Results 51 to 60 of about 592,832 (315)

Expression of heparanase in basal cell carcinoma and squamous cell carcinoma [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2016
: Background: Heparanase is an enzyme that cleaves heparan sulfate chains. Oligosaccharides generated by heparanase induce tumor progression. Basal cell carcinoma and squamous cell carcinoma comprise types of nonmelanoma skin cancer.
Maria Aparecida Silva Pinhal   +5 more
doaj   +1 more source

Detection of HPV in cancerous and non-cancerous esophageal tissues from Turkmen-Sahra, Iran [PDF]

open access: yes, 2006
The aim of this study were to assess the presence of HPV esophageal infection among Iranian Turkmen who live in an area located in the cancer belt in Asia. The specimens derived from 120 patients previously diagnosed for Squamous Cell Carcinoma (SCC) non-
Mokhtari-Azad, T., Moradi, A.
core   +1 more source

Targeted PI3K/AKT/mTOR therapy for metastatic carcinomas of the cervix: A phase I clinical experience. [PDF]

open access: yes, 2014
BackgroundActivated PI3K/AKT/mTOR pathway frequently occurs in metastatic or recurrent cervical carcinomas. However, the clinical benefits of matched therapy, a therapeutic approach targeting a specific mutational abnormality, have not yet been ...
Coleman, Robert L   +11 more
core   +3 more sources

The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer. [PDF]

open access: yes, 2016
A better understanding of the dynamics of molecular changes occurring during the early stages of oral tumorigenesis may help refine prevention and treatment strategies.
Bertolus, Chloé   +14 more
core   +1 more source

Cancer stem cell markers in patterning differentiation and in prognosis of oral squamous cell carcinoma

open access: yesTumor Biology, 2017
Differentiation is a major histological parameter determining tumor aggressiveness and prognosis of the patient; cancer stem cells with their slow dividing and undifferentiated nature might be one of the factors determining the same.
Simple Mohanta   +8 more
doaj   +1 more source

Superficially invasive cervical squamous cell carcinoma metastatic to ovarian endometriotic cyst wall, a case report and brief review of the literature

open access: yesJournal of Ovarian Research, 2018
Background Although cases of cervical squamous cell carcinoma metastatic to the ovary have been previously documented, we report the first case of superficially invasive squamous cell carcinoma metastatic to the ovary.
Minfen Zhang   +6 more
doaj   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Angiogenesis in the progression of cutaneous squamous cell carcinoma: an immunohistochemical study of endothelial markers

open access: yesClinics, 2011
OBJECTIVE: To demonstrate the role of angiogenesis in the progression of cutaneous squamous cell carcinoma. INTRODUCTION: Angiogenesis is a pivotal phenomenon in carcinogenesis.
Michelle Etienne Baptistella Florence   +5 more
doaj   +1 more source

Treatment utilization and outcomes in elderly patients with locally advanced esophageal carcinoma: A review of the National Cancer Database [PDF]

open access: yes, 2017
For elderly patients with locally advanced esophageal cancer, therapeutic approaches and outcomes in a modern cohort are not well characterized. Patients ≥70 years old with clinical stage II and III esophageal cancer diagnosed between 1998 and 2012 were ...
Bradley, Jeffrey D   +10 more
core   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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