Results 41 to 50 of about 3,612,501 (345)

Harnessing Machine Learning and Nomogram Models to Aid in Predicting Progression-Free Survival for Gastric Cancer Patients Post-Gastrectomy with Deficient Mismatch Repair(dMMR)

BMC Cancer
Objective To assess the effectiveness of a machine learning framework and nomogram in predicting progression-free survival (PFS) post-radical gastrectomy in patients with dMMR.
Yifan Li, JinFeng Ma, Wenhua Cheng
doaj   +1 more source

CARCINOMA OF THE BREAST

Annals of Surgery, 1934
Abstract 1. 1. The histological grading of malignancies is not as generally accepted by pathologists as it is by surgeons. 2. 2. There are too many factors to be considered in such a grading to give any uniform opinion. 3. 3. Postoperative irradiation presents another disturbing factor in estimating any histological index. 4. 4.
openaire   +5 more sources

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

Screening high-risk individuals for primary gastric carcinoma: evaluating overall survival probability score in the presence and absence of lymphatic metastasis post-gastrectomy

World Journal of Surgical Oncology
Objective The aim of this study was to develop and validate prognostic models for predicting overall survival in individuals with gastric carcinoma, specifically focusing on both negative and positive lymphatic metastasis.
Wenqing Qu, Ling Li, Jinfeng Ma, Yifan Li   +3 more
doaj   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Primary Transitional Cell Carcinoma of the Fallopian Tube [PDF]

, 2012
Primary carcinoma of the fallopian tube is a rare entity that accounts for 0.2-0.5% of all gynecologic malignancies, and most are discovered during or after surgery.
Kaushal, V, Mardi, K
core   +1 more source

Harnessing the machine learning and nomogram models: elevating prognostication in nonmetastatic gastric cancer with “double invasion” for personalized patient care

European Journal of Medical Research
Objective To develop and validate a machine learning framework combined with a nomogram for predicting recurrence after radical gastrectomy in patients with vascular and neural invasion.
Zhenwen Hao, Zhiming Wang, Jinfeng Ma, Yifan Li, Wenbin Zhang   +4 more
doaj   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Metaplastic Carcinoma of the Left Breast with Extensive Chondroid Differentiation [PDF]

, 2011
Metaplastic breast carcinoma is very rare neoplasm which contains mixture of carcinomatous (epithelial) and sarcomatous (mesenchymal) elements in variable proportion. Metaplastic carcinoma with chondroid differentiation is even rarer.
Bohra, Ashish, Jagtap, Sunil V, Jain, Gaurav, Kanetkar, Sujata R, Nikumbh, Dhiraj B   +4 more
core   +1 more source

The shifting nature of women’s experiences and perceptions of ductal carcinoma in situ [PDF]

, 2011
Aim: This paper is a report of a descriptive qualitative study of the evolution of women’s perceptions and experiences of ductal carcinoma in situ from the period near to diagnosis to one year later.
Baum, Braun, Buick, Buick, Cady, Cameron, Carrera, Carrera, De Morgan, De Morgan, Dell, Erbas, Ernster, Evans, Fallowfield, Farmer, Fereday, Flick, Ganz, Godby, Goldsmith, Graff, Houghton, Janz, Kelly, Kennedy, Kennedy, Kennedy, Kennedy, Lauzier, Leonard, Leventhal, Leventhal, Mittra, Morrow, Napoles-Springer, Nekhlyudov, NHSBSP, NHSBSP, Oliffe, Partridge, Partridge, Prinjha, Rakovitch, Schmid-Buchi, Smith, Streubert, Teddlie, Ward, Webb, Wong, Ziebland   +51 more
core   +1 more source