Results 241 to 250 of about 425,528 (280)

Targeting SPHK1 in macrophages remodels the tumor microenvironment and enhances anti‐PD‐1 immunotherapy efficacy in colorectal cancer liver metastasis

Cancer Communications, EarlyView.
Abstract Background Colorectal cancer liver metastasis (CRLM) is characterized by an immunosuppressive microenvironment and a blunted response to immunotherapy. Notably, tumor‐associated macrophages (TAMs) play a critical role in modulating immune responses and exhibit significant heterogeneity in CRLM.
Yizhi Zhan, Jinsong Xu, Zhanqiao Zhang, Yating Hu, Yongsheng Li, Junying Qian, Yunyan Ling, Dehua Wu, Haijun Deng, Guoxin Li, Zhiyong Shen, Yuan Fang   +11 more
wiley   +1 more source

Resolution of hypokalemia following nephrectomy for a presumed renal cell carcinoma revealing a large angiomyolipoma: A case report. [PDF]

Urol Case Rep
Khajeh F, Zeighami S, Ariafar A, Bazargani Z, Hakimelahi H.   +4 more
europepmc   +1 more source

Short‐chain acyl post‐translational modifications in cancers: Mechanisms, roles, and therapeutic implications

Cancer Communications, EarlyView.
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu, Yingqi Zhao, Xin Zhang, Yuanhe Wang, Qiuchen Chen, Mingrong Zhang, Huan Sheng, Yuying Zhang, Jinyu Guo, Jun Li, Yuxuan Fan, Ziqing Wang, Yalun Li, Haoran Wang, Minjie Wei, Xiaoyun Hu, Huizhe Wu   +16 more
wiley   +1 more source

Deletion of epithelial HKDC1 decelerates cellular proliferation and impairs mitochondrial function of tumorous epithelial cells thereby protecting from intestinal carcinogenesis

Cancer Communications, EarlyView.
Lea Järke, Saskia Weber‐Stiehl, Kensuke Shima, Karlis Arturs Moors, Jerome Genth, Fenja Amrei Schuran, Lena Best, Markus Tschurtschenthaler, Burkhardt Flemer, Silke Lüschen, Christoph Röcken, Andreas Tholey, Christoph Kaleta, Jan Rupp, Philip Rosenstiel, Felix Sommer   +15 more
wiley   +1 more source

Stereotactic body radiotherapy plus cadonilimab (PD‐1/CTLA‐4 bispecific antibody) as third‐line or beyond therapy for refractory solid tumors: A phase 1b study

Cancer Communications, EarlyView.
Abstract Background Cadonilimab is a humanized immunoglobulin G1 bispecific antibody targeting programmed cell death protein 1 (PD‐1) and cytotoxic T‐lymphocyte‐associated antigen 4 (CTLA‐4). This study aimed to evaluate the safety and efficacy of stereotactic body radiotherapy (SBRT) combined with cadonilimab in patients with advanced recurrent or ...
Yao Xiao, Yuxia Wang, Jun Li, Cheng Cheng, Chunyong Song, Xin Wang, Liyuan Tao, Hongqing Zhuang   +7 more
wiley   +1 more source

Metabolomic Understanding of variable risk factors for kidney cancer: a two-sample Mendelian randomization study. [PDF]

Discov Oncol
Zhu Y, Wang K, Yu Y, Li X, Zhai Y, Chen C, Li Y, Wang M, Chen D, Xing N, Yang F, Ye X.   +11 more
europepmc   +1 more source

Proliferation Cinetics and Prognosis of Renal Cell Carcinoma [PDF]

, 1991
Allhoff, E. P., Azpodien, J., Kirchner, H., Riese, W. de, Stief, Christian Georg, Werner, M.   +5 more
core  

Synchronous Bladder Metastasis From Chromophobe Renal Cell Carcinoma: A Report of a Rare Case. [PDF]

Cureus
Romero Uribe JL, Cornejo Davila V, Cruz Ruiz J.   +2 more
europepmc   +1 more source

Immune Checkpoint Inhibitor-Induced Myositis, Myocarditis, and Myasthenia Gravis Overlap Syndrome Following Nivolumab and Ipilimumab Combination Therapy in a 60-Year-Old Male With Metastatic Renal Cell Carcinoma. [PDF]

Cureus
Ismail U.
europepmc   +1 more source

Clinical and pathological analysis of primary well-differentiated neuroendocrine tumors in the kidney- a case series. [PDF]

BMC Urol
Yuan D, Wu J, Wang DY, Wang JJ.
europepmc   +1 more source