Results 111 to 120 of about 368,924 (355)

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu   +12 more
wiley   +1 more source

In situ carcinoma of the conjunctiva: surgical excision associated with cryotherapy

open access: yesClinical Ophthalmology, 2013
Nicolás Crim, María Elena Forniés-Paz, Rodolfo Monti, Evangelina Espósito, Juan Pablo Maccio, Julio A Urrets-Zavalía Department of Ophthalmology, University Clinic Reina Fabiola, Universidad Católica de Có ...
Crim N   +5 more
doaj  

Carcinoma in situ: revisão

open access: yesClinical and Biomedical Research, 2022
O carcinoma ductal in situ (CDIS) compreende um grupo de lesões biologicamente e morfologicamente heterogêneo. A sua incidência vem crescendo principalmente devido aos programas de rastreamento por mamografia, o que contribuiu para o aumento do seu ...
Jorge V. Biazús, Fernando Schuh
doaj  

No Ink on Ductal Carcinoma In Situ: A Single Centre Experience [PDF]

open access: bronze, 2018
Piero Fregatti   +7 more
openalex   +1 more source

Carcinoma in situ: revisão

open access: yesClinical and Biomedical Research, 2017
O carcinoma ductal in situ (CDIS) compreende um grupo de lesões biologicamente e morfologicamente heterogêneo. A sua incidência vem crescendo principalmente devido aos programas de rastreamento por mamografia, o que contribuiu para o aumento do seu diagnóstico entre pacientes assintomáticas. O achado mais freqüente é de microcalcificações.
Biazús, Jorge Villanova   +1 more
openaire   +2 more sources

TRIM38 Suppresses Breast Cancer Progression via Modulating SQSTM1 Ubiquitination and Autophagic Flux

open access: yesAdvanced Science, EarlyView.
TRIM38, an E3 ubiquitin ligase, suppresses breast cancer progression by inhibiting proliferation, migration, and invasion. Downregulated in breast tumor, its loss correlates with poor prognosis. Mechanistically, TRIM38 mediates K63‐linked ubiquitination of SQSTM1/p62 at K420, disrupting SQSTM1‐LC3 interaction and blocking autophagic flux.
Shan Jiang   +14 more
wiley   +1 more source

Evaluation of survivin immunoexpression in the differentiation of high- and low-grade breast ductal carcinoma in situ

open access: yesEinstein (São Paulo)
Objective To evaluate the expression of survivin protein in low- and high-grade ductal carcinoma in situ. Methods Breast tissue fragments obtained by incisional biopsy and surgical procedures of 37 women with ductal carcinoma in situ of the breast were ...
Milca Cezar Chade   +6 more
doaj   +1 more source

Importance of microcalcifications in mammographic differentiation of the invasive ductal breast cancer and of the ductal carcinoma in situ [PDF]

open access: yesMedicinski Podmladak, 2017
Introduction: Microcalcifications represent a significant and reliable sign of the presence of the malignant breast lesion. Aim: The aim of the paper is to radiologically evaluate the type and distribution of suspicious microcalcifications, in patients ...
Šarac Vanja, Nadrljanski Mirjan
doaj  

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

open access: yesAdvanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng   +9 more
wiley   +1 more source

Evaluation of expression of p16INK4a & Survivin in squamous neoplasm of cervix- A 3 years study [PDF]

open access: yesPerspectives In Medical Research, 2017
Objective: To explore the expression of p16INK4a(p16) & survivin in cervical intraepithelial neoplasm (CIN) & cervical squamous neoplasm. Materials & Methods: A 3years study was undertaken in MGM Hospital, Warangal, all the cervical & hysterectomy ...
S. Lokesh Rao Magar1 , G.Vandana2 , Sobha Devi3 , H.Sandhya Rani4 , Sandhya Anil5
doaj  

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