Results 41 to 50 of about 1,238,265 (360)

Dissecting esophageal squamous-cell carcinoma ecosystem by single-cell transcriptomic analysis

Nature Communications, 2021
Esophageal squamous-cell carcinoma (ESCC), one of the most prevalent and lethal malignant disease, has a complex but unknown tumor ecosystem. Here, we investigate the composition of ESCC tumors based on 208,659 single-cell transcriptomes derived from 60 ...
Xiannian Zhang, Linna Peng, Yingying Luo, Shaosen Zhang, Yang Pu, Yamei Chen, Wenjia Guo, Jiacheng Yao, Mingming Shao, W. Fan, Qionghua Cui, Yiyi Xi, Yanxia Sun, Xia Niu, Xuan Zhao, Liping Chen, Yuqian Wang, Yachen Liu, Xinyu Yang, Chengcheng Wang, Ce-jun Zhong, W. Tan, Jianbin Wang, Chen Wu, D. Lin   +24 more
semanticscholar   +1 more source

Application of Pathological Staging in Esophageal Squamous Cell Carcinoma [PDF]

, 2020
Pathological staging is the most important factor that determines the prognosis and management of patients with esophageal squamous cell carcinoma. The method for the pathological staging in esophageal squamous cell carcinoma involves assessment of ...
Lam, AK, Alfred K. Lam
core   +1 more source

Integrative analysis of lysine acetylation-related genes and identification of a novel prognostic model for oral squamous cell carcinoma

Frontiers in Molecular Biosciences, 2023
Introduction: Oral squamous cell carcinoma (OSCC), which accounts for a high proportion of oral cancers, is characterized by high aggressiveness and rising incidence. Lysine acetylation is associated with cancer pathogenesis.
Shi-Zhou Deng, Xuechen Wu, Jiezhang Tang, Lin Dai, Bo Cheng   +4 more
doaj   +1 more source

B cell signatures and tertiary lymphoid structures contribute to outcome in head and neck squamous cell carcinoma

Nature Communications, 2021
Current immunotherapy paradigms aim to reinvigorate CD8+ T cells, but the contribution of humoral immunity to antitumor immunity remains understudied.
A. Ruffin, A. Cillo, T. Tabib, Angen Liu, Sayali S Onkar, S. Kunning, C. Lampenfeld, Huda I Atiya, I. Abécassis, Cornelius H. L. Kürten, Z. Qi, R. Soose, U. Duvvuri, Seungwon Kim, Steffi Oesterrich, R. Lafyatis, L. Coffman, R. Ferris, D. Vignali, T. Bruno   +19 more
semanticscholar   +1 more source

Technical and clinical performance of a new assay to detect squamous cell carcinoma antigen levels for the differential diagnosis of cervical, lung, and head and neck cancer

Tumor Biology, 2018
In squamous cell carcinoma, squamous cell carcinoma antigen levels are often elevated. This multi-center study evaluated the technical performance of a new Elecsys ® squamous cell carcinoma assay, which measures serum squamous cell carcinoma antigen 1 ...
Stefan Holdenrieder, Rafael Molina, Ling Qiu, Xiuyi Zhi, Sandra Rutz, Christine Engel, Pia Kasper-Sauer, Farshid Dayyani, Catharina M Korse   +8 more
doaj   +1 more source

High-grade tumor budding is a risk factor for survival in patients with laryngeal squamous cell carcinoma

Brazilian Journal of Otorhinolaryngology, 2023
Objective: With the increasing incidence and mortality of laryngeal squamous cell carcinoma worldwide, researchers continue to search for novel prognostic factors and treatment methods for preventing early laryngeal squamous cell carcinoma from becoming ...
Li Luo, Honggang Liu
doaj   +1 more source

Preliminary evaluation for Bit1 as a potential biomarker for squamous cell carcinoma and adenocarcinoma of esophagus

Tumor Biology, 2017
Mounting evidence has demonstrated that Bit1 has been investigated as an etiological factor for certain cancers, including esophageal squamous cell carcinoma reported in our previous study, but data regarding possible roles of Bit1 in esophageal squamous
Jing Chen, Hongtao Liu, Pan Gao, Yiran Hui, Zhenzhen Yang, Xiaqing Zhang, Peirong Xu, Fang Tian, Tianli Fan   +8 more
doaj   +1 more source

E47 upregulates ΔNp63α to promote growth of squamous cell carcinoma

Cell Death and Disease, 2021
Targeted therapy has greatly improved both survival and prognosis of cancer patients. However, while therapeutic treatment of adenocarcinoma has been advanced greatly, progress in treatment of squamous cell carcinoma (SCC) has been slow and ineffective ...
Jing Xu, Fengtian Li, Ya Gao, Rongtian Guo, Liangping Ding, Mengyuan Fu, Yong Yi, Hu Chen, Zhi-Xiong Jim Xiao, Mengmeng Niu   +9 more
doaj   +1 more source

Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck

New England Journal of Medicine, 2016
BACKGROUND Patients with recurrent or metastatic squamous-cell carcinoma of the head and neck after platinum chemotherapy have a very poor prognosis and limited therapeutic options.
R. Ferris, G. Blumenschein, J. Fayette, J. Guigay, A. Colevas, L. Licitra, K. Harrington, S. Kasper, E. Vokes, C. Even, F. Worden, N. Saba, L. Iglesias Docampo, R. Haddad, T. Rordorf, N. Kiyota, M. Tahara, M. Monga, M. Lynch, W. Geese, J. Kopit, J. Shaw, M. Gillison   +22 more
semanticscholar   +1 more source

Risk factors for adenocarcinoma and squamous cell carcinoma of the cervix in women aged 20-44 years: the UK National Case-Control Study of Cervical Cancer. [PDF]

, 2003
We report results on risk factors for invasive squamous cell and adenocarcinomas of the cervix in women aged 20-44 years from the UK National Case-Control Study of Cervical Cancer, including 180 women with adenocarcinoma, 391 women with squamous cell ...
Mant, David, Chilvers, C, Green, Jane, P Jha, Green, J, C Chilvers, Sweetland, S, J Peto, Deacon, J, J Green, A Berrington de Gonzalez, Hermon, C, V Beral, Jha, P, S Sweetland, J Deacon, Mant, D, C Hermon, D Mant, Peto, J, M Pike, Vessey, MP, Sweetland, Sian, Crossley, B, M P Vessey, Pike, M, B Crossley, Beral, Valerie, Beral, V, Berrington de Gonzalez, A   +29 more
core   +1 more source