Results 31 to 40 of about 1,299,020 (330)

Cardiac Amyloidosis

Heart Views, 2021
Amyloidosis represents a heterogeneous group of disorders caused by amyloid fibril deposition in the extracellular space in different organs. Among the many types of amyloidosis cardiac involvement occurs almost exclusively with immunoglobulin light chain amyloidosis (AL amyloidosis) or transthyretin amyloidosis (ATTR amyloidosis). When present cardiac
Salah Elbdri, Rachel Hajar
openaire   +6 more sources

Patisiran Treatment in Patients with Transthyretin Cardiac Amyloidosis.

New England Journal of Medicine, 2023
BACKGROUND Transthyretin amyloidosis, also called ATTR amyloidosis, is associated with accumulation of ATTR amyloid deposits in the heart and commonly manifests as progressive cardiomyopathy. Patisiran, an RNA interference therapeutic agent, inhibits the
M. S. Maurer, P. Kale, M. Fontana, J. Berk, M. Grogan, F. Gustafsson, Rebecca R Hung, R. Gottlieb, Thibaud Damy, Alejandra González-Duarte, N. Sarswat, Yoshiki Sekijima, Nobuhiro Tahara, Mark S. Taylor, M. Kubanek, E. Donal, T. Paleček, Kenichi Tsujita, W. H. W. Tang, Wen-Chung Yu, L. Obici, M. Simões, Fábio Fernandes, S. Poulsen, Igor Diemberger, F. Perfetto, S. Solomon, Marcelo F. Di Carli, Prajakta Badri, M. White, Jihong Chen, E. Yureneva, M. Sweetser, P. Jay, Pushkal P. Garg, J. Vest, J. Gillmore   +36 more
semanticscholar   +1 more source

Heart Transplantation, Either Alone or Combined With Liver and Kidney, a Viable Treatment Option for Selected Patients With Severe Cardiac Amyloidosis

Transplantation Direct, 2022
Background. Heart transplantation in cardiac amyloidosis (CA) patients is possible and generally considered for transplantation if other organs are not affected.
Soulef Guendouz, MD, Philippe Grimbert, MD, PhD, Costin Radu, MD, PhD, Daniel Cherqui, MD, PhD, Chady Salloum, MD, Nicolas Mongardon, MD, PhD, Sami Maghrebi, MD, Karim Belhadj, MD, Fabien Le Bras, MD, Emmanuel Teiger, MD, PhD, Jean-Paul Couetil, MD, PhD, Adriana Balan, MD, Mounira Kharoubi, MSc, Mélanie Bézard, MSc, Silvia Oghina, MD, Diane Bodez, MD, PhD, Luc Hittinger, MD, PhD, Vincent Audard, MD, PhD, Violaine Planté-Bordeneuve, MD, PhD, Alexandre De la Taille, MD, PhD, Eric Bergoend, MD, Valerie Frenkel, MD, PhD, Pascale Fanen, MD, PhD, Vincent Leroy, MD, PhD, Christophe Duvoux, MD, PhD, Maryvonnick Carmagnat, PharmD, Thierry Folliguet, MD, PhD, Thibaud Damy, MD, PhD   +27 more
doaj   +1 more source

A case of cardiac amyloidosis incidentally detected by bone scintigraphy [PDF]

Asia Oceania Journal of Nuclear Medicine and Biology, 2021
A 73-year-old man with lung cancer underwent bone scintigraphy for disease staging. Diffuse myocardial technetium hydroxymethylene diphosphonate (99mTc-HMDP) uptake was incidentally found.
Hiroki Tanaka, Makoto Hosono, Mitsunori Kanagaki, Marina Shimizu, Naoko Matsubara, Kazuna Kawabata, Tadashi Miyamoto, Kazumi Itoi   +7 more
doaj   +1 more source

Tc-99m labelled bone scintigraphy in suspected cardiac amyloidosis

European Heart Journal, 2023
Aims To perform evaluation of widely embraced bone scintigraphy-based non-biopsy diagnostic criteria (NBDC) for ATTR amyloid cardiomyopathy (ATTR-CM) in clinical practice, and to refine serum free light chain (sFLC) ratio cut-offs that reliably exclude ...
M. Rauf, P. Hawkins, F. Cappelli, F. Perfetto, M. Zampieri, A. Argirò, A. Petrie, S. Law, A. Porcari, Y. Razvi, J. Bomsztyk, S. Ravichandran, A. Ioannou, R. Patel, N. Starr, D. Hutt, S. Mahmood, Brendan Wisniowski, A. Martinez-Naharro, L. Venneri, C. Whelan, Dorota Roczenio, J. Gilbertson, H. Lachmann, A. Wechalekar, C. Rapezzi, Matteo Serenelli, P. Massa, A. Caponetti, A. Ponziani, A. Accietto, A. Giovannetti, G. Saturi, M. Sguazzotti, C. Gagliardi, E. Biagini, S. Longhi, M. Fontana, J. Gillmore   +38 more
semanticscholar   +1 more source

Cardiac amyloidosis [PDF]

Clinical Medicine, 2005
Systemic amyloidosis commonly affects the heart. Indeed, cardiac symptoms may be the first clinical indicator of underlying amyloid deposition. Using two case studies, this article reviews the latest evidence regarding cardiac amyloidosis. The diagnosis of cardiac involvement can be established through imaging with echocardiography and magnetic ...
Maredia, Neil, Ray, Simon G
openaire   +2 more sources

Cardiac amyloidosis and aortic stenosis: a state-of-the-art review

European Heart Journal Open, 2023
Cardiac amyloidosis is caused by the extracellular deposition of amyloid fibrils in the heart, involving not only the myocardium but also any cardiovascular structure.
Vikash Jaiswal, Vibhor Agrawal, Yashita Khulbe, Muhammad Hanif, Helen Huang, Maha Hameed, A. Shrestha, F. Perone, Charmy Parikh, Sabas Ivan Gomez, K. Paudel, Jerome S. Zacks, Kendra J. Grubb, S. De Rosa, Alessia Gimelli   +14 more
semanticscholar   +1 more source

Evaluation of a new ELISA assay for monoclonal free‐light chain detection in patients with cardiac amyloidosis

eJHaem, 2022
The causal protein of amyloid light‐chain (AL) amyloidosis is a monoclonal immunoglobulin free light chain (mFLC), which must be quantified in the serum for patient diagnosis and monitoring.
Hajer Abroud, Asma Beldi‐Ferchiou, Vincent Audard, François Lemonnier, Fabien Le Bras, Karim Belhadj, Anissa Moktefi, Elsa Poullot, Khalil El Karoui, Jehan Dupuis, Alizée Maarek, Louise Roulin, Marie‐Hélène Delfau‐Larue, Silvia Oghina, Mounira Kharoubi, Mélanie Bézard, Amira Zaroui, Thibaud Damy, Valérie Molinier‐Frenkel   +18 more
doaj   +1 more source

Nuclear Imaging for the Diagnosis of Cardiac Amyloidosis in 2021

Diagnostics, 2021
Cardiac amyloidosis is caused by the deposition of misfolded protein fibrils into the extracellular space of the heart. The diagnosis of cardiac amyloidosis remains challenging because of the heterogeneous manifestations of the disease.
Weijia Li, Dipan Uppal, Yu Chiang Wang, Xiaobo Xu, Damianos G. Kokkinidis, Mark I. Travin, James M. Tauras   +6 more
doaj   +1 more source

Case Report and Literature Review of Cardiac Amyloidosis: A Not-So-Rare Cause of Heart Failure [PDF]

, 2023
Restrictive cardiomyopathy secondary to cardiac amyloidosis is an underdiagnosed cause of heart failure and it is associated with significant morbidity and mortality.
Alexandre, André, Baptista, Patrícia, Dias-Frias, André, Moura De Azevedo, Sofia   +3 more
core   +1 more source