Results 101 to 110 of about 220,392 (312)

Evaluation of expression of p16INK4a & Survivin in squamous neoplasm of cervix- A 3 years study [PDF]

open access: yesPerspectives In Medical Research, 2017
Objective: To explore the expression of p16INK4a(p16) & survivin in cervical intraepithelial neoplasm (CIN) & cervical squamous neoplasm. Materials & Methods: A 3years study was undertaken in MGM Hospital, Warangal, all the cervical & hysterectomy ...
S. Lokesh Rao Magar1 , G.Vandana2 , Sobha Devi3 , H.Sandhya Rani4 , Sandhya Anil5
doaj  

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang   +9 more
wiley   +1 more source

Fluorescencein situhybridization and qPCR to detect Merkel cell polyomavirus physical status and load in Merkel cell carcinomas [PDF]

open access: hybrid, 2014
Anke Haugg   +6 more
openalex   +1 more source

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin   +16 more
wiley   +1 more source

Reprogramming Antitumor Immunity: NK Cell Strategies to Navigate the Immunosuppressive Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
ABSTRACT Tumor immune escape is a major barrier to durable cancer immunotherapy, as advanced malignancies create a tumor microenvironment (TME) that preferentially exhausts and disables T cell responses. While most approved cell therapies are T cell‐based, this limitation motivates the exploration of an alternative effector cell platform.
Tereza Kochs   +4 more
wiley   +1 more source

A rare case of male breast ductal carcinoma in-situ associated with prolactinoma [PDF]

open access: bronze, 2011
Chandike M. Mallawaarachchi   +4 more
openalex   +1 more source

Carcinoma in situ: revisão

open access: yesClinical and Biomedical Research, 2017
O carcinoma ductal in situ (CDIS) compreende um grupo de lesões biologicamente e morfologicamente heterogêneo. A sua incidência vem crescendo principalmente devido aos programas de rastreamento por mamografia, o que contribuiu para o aumento do seu diagnóstico entre pacientes assintomáticas. O achado mais freqüente é de microcalcificações.
Biazús, Jorge Villanova   +1 more
openaire   +2 more sources

SpaMode: A Broadly Applicable Framework for Deciphering Spatial Multi‐Omics Using Multimodal Mixture of Disentangled Experts

open access: yesAdvanced Science, EarlyView.
SpaMode introduces a versatile framework for spatial multi‐omics integration across vertical, horizontal, and mosaic scenarios. By disentangling modality‐invariant and variant features through a mixture‐of‐experts mechanism, it adaptively reconfigures spatially heterogeneous signals.
Xubin Zheng   +6 more
wiley   +1 more source

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