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Cardiac amyloidosis is a disease characterised by the accumulation of amyloid protein in the heart tissue. There are several types of amyloidosis, but the most common types affecting the heart are ATTR amyloidosis (caused by transthyretin protein) and ...
Natallia Laptseva +3 more
doaj +8 more sources
Nuclear Imaging for the Diagnosis of Cardiac Amyloidosis in 2021
Cardiac amyloidosis is caused by the deposition of misfolded protein fibrils into the extracellular space of the heart. The diagnosis of cardiac amyloidosis remains challenging because of the heterogeneous manifestations of the disease.
Weijia Li +2 more
exaly +3 more sources
Unraveling cardiac amyloidosis in Egypt: diagnostic challenges and disease outcomes [PDF]
Background Cardiac amyloidosis is an infiltrative cardiomyopathy caused by extracellular deposition of insoluble amyloid fibrils. Despite the growing global recognition of cardiac amyloidosis and the recent development of targeted therapeutic strategies ...
Rasha Mohamed Abayazeed +12 more
doaj +2 more sources
Survival Outcomes in Transthyretin Cardiac Amyloidosis in the Tafamidis Era: Real-World Evidence from Greece [PDF]
Background: Diagnoses of transthyretin amyloid cardiomyopathy (ATTR-CM) have increased in recent years, with a growing proportion of patients being identified at earlier disease stages.
Freideriki Eleni Kourti +16 more
doaj +2 more sources
Light Chain Cardiac Amyloidosis With Skeletal Muscle Weakness [PDF]
Background: Amyloid light chain (AL) amyloidosis can manifest with heterogeneous, multisystem features. Cardiac involvement is common and drives prognosis.
Elyn Montgomery, BN, PhD +6 more
doaj +2 more sources
Smartwatch-Detected Sinus Tachycardia Unmasking AL Cardiac Amyloidosis in a Young Adult [PDF]
Background: The clinical presentation of immunoglobulin light-chain (AL) can be very heterogenous resulting in delayed diagnosis and treatment. The use of wearable health technology is rapidly expanding.
Grace O'Dea, MB, BCh, BAO, MSc +2 more
doaj +2 more sources
Amyloid deposits are defined by their tinctorial properties. Under the light microscope amyloid deposits are eosinophilic and amorphous when stained with hematoxylin and eosin. With Congo red staining the deposits are positive and under polarized light will exhibit green birefringence.
T, Tadokoro +3 more
openaire +4 more sources
Systemic amyloidosis comprises an uncommon group of disorders caused by the extracellular deposition of misfolded proteins in various organs. Cardiac amyloid deposition, causing an infiltrative/restrictive cardiomyopathy, is a frequent feature of amyloidosis and a major determinant of survival.
Martinez-Naharro, A +2 more
openaire +6 more sources
Background. Heart transplantation in cardiac amyloidosis (CA) patients is possible and generally considered for transplantation if other organs are not affected.
Soulef Guendouz, MD +27 more
doaj +1 more source
The causal protein of amyloid light‐chain (AL) amyloidosis is a monoclonal immunoglobulin free light chain (mFLC), which must be quantified in the serum for patient diagnosis and monitoring.
Hajer Abroud +18 more
doaj +1 more source

