Results 161 to 170 of about 89,882 (308)

miRNA Profiling of Cholesteatoma‐Derived Exosomes Reveals Exosomal miR‐223‐3p and miR‐142‐5p as Potential Biomarkers for Acquired Middle Ear Cholesteatoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Acquired cholesteatoma is an abnormal and invasive growth of keratinized squamous epithelial cells in the middle ear. The study aims to explore the role of exosomal miRNAs in the pathogenesis of acquired cholesteatoma and their potential in clinical application.
Qi Tang, Meng‐Yao Xie, Shu Wang, Zhi‐Yuan Wu, Zhi‐Jin Han, Chen Li, Shu‐Yi Wang, Yuan Cao, Yu‐Run Chen, Bin Wang, Ying‐Ying Shang, Xiao‐Wu Huang, Hua Yang   +12 more
wiley   +1 more source

Contrast-enhanced ultrasound as a non-invasive diagnostic modality for pancreatic ductal adenocarcinoma: The question of Ki67 for study validation. [PDF]

World J Gastrointest Oncol
Moyana TN.
europepmc   +1 more source

Does Adjuvant Therapy in Invasive Intraductal Papillary Mucinous Neoplasm of the Pancreas Improve Survival? A Systematic Review and Meta‐Analysis Using Trial Sequential Analysis

World Journal of Surgery, EarlyView.
Question: What is the efficacy of adjuvant therapy in resected invasive IPMN? Findings: This meta‐analysis showed that patients with invasive IPMN do not benefit from adjuvant therapy (HR 1.21, 95% IC: 0.81−1.79). A subgroup analysis showed that node‐positive patients have an improved OS (HR 1.86; 95% CI 1.39; 2.47, p < 0.001).
Carlo Ingaldi, Vincenzo D'Ambra, Claudio Ricci, Laura Alberici, Marina Migliori, Mariacristina Di Marco, Andrea Palloni, Cristina Mosconi, Carla Serra, Riccardo Casadei   +9 more
wiley   +1 more source

SEER-based hypothesis-generating research for minimum lymph node evaluation in early-stage pancreatic ductal adenocarcinoma patients. [PDF]

Front Surg
Xu H, Huang H, Yan A, Li R, Xiao E, Wang H, Wang Y, Ge T, Huang G.   +8 more
europepmc   +1 more source

Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer‐related death in children and adolescents. Five‐year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the
Luke R. Holmes, Rishi S. Kotecha, Derek J. Roebuck   +2 more
wiley   +1 more source

Evaluation of pancreatic adenocarcinoma with tumor budding and lymphocytic infiltration as prognostic marker. [PDF]

World J Gastrointest Oncol
Jagtap SV, Jagtap SS.
europepmc   +1 more source

Defining an Unresectable Primary Retroperitoneal Sarcoma

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Retroperitoneal sarcomas (RPS) comprise a heterogenous group of rare mesenchymal tumours. A complete macroscopic en bloc resection of the tumour with involved adjacent structures is the only curative treatment modality. There remain no consensus criteria regarding the definition of a resectable versus unresectable RPS.
James Tai, Eyal Mor, Catherine Mitchell, Kwang Chin, Stephen Schlicht, Hayden Snow, David E. Gyorki   +6 more
wiley   +1 more source

Case Report: Metachronous pancreatic adenocarcinoma following HER2-positive breast cancer and the implications of non-BRCA germline variants with TP53-mutant disease. [PDF]

Front Oncol
Chen J, Zhou HC, Fan MH, Qin MY.
europepmc   +1 more source

A Combinatorial Effect of Immune Checkpoint Inhibitors and CD40 Agonistic Antibody in Murine Pancreatic Cancer Model

Cancer Science, EarlyView.
We established and extensively analyzed an organoid‐based mouse model that closely mimics human pancreatic ductal adenocarcinoma. Monotherapy with an immune checkpoint inhibitor cocktail or a CD40 agonist antibody showed minimal efficacy. However, combining both reagents produced a strong synergistic effect by enhancing anti‐tumor immunity.
Juri Ichikawa, Hiroshi Okuda, Kuniyuki Kawano, Shingo Kato, Shinya Sato, Ryo Kuroishikawa, Daisuke Kurotaki, Wataru Kawase, Haruka Yoshida, Yukihiko Hiroshima, Itaru Endo, Shin Maeda, Tomohiko Tamura   +12 more
wiley   +1 more source

Unveiling GDF15 as a promising biomarker for predicting survival in pancreatic ductal carcinoma: a retrospective research. [PDF]

BMC Cancer
Xiao J, Lu X, Luo W, Wang Y, Zhang T.
europepmc   +1 more source