Results 51 to 60 of about 37,864 (312)
Cardiac amyloidosis: clinical characteristics, prognostic factors and treatment [PDF]
, 2020 Cardiac amyloidosis occurs when misfolded protein fibrils are deposited in the extracellular space of the myocardium. The most common causes for cardiac amyloidosis are light chain (AL) amyloidosis and transthyretin (ATTR) amyloidosis.
Patel, Ketna
core
A Generalizable Deep Learning System for Cardiac MRI [PDF]
arXiv, 2023 Cardiac MRI allows for a comprehensive assessment of myocardial structure, function, and tissue characteristics. Here we describe a foundational vision system for cardiac MRI, capable of representing the breadth of human cardiovascular disease and health.
arxiv
Artificial Organs, Volume 47, Issue 1, Page 168-179, January 2023., 2023 Peak oxygen consumption, VO2peak, was associated with short‐term 3‐months‐rehospitalization in heart failure patients with reduced ejection fraction (HFrEF). Exercise oscillatory ventilation (EOV), representing fluctuations of pulmonary artery pressure, can be observed in heart failure patients with reduced ejection fraction with and without left ...
Simon Wernhart +8 more
wiley +1 more source
Frontiers in Cardiovascular Medicine, 2022 BackgroundThe t(11;14)(q13;32) is a common chromosome translocation in multiple myeloma (MM), but its prognostic value remains controversial. Immunoglobulin light chain amyloidosis is commonly secondary to multiple myeloma, which can rapidly cause heart ...
Jinghua Wang +7 more
doaj +1 more source
Cardiovascular Magnetic Resonance in Cardiac Amyloidosis [PDF]
, 2020 Background: Systemic amyloidoses are an underdiagnosed, but increasingly recognized group of progressive disorders characterised by the extracellular deposition of misfolded proteins in one or more organs.
Martinez de Azcona Naharro, Ana
core
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Cardiac amyloidosis (CA) is frequently found in older patients with aortic stenosis (AS). However, the prevalence of AS among patients with CA is unknown.
Mohamed‐Salah Annabi +16 more
doaj +1 more source
A Descriptive Analysis of ATTR Amyloidosis in Spain from the Transthyretin Amyloidosis Outcomes Survey. [PDF]
, 2021 Introduction Transthyretin amyloidosis (ATTR amyloidosis) is a clinically heterogeneous disease caused by mutations in the transthyretin (TTR) gene or aggregation of wild-type transthyretin (ATTRwt).
Amass, Leslie +9 more
core +1 more source
Nanobody interaction unveils structure, dynamics and proteotoxicity of the Finnish-type amyloidogenic gelsolin variant [PDF]
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.
Volume 1865, Issue 3, 1 March 2019, Pages 648-660, 2019 AGel amyloidosis, formerly known as familial amyloidosis of the Finnish-type, is caused by pathological aggregation of proteolytic fragments of plasma gelsolin. So far, four mutations in the gelsolin gene have been reported as responsible for the disease.
arxiv +1 more source
The prevalence and distribution of the amyloidogenic transthyretin (TTR) V122I allele in Africa [PDF]
, 2016 Transthyretin (TTR) pV142I (rs76992529-A) is one of the 113 variants in the human TTR gene associated with systemic amyloidosis. It results from a G to A transition at a CG dinucleotide in the codon for amino acid 122 of the mature protein (TTR V122I ...
Alexander, Alice A +10 more
core +1 more source
Biopsy Evidence of Sequential Transthyretin and Immunoglobulin Light-Chain Cardiac Amyloidosis in the Same Patient [PDF]
, 2021 Currently adopted diagnostic flow charts consider transthyretin and light-chain cardiac amyloidosis as mutually exclusive. Here, we report for the first time, to our knowledge, the demonstration of a biopsy-proven dual pathology in an 80-year-old man ...
Aimo A. +9 more
core +1 more source