Results 71 to 80 of about 1,238,265 (360)

Ovarian squamous cell carcinoma

Journal of Cancer Research and Therapeutics, 2022
Ovarian squamous cell carcinoma is a rare and aggressive ovarian neoplasm, where most of the cases arise from mature teratoma, which represents up to 20% of all ovarian tumors. Moreover, primary squamous cell carcinoma is considered to be related to human papillomavirus infection.
Paulina Reyes, Tobar, Roberto Altamirano, Assad, Omar Nazzal, Nazal, Eugenio R, Suárez   +3 more
openaire   +2 more sources

Fibroblasts in head neck squamous cell carcinoma associated with perineural invasion have high level nuclear Yes-Associated Protein (YAP) expression [PDF]

, 2015
Paul A. Reynolds, PhD, is supported by the Melville Trust for the Care and cure of Cancer.We retrospectively studied the expression of Yes-associated protein (YAP) using immunohistochemical staining in 10 cases of head and neck squamous cell carcinoma ...
Gersten, Adam, Prystowsky, Michael, Wang, Yanghua, Moleirinho, Susana, Gunn-Moore, Frank, Reynolds, Paul Andrew   +5 more
core   +1 more source

Superficially invasive cervical squamous cell carcinoma metastatic to ovarian endometriotic cyst wall, a case report and brief review of the literature

Journal of Ovarian Research, 2018
Background Although cases of cervical squamous cell carcinoma metastatic to the ovary have been previously documented, we report the first case of superficially invasive squamous cell carcinoma metastatic to the ovary.
Minfen Zhang, Elena Lucas, Hanzhen Xiong, Shaoyan Liu, Kyle Molberg, Qingping Jiang, Wenxin Zheng   +6 more
doaj   +1 more source

Incomplete Excision of Cutaneous Squamous Cell Carcinoma; Systematic Review of the Literature

Acta Dermato-Venereologica, 2020
The treatment of choice for cutaneous squamous cell carcinoma is complete surgical excision. Incomplete excision of cutaneous squamous cell carcinoma has an increased risk of local recurrence, deep subclinical progression, and metastasis.
Roel E. Genders, Nick Marsidi, Marlies Michi, Erik P. Henny, Jelle J. Goeman, Marloes S. van Kester   +5 more
doaj   +1 more source

The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

Science, 2011
The mutational profile of head and neck cancer is complex and may pose challenges to the development of targeted therapies. Head and neck squamous cell carcinoma (HNSCC) is a common, morbid, and frequently lethal malignancy.
Nicolas Stransky, A. Egloff, Aaron D. Tward, Aleksandar D. Kostic, K. Cibulskis, A. Sivachenko, G. Kryukov, M. Lawrence, C. Sougnez, A. McKenna, Erica Shefler, A. Ramos, P. Stojanov, S. Carter, D. Voet, M. Cortés, Daniel Auclair, Michael F. Berger, G. Saksena, C. Guiducci, R. Onofrio, Melissa Parkin, M. Romkes, J. Weissfeld, Raja R. Seethala, Lin Wang, C. Rangel-Escareño, J. Fernández-López, A. Hidalgo-Miranda, J. Meléndez-Zajgla, W. Winckler, K. Ardlie, S. Gabriel, M. Meyerson, Eric S. Lander, G. Getz, T. Golub, Levi A. Garraway, J. Grandis   +38 more
semanticscholar   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Carrier cell-mediated cell lysis of squamous cell carcinoma by squamous cell carcinoma antigen 1 promoter-driven oncolytic adenovirus [PDF]

, 2009
The squamous cell carcinoma antigen (SCCA) serves as a serological marker for squamous cell carcinomas. Molecular cloning of the SCCA genomic region has revealed the presence of two tandemly arrayed genes, SCCA1 and SCCA2.
Yoshiyuki Koyama, Hiroyuki Hamakawa, Hiroshi Ito, Kenzaburo Tani, Junzo Desaki, Ting Zhang, Katsuyuki Hamada, Koh-ichi Nakashiro   +7 more
core   +1 more source

PD‐1 Blockade with Cemiplimab in Advanced Cutaneous Squamous‐Cell Carcinoma

New England Journal of Medicine, 2018
Background No systemic therapies have been approved for the treatment of advanced cutaneous squamous‐cell carcinoma. This cancer may be responsive to immune therapy, because the mutation burden of the tumor is high and the disease risk is strongly ...
M. Migden, D. Rischin, C. Schmults, A. Guminski, A. Hauschild, K. Lewis, C. Chung, L. Hernandez-Aya, A. Lim, A. Chang, G. Rabinowits, A. Thai, L. Dunn, B. Hughes, N. Khushalani, B. Modi, D. Schadendorf, Bo Gao, F. Seebach, Siyu Li, Jingjin Li, M. Mathias, J. Booth, K. Mohan, E. Stankevich, H. Babiker, I. Braña, M. Gil-Martin, J. Homsi, M. Johnson, V. Moreno, J. Niu, T. Owonikoko, K. Papadopoulos, G. Yancopoulos, I. Lowy, M. Fury   +36 more
semanticscholar   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Surgical management of oral squamous cell carcinoma infiltrating mandible [PDF]

, 2008
Progression of recent trends in mandible-preserving operations for the management of oral squamous cell carcinomas that infiltrate the mandible is rapid and accompanying studies give invaluable information concerning behavioral understanding of oral ...
Kim, Hyung Jun
core