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Cardiac amyloidosis is an increasingly recognized cause of heart failure. It remains underdiagnosed despite a significant morbidity and mortality rate. The mean survival in patients with cardiac amyloidosis is less than 1 year in untreated primary light ...
Temidayo Abe+5 more
doaj +1 more source
Catastrophic Cardiac Amyloidosis [PDF]
We report a case of a 61-year-old patient presenting with cardiogenic shock. His echocardiogram suggested typical features of cardiac amyloidosis. This case demonstrates that cardiac amyloidosis can present acutely and may be catastrophic.
Prashanth Panduranga, Mohammed Mukhaini
openaire +4 more sources
Natural history and outcome in systemic AA amyloidosis [PDF]
BACKGROUND:Deposition of amyloid fibrils derived from circulating acute-phase reactant serum amyloid A protein (SAA) causes systemic AA amyloidosis, a serious complication of many chronic inflammatory disorders.
Gallimore, JR+6 more
core +1 more source
Aims As evidenced by scintigraphy imaging, the prevalence of transthyretin (TTR) cardiac amyloidosis in heart failure patients with preserved ejection fraction (HFpEF) and left ventricular hypertrophy (LVH) ranges between 13% and 19%.
Ana Devesa+10 more
doaj +1 more source
The frequency of cardiac involvement varies among other types of amyloidosis. Cardiac amyloidosis leads to systolic and diastolic dysfunction with symptoms of heart failure. Cardiac magnetic resonance (CMR) findings are helpful in supporting the diagnosis of amyloid cardiomyopathy.
Lu, P., Van Acker, H., Waer, P.
openaire +4 more sources
Uncovering the Mechanism of Aggregation of Human Transthyretin. [PDF]
The tetrameric thyroxine transport protein transthyretin (TTR) forms amyloid fibrils upon dissociation and monomer unfolding. The aggregation of transthyretin has been reported as the cause of the life-threatening transthyretin amyloidosis.
Cascio, Duilio+9 more
core +2 more sources
Background Precise data about ATTR-CM incidence rates at national level are scarce. Consequently, this study aimed to estimate the annual incidence and survival of transthyretin amyloid cardiomyopathy (ATTR-CM) in France between 2011 and 2019 using real ...
Thibaud Damy+21 more
doaj +1 more source
Treatment of ankylosing spondylitis and extra-articular manifestations in everyday rheumatology practice [PDF]
The SpAs are a group of overlapping, chronic, inflammatory rheumatic diseases including AS, a chronic inflammatory disease primarily affecting the SI joints.
Elewaut, Dirk, Matucci-Cerinic, Marco
core +1 more source
Diagnostic sensitivity of abdominal fat aspiration in cardiac amyloidosis [PDF]
Aims: Congo red staining of an endomyocardial biopsy is the diagnostic gold-standard in suspected cardiac amyloidosis (CA), but the procedure is associated with the risk, albeit small, of serious complications, and delay in diagnosis due to the ...
Botcher, N+15 more
core +1 more source
Amyloidosis is a systemic disorder characterized by the deposition of mis-folded protein molecules within various organs. Cardiac involvement may be the presenting feature of this condition or may be identified incidentally during investigation for ...
Anish George, Brian McClements
doaj +1 more source