic approaches in epithelial ovarian cancer. Chemotherapy is not recommended in grade 1 or 2 stage i‐a or b. In other early‐stage cases, postoperative melphalan or intraperitoneal radioactive phosphorus remain standard of care, even though these treatments have not been shown in a ...
G A, Omura, B S, Siller
openaire   +2 more sources

Salvage Chemotherapy for Epithelial Ovarian Carcinoma

Gynecologic Oncology, 1994
Advanced epithelial ovarian cancer is a highly chemosensitive solid tumor with response rates of 70-80% to first-line chemotherapy, including a high proportion of complete responses. The majority of patients, however, eventually relapse and ultimately die of chemoresistant disease.
M C, Christian, E L, Trimble
openaire   +2 more sources

Chemotherapy for advanced epithelial ovarian carcinoma

Best Practice & Research Clinical Obstetrics & Gynaecology, 2002
Advanced epithelial ovarian cancer (AOC) is the most common clinical presentation of ovarian cancer. Virtually all patients will require some form of chemotherapy with curative or palliative intent. Prognostic factors, first- and second-line therapy, as well as experimental approaches for AOC are reviewed.
Nelson Gustavo Neder, Kalil, William Patrick, McGuire   +1 more
openaire   +2 more sources

Brain Metastases in Epithelial Ovarian Carcinoma

Gynecologic Oncology, 1995
Central nervous system metastases from epithelial ovarian carcinoma are uncommon. A retrospective study was undertaken to see if there was a difference in brain metastases from ovarian cancer in our patient population as compared to the literature. A retrospective study of all patients diagnosed with brain metastases from epithelial ovarian carcinoma ...
J P, Geisler, H E, Geisler
openaire   +2 more sources

Bone metastasis in epithelial ovarian carcinoma

International Journal of Gynecology & Obstetrics, 1996
Two cases of bone metastasis in patients with epithelial ovarian carcinoma and a review of the literature are presented. Bone metastases detected antemortem are rare and herald a poor prognosis.
T V, Dinh, B L, Liebowitz, E V, Hannigan, V J, Schnadig, M G, Doherty   +4 more
openaire   +2 more sources

Epithelial Ovarian Carcinoma and Fertility of Parents

Epidemiology, 2002
We studied the fertility of the parents of 163 women with epithelial ovarian carcinoma in two hospitals in New York City, compared with the parents of 159 controls from similar neighborhoods. We used unconditional logistic regression to control for covariates, including parity, oral contraceptive use, age at menarche, and Jewish ancestry. Compared with
Victor, Siskind, David, Purdie, David, Whiteman, Adele, Green   +3 more
  +6 more sources

Advanced epithelial ovarian carcinoma during pregnancy

International Journal of Clinical Oncology, 2007
We report a rare case of advanced ovarian mucinous adenocarcinoma in a pregnant woman. A 28-year-old pregnant Japanese woman was diagnosed with an ovarian tumor 8 cm in diameter at a local hospital. She was sent to a private hospital at 25 weeks of gestation because of the growing ovarian tumor. Advanced ovarian carcinoma with widespread intraabdominal
Shin-ichi, Ishioka, Takuhiro, Hayashi, Toshiaki, Endo, Tsuyoshi, Baba, Hiroyuki, Honma, Tsuyoshi, Saito   +5 more
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Bone metastasis from epithelial ovarian carcinoma

The Lancet Oncology, 2002
THE LANCET Oncology Vol 3 August 2002 http://oncology.thelancet.com 513 47 Tu S-M, Reyes A, Troncoso P, et al. Prostate cancer with testicular or penile metastases: clinical, pathological, and immunohistochemical features. Cancer, in press. 48 Arber DA, Tamayo R, Weiss LM.
Petty, Russell D., Gilbert, Fiona, Hutcheon, Andrew W., Sarkar, Tarun K., McNally, Orla, Parkin, David   +5 more
openaire   +3 more sources