Results 71 to 80 of about 114,360,625 (248)

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Different distribution of breast cancer subtypes in breast ductal carcinoma in situ and ductal carcinoma in situ with microinvasion

Zhongguo aizheng zazhi, 2018
Background and purpose: Breast ductal carcinoma in situ with microinvasion (DCIS-MI) is considered to be the interim stage in the progression from breast ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC).
李　爽, 郎冠天, 余科达
doaj  

CIS of the bladder: a review of literature

Urology Research and Practice, 2019
Carcinoma in situ (CIS) of the bladder poses a clinical challenge to urologists worldwide. The clinical course of CIS ranges from benign, indolent tumor growth to highly progressive tumor proliferation with deleterious effects on patient outcome and ...
Ahmed Fouad Kotb, Mohamed Mohie Hashad, Ahmed Elabbady   +2 more
doaj   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

Expression of p53 oncoprotein in human ductal breast carcinoma (in situ, invasive and metastatic) [PDF]

, 2009
Breast cancer is a malignant tumor mostly disclosed in women. It has heterogeneous biological behavior - so that the knowledge of tumor markers is very important to determine its prognosis and therapy.
Imam Susilo, NIDN. 0010086503
core   +1 more source

Consideraciones en patología no invasiva

Revista Colombiana de Obstetricia y Ginecología, 1997
Hiperplasia epitelial y enfermedad proliferativa. Riesgo relativo de desarrollar cáncer de mama. Carcinoma in situ (estado o (tis nomo). Carcinoma lobulillar in situ (cli). Carcinoma ductal in situ (cd/s). Enfermedad de paget in situ.
Federación Colombiana de Obstetricia y Ginecologia
doaj   +1 more source

Multi‐regional Organoid Biobank Reveals FAK‐ACSL1‐Driven Doxorubicin‐Resistance and Predictive Biomarkers in Breast Cancer

Advanced Science, EarlyView.
This study established a high‐quality organoid biobank derived from 68 tumor sites across 50 Chinese patients, elucidated the drug sensitivity‐based molecular subtyping in breast cancer, and revealed a novel mechanism of drug resistance mediated by the FAK‐ACSL1 pathway.
Hao Xu, Zhijun Qin, Jiapeng Yang, Baoyuan Zhang, Manqing Cao, Peng Wang, Zaiqi Wang, Jinghui Cheng, Lei Wang, Hong Liu, Hui Yang   +10 more
wiley   +1 more source

Ductal Carcinoma in situ: Underestimation of Percutaneous Biopsy and Positivity of Sentinel Lymph Node Biopsy in a Brazilian Public Hospital

, 2021
Rafael da Silva Sá,1,2 Angela Flávia Logullo,3 Simone Elias,1 Gil Facina,1 Vanessa Monteiro Sanvido,1 Afonso Celso Pinto Nazário1 1Department of Gynaecology, Breast Surgery Team, Universidade Federal de São Paulo (UNIFESP), S ...
Facina G, Sanvido VM, Elias S, Nazário ACP, Sá RS, Logullo AF   +5 more
core  

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen, Cong Zhang, Song Xue, Yuan Zeng, Haochen Cui, Chenfei Wang, Jiayi Feng, Lei Yan, Yuanwei Zang   +8 more
wiley   +1 more source

Burgemeester van Suchtelenstraat Ex-Situ Archeologierapport 5

, 2022
Op 19 februari 2019 heeft Ex-Situ Archeologie een proefsleuvenonderzoek uitgevoerd op het perceel Burgermeester van Suchtelenstraat in de gemeente Beuningen.
Ex-Situ arch. advies en projectbureau
core   +1 more source