Results 211 to 220 of about 425,528 (280)

Primary Renal Small Cell Neuroendocrine Carcinoma With Inferior Vena Cava Tumor Thrombus: A Report of a Rare Case. [PDF]

Cureus
Nguyen DT, Nguyen HX, Hoang PT.
europepmc   +1 more source

Approaches to repurposing reverse transcriptase antivirals in cancer

British Journal of Clinical Pharmacology, EarlyView.
This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head, Saiful Islam, Jennifer H. Martin   +2 more
wiley   +1 more source

Trends and hotspots in targeted therapy resistance research for renal cell carcinoma: a bibliometric and visualization analysis. [PDF]

Discov Oncol
Wang Z, Xie X, Wang Z, Tang P, Chen J, Xu J, Zhang J, Xiao H, Zheng C, Jiang J, Liu Q, Lan W.   +11 more
europepmc   +1 more source

Pharmacokinetics, pharmacodynamics and safety of casdatifan, a novel hypoxia‐inducible factor‐2α inhibitor, in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims Casdatifan is an orally bioavailable small‐molecule hypoxia‐inducible factor‐2α (HIF‐2α) inhibitor currently in development for treating patients with clear cell renal cell carcinomas. The aim of this study was to characterize the pharmacokinetics (PK), pharmacodynamics and safety of casdatifan in healthy participants.
Mohammad Ghasemi, Ji Yun Kim, Lisa Seitz, Lixia Jin, Paul G. Foster, Kai H. Liao, Tzuling Cheng, Elaine Paterson, Maria Velinova, Nicole Rivera Rosario, Reza Khosravan, Balaji Agoram   +11 more
wiley   +1 more source

Robust response to pembrolizumab plus lenvatinib in a patient with renal cell carcinoma with rhabdoid features: A case report. [PDF]

Urol Case Rep
Yamamoto S, Fukata S, Karashima T, Kurabayashi A, Yoshimura R, Furihata K, Shiba Y, Nao T, Satake H, Inoue K.   +9 more
europepmc   +1 more source

Engineering antibodies with cancer‐associated binding sites

BMEMat, EarlyView.
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian, Yumeng Pan, Yingchun Zhang, Fangling Wang, Zejun Wang   +4 more
wiley   +1 more source

Case Report: Cytoreductive nephrectomy and thrombectomy in metastatic renal cell carcinoma with venous tumor thrombus: a case using indocyanine green fluorescence-guided laparoscopy. [PDF]

Front Oncol
Dong X, Zhang J, Pan Y, Xie T, Wang J.
europepmc   +1 more source

Unveiling the complexity of cellular senescence in cancers: From mechanism to therapeutic opportunities

BMEMat, EarlyView.
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan, Ye Zhu, Zhi Ye, Huayang Zhang, Junxi Wang, Guozhong Yi, Zhiyong Li, Rongyang Xu, Luyao Wang, Zhenzhen Wu, Songtao Qi, Guanglong Huang, Shanqiang Qu   +12 more
wiley   +1 more source

The accessory renal arteries: A systematic review with meta‐analysis

Clinical Anatomy, EarlyView.
Abstract The accessory renal arteries (ARAs) are a well‐described variant of the renal vasculature with clinical implications for radiologists, surgeons, and clinicians. The aim of the present systematic review with meta‐analysis was to estimate the pooled prevalence of ARAs, including their variant number, origin, and termination, and to highlight ...
George Triantafyllou, Ioannis Paschopoulos, Andrzej Węgiel, Łukasz Olewnik, George Tsakotos, Nicol Zielinska, Maria Piagkou   +6 more
wiley   +1 more source

A comparison of effectiveness of the contrast enhanced computed tomography with magnetic resonance imaging in the differential diagnosis of clear cell renal carcinoma. [PDF]

Radiol Oncol
Blachura T, Radzikowska J, Matusik PS, Kowal A, Jarczewski JD, Skiba Ł, Popiela TJ, Chrzan R.   +7 more
europepmc   +1 more source