Results 81 to 90 of about 114,360,625 (248)
Pakistan Armed Forces Medical Journal, 2020 Objective: To determine the prevalence of histological subtypes of breast cancer and its association with age, molecular subtype, menopausal status, parity, obesity and tumor grade. Study Design: Prospective, observational study. Place and Duration
Shumyla Beg +7 more
doaj
Potential biomarkers of ductal carcinoma in situ progression
BMC Cancer, 2020 Background Ductal carcinoma in situ is a non-obligate precursor of invasive breast carcinoma and presents a potential risk of over or undertreatment. Finding molecular biomarkers of disease progression could allow for more adequate patient treatment.
Raquel Spinassé Dettogni +17 more
doaj +1 more source
Advanced Science, EarlyView.Single‐cell mechanomics demonstrates that pharmacological perturbation changes cytoskeletal and cortical structure, suppressing cancer cell invasiveness. By integrating atomic force microscopy (AFM)‐based cortical measurements with stimulated emission depletion (STED)‐resolved adhesion and cytoskeletal organization, this approach identifies nanoscale ...
Minhee Ku +4 more
wiley +1 more source
Serum microRNA-21 as marker for necroinflammation in hepatitis C patients with and without hepatocellular carcinoma [PDF]
, 2011 Background: MicroRNA-21 (miR-21) is up-regulated in tumor tissue of patients with malignant diseases, including hepatocellular carcinoma (HCC). Elevated concentrations of miR-21 have also been found in sera or plasma from patients with malignancies ...
Polta, Andreas +55 more
core +2 more sources
Advanced Science, EarlyView.ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu +10 more
wiley +1 more source
Trichilemmal Carcinoma in situ [PDF]
, 1991 We report one case of trichilemmal carcinoma in situ of hair follicle origin in a 79-year-old female in this paper. This tumor was histopathologically diagnosed as carcinoma in situ and extended from the infundibulum to the isthmus of the hair follicle.
Hidenari KUSAKABE +3 more
core +1 more source
Advanced Science, EarlyView.An in situ‐grown BP‐CaO2 nanoplatform supplies coordinated Ca2+, endogenous phosphate, and oxidative stress to convert tumor calcification from a passive endpoint into an active immune‐remodeling process. Widespread hydroxyapatite deposition is visualized by CT, while multi‐omics reveals MCOLN2 as a calcium‐responsive mediator linking biomineralization
Long Liu +11 more
wiley +1 more source
Rewiring Pyroptosis to Potentiate Cancer Immunotherapy via a Gasdermin D Agonist Bypassing Caspase‐3
Advanced Science, EarlyView.This work introduces a small‐molecule agonist, DIBDO, that bypasses Casp‐3 to directly trigger GSDMD‐mediated pyroptosis in tumors. Activated by glutathione, DIBDO generates singlet oxygen and molecular iodine, blocking Casp‐3 pathways and inducing immunogenic cell death.
Dan Zhao +6 more
wiley +1 more source
Zhongguo aizheng zazhi, 2013 Background and purpose: Encapsulated papillary carcinoma (EPC) of the breast is a kind of rare malignant tumor, which is difficult to diagnose before surgery.
丁锦华, 吴伟主, 甘咏莉
doaj
Diagnosis of Extensive DCIS with Progressive Microcalcifications over a Period of 11 Years
DiagnosticsA 53-year-old woman presented complaining of enlargement of her right breast; 12 years earlier she was treated elsewhere for an invasive ductal carcinoma of the right breast with breast-conserving surgery, adjuvant chemotherapy, anti-HER2 therapy ...
Menelaos Zafrakas +3 more
doaj +1 more source