Results 31 to 40 of about 3,245,969 (343)

Increased Angiogenin Expression Correlates With Radiation Resistance and Predicts Poor Survival for Patients With Nasopharyngeal Carcinoma

open access: yesFrontiers in Pharmacology, 2021
Background: Despite the development of such multiple therapeutic approaches, approximately 20% patients experience recurrence. Identification of molecular markers for stratifying the different risks of tumour recurrence and progression is considered ...
Shan-Shan Guo   +22 more
doaj   +1 more source

Spatial heterogeneity of immune infiltration predicts the prognosis of nasopharyngeal carcinoma patients

open access: yesOncoImmunology, 2021
Spatial information on the tumor immune microenvironment is of clinical relevance. Here, we aimed to quantify the spatial heterogeneity of lymphocytes and cancer cells and evaluated its prognostic value in patients with nasopharyngeal carcinoma (NPC ...
Ya-Qin Wang   +14 more
doaj   +1 more source

Management of hepatocellular carcinoma: An update

open access: yesHepatology, 2011
Since the publication of the American Association for the Study of Liver Diseases (AASLD) practice guidelines on the management of hepatocellular carcinoma (HCC) in 2005, new information has emerged that requires that the guidelines be updated.
J. Bruix, M. Sherman
semanticscholar   +1 more source

Integrated genomic characterization of endometrial carcinoma

open access: yesNature, 2013
We performed an integrated genomic, transcriptomic and proteomic characterization of 373 endometrial carcinomas using array- and sequencing-based technologies.
Douglas A. Levine   +273 more
semanticscholar   +1 more source

Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck.

open access: yesNew England Journal of Medicine, 2016
BACKGROUND Patients with recurrent or metastatic squamous-cell carcinoma of the head and neck after platinum chemotherapy have a very poor prognosis and limited therapeutic options.
Robert L Ferris   +22 more
semanticscholar   +2 more sources

The CXCL5/CXCR2 axis contributes to the epithelial-mesenchymal transition of nasopharyngeal carcinoma cells by activating ERK/GSK-3β/snail signalling

open access: yesJournal of Experimental & Clinical Cancer Research, 2018
Background Distant metastasis is the major cause of treatment failure in patients with nasopharyngeal carcinoma (NPC). Although several biomarkers correlate with metastasis and prognosis, the molecular mechanisms of NPC development and progression remain
Wen-Ze Qiu   +13 more
doaj   +1 more source

Norcantharidin induces G2/M arrest and apoptosis via activation of ERK and JNK, but not p38 signaling in human renal cell carcinoma ACHN cells

open access: yesActa Pharmaceutica, 2021
Renal cell carcinoma (RCC) is generally acknowledged as the most resistant primary malignancy unresponsive to conventional radiotherapy and chemotherapy treatments.
Huang Shuaishuai   +5 more
doaj   +1 more source

Adding Concurrent Chemotherapy Significantly Improves the Survival of Stage II-IVb Nasopharyngeal Carcinoma Patients Treated With Concurrent Anti-EGFR Agents

open access: yesFrontiers in Oncology, 2021
ObjectiveAnti-EGFR Targeted agents were found to be capable of modulating the antitumor immunity in head and neck cancer and become more and more frequently used in the treatment of nasopharyngeal carcinoma(NPC).
Zi-Kun Yu   +11 more
doaj   +1 more source

Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck.

open access: yesNew England Journal of Medicine, 2006
BACKGROUND We conducted a multinational, randomized study to compare radiotherapy alone with radiotherapy plus cetuximab, a monoclonal antibody against the epidermal growth factor receptor, in the treatment of locoregionally advanced squamous-cell ...
J. Bonner   +17 more
semanticscholar   +1 more source

Limited recurrence distance of glioblastoma under modern radiotherapy era

open access: yesBMC Cancer, 2021
Background The optimal treatment volume for Glioblastoma multiforme (GBM) is still a subject of debate worldwide. The current study was aimed to determine the distances between recurring tumors and the edge of primary lesions, and thereby provide ...
Ziwei Tu   +5 more
doaj   +1 more source

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