Fibroblasts in head neck squamous cell carcinoma associated with perineural invasion have high level nuclear Yes-Associated Protein (YAP) expression [PDF]
Paul A. Reynolds, PhD, is supported by the Melville Trust for the Care and cure of Cancer.We retrospectively studied the expression of Yes-associated protein (YAP) using immunohistochemical staining in 10 cases of head and neck squamous cell carcinoma ...
Gersten, Adam+5 more
core +1 more source
Beyond Squamous Cell Carcinoma: Basaloid Squamous Cell Carcinoma of the Esophagus [PDF]
Basaloid squamous cell carcinoma (BSCC) is a poorly differentiated variant of squamous cell carcinoma (SCC) with distinct morphologic characteristics. Yet, there are no clearly defined guidelines established for management. BSCC in the esophagus is a very rare entity, with the proportion of esophageal BSCC ranging from 0.068% to 11%. This wide range is
Loc Ton+4 more
openaire +2 more sources
Squamous-cell carcinoma in situ [PDF]
We present a 30-year-old woman with atopic dermatitis and ichthyosis vulgaris and a one-year history of an erythematous, scaly plaque on the dorsal surface of her right hand, which developed three years after an accidental exposure to prolonged ultraviolet C (UVC) radiation in a laboratory accident. The plaque, which was initially treated as eczematous
Rothman, Lisa R+3 more
openaire +5 more sources
Does Notch play a tumor suppressor role across diverse squamous cell carcinomas? [PDF]
The role of Notch pathway in tumorigenesis is highly variable. It can be tumor suppressive or pro-oncogenic, typically depending on the cellular context.
Biswas, Sangita+5 more
core +1 more source
The immunohistochemical expression of leptin in lymph node metastasis from laryngeal squamous cell carcinoma (SCC) [PDF]
Introduction: Leptin is a proteohormone produced predominantly by white adipocytes and primarily known for its key role in the control of food intake and sense of satiety.
D'Alessi S+7 more
core +1 more source
Squamous cell carcinoma of the breast [PDF]
Patient: Female, 60 Final Diagnosis: Primary squamosus cell carcinoma of the breast Symptoms: - Medication: - Clinical Procedure: Mastectomy Specialty: Oncology. Rare disease. Primary squamous cell carcinoma (SCC) is a very rare malignancy of the breast. It is a tumour of the elderly age group.
Sunil V Jagtap+4 more
openaire +3 more sources
Evidence-Based Treatment Options in Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck. [PDF]
The major development of the past decade in the first-line treatment of recurrent and/or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN) was the introduction of cetuximab in combination with platinum plus 5-fluorouracil chemotherapy ...
Ana Ferreira Castro+7 more
core +3 more sources
Actinic keratosis and cutaneous squamous cell carcinoma in situ are precancerous forms of cutaneous squamous cell carcinoma. In this single-centre retrospective study, patients with histopathologically confirmed actinic keratosis (n = 121) or cutaneous ...
Jaakko S. Knuutila+6 more
doaj +1 more source
Objective To investigate the expression of miR-1246 in the serum of patients with cervical squamous cell carcinoma, and to analyze the value of diagnosis, postoperative recovery and recurrence monitoring in the treatment of cervical squamous cell ...
FENG Yiming+6 more
doaj +1 more source
The retinoblastoma protein/p16INK4A pathway but not p53 is disrupted by human papillomavirus in penile squamous cell carcinoma [PDF]
Aims: The pathogenesis of penile squamous cell carcinoma (PSCC) is not well understood. Human papillomavirus (HPV) may be involved in carcinogenesis, but few studies have compared cell-cycle protein expression in HPV positive and negative cancers.
Backes+38 more
core +3 more sources